Gayro

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The description is actual on 06.05.2015

  • Latin name: Giro
  • ATH code: P01AB03
  • Active ingredient: Ornidazol (Ornidazole)
  • Producer: Panacea Biotec (India)

Structure

With a film cover of Gayro contains in one tablet 500 mg of an ornidazol.

The list of inactive excipients includes: MKTs, lactose, aerosil-200, povidone, magnesium stearate, the purified talc, sodium lauryl sulfate, croscarmellose sodium and the purified water.

The film cover consists of a gipromelloza (GPMTs E-15), polyethyleneglycol 400, talc, quinoline yellow, diamond green, titanium dioxide, isopropyl alcohol, dichloromethane, polyethyleneglycol 6000 and the distilled water.

Release form

Gayro is a green color of an oblong biconvex shape of a tablet, having a covering — a cover, on one of the parties — to risk.

Gayro's tablets are issued in blisters on 3 pieces or 10 pieces. In one cardboard pack there can be 1, 4, 5, 7, 10 blisters on 3 pieces or 1-2 blisters on 10 pieces.

Pharmacological action

Tablets have antiprotozoan effect.

Pharmacodynamics and pharmacokinetics

Drug is antiprotozoan from what Gayro's tablets are applied in the presence of such parasites as trichomonads, lyambliya, dysenteric amoebas, such anaerobic microorganisms as bacteroids, fuzobakteriya, separate strains of clostridiums, cocci.

Pharmacokinetics

Process of absorption comes from a gastrointestinal tract, bioavailability makes 90%. Bol of 15% of Ornidazol contacts proteins of plasma. It can get through GE a barrier. T1/2 — about 13 h 5% of the accepted dose eliminirutsya in not changed look. Removal of metabolites happens 60–70% kidneys, 20–25% — to fecal masses.

Indications to use

Tablets are appointed at:

  • trichomoniasis;
  • lambliasis;
  • amebiasis (amoebic dysentery, abenteric amebiasis);
  • as a prophylactic of the infectious processes connected with anaerobic bacteria at surgical interventions and the operations performed on a colon or in gynecology.

Contraindications

  • reactions of hypersensitivity on any making tablets;
  • TsNS diseases;
  • in the first trimester of pregnancy and during feeding by a breast.

Side effects

  • headaches;
  • dizziness and other disturbances of consciousness;
  • tremor with muscle tension;
  • lacks of coordination of movements with impossibility of performance of exact movements;
  • touch neuropathy or the mixed peripheral neuropathy;
  • spasms;
  • from digestion: diarrhea, nausea, vomiting.

Application instruction of Gayro (Way and dosage)

The application instruction of Gayro differs depending on the parasite causing a disease:

  • Trichomoniasis (trichomonads): a pill is taken inside. For adults (both sexual partners) at an acute form of a disease the dose makes 1,5 g at one time or within a day, at a chronic form — accept in the morning and in the evening 500 mg of 5 days. For children calculate a one-time dose, proceeding from a formula: 25 mg on weight kg.
  • Nonspecific vaginitis: 1000 mg for 2 receptions within a day week; in pediatrics — 25 mg/kg a day 5–10 days.
  • Amoebic dysentery: 1,5 g per day, for children less than 35 kg a dose are calculated 40 mg/kg a day with body weight, to accept 3 days.
  • Other forms of an amebiasis: for adults and children of 12 flyings — to accept in the morning and in the evening 500 mg of 5-10 days. For children of 7-12 years a dose of 375 mg, 1 - 6 flying — a dose of 250 mg; 1 years — 250 mg for two receptions with an interval of 12 hours are younger. Standard course of 5-10 days.
  • Lambliasis (lyambliya): 1,5 g for 1 time, for children, weighing less than 35 kg — a dose are calculated 40 mg/kg a day and are accepted within several days.

As a prophylactic of infections anaerobic bacteria during the peredoperatsionny period — 0,5–1 grams, in postoperative — 500 mg with an interval of 12 hours for 3–5 days.

Overdose

Symptomatology: depression, epileptiform spasms, inflammation of peripheral nerves (neuritis).

For treatment carry out symptomatic therapy, when developing spasms appoint Diazepam.

Interaction

It is established that drug is capable to strengthen effects (to potentsiirovat) anticoagulants of a coumarinic row, to prolong myorelaxation Vekuroniya's influences of bromide.

Is compatible to alcohol since does not inhibit an atsetaldegiddegidrogenaza.

Terms of sale

The recipe is necessary for acquisition in a drugstore.

Storage conditions

The place protecting from penetration of moisture and rays of light, the temperature condition which is not exceeding +30 °tselsiya.

For the purpose of safety it is recommended that the place of storage was not available to children and domestic animals.

Period of validity

To store no more than three years of date on packaging.

Analogs

Coincidence on the ATH code of the 4th level:

About Gayro

About Gayro are positive. Nine of ten speak about its efficiency. Note a positive tendency of treatment together with gel Metrogil, in the presence of acute manifestations of side reactions patients replaced drug, having consulted at the attending physician.

Among positive characteristics of drug: high bioavailability, reasonable price.

Zdravzona

  • Gayro of 500 mg No. 3 tabletkipanacea Biotec
  • Gayro of 500 mg No. 10 tabletkipanacea Biotec

Drugstore of IFC

  • Gayro tbl p / about 500 mg No. 3, Panacea Biotecindiya
  • Gayro tbl p / about 500 mg No. 10, Panacea Biotecindiya
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BIOSPHERE

  • Gayro of 500 mg No. 10 of table.
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Section: Antiparasitic
in more detail

Education: Graduated from the Nikolaev national university of V. A. Sukhomlinsky, gained the diploma of the specialist with honors as "An embryologist, a cytologist, a histologist". Also, the human physiology and animals, the teacher of biology" graduated from a magistracy majoring in ". The course on discipline "Pharmacology" is with honors passable.

Experience: Worked as the senior laboratory assistant of department of Physiology and biochemistry of the Nikolaev national university of V. A. Sukhomlinsky in 2010 - 2011.

PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use of Gayro surely consult with the attending physician.