Gelmintoks

Гельминтокс Drug photo

The description is actual on 29.06.2016

  • Latin name: Helmintox
  • ATH code: P02CC01
  • Active ingredient: Pyrantelum (Pyrantel)
  • Producer: Innothera Chouzy (France)

Structure

In 1 tabletPyrantelum of 125 mg and 250 mg. Corn starch, carboxymethylstarch, magnesium stearate as auxiliary components.

In 1 spoon of suspension of Pyrantelum of an embonat of 125 mg. Sorbitol, glitserol, povidone, polysorbate, lecithin soy, Natrium benzoicum, citric acid, fragrance, silicone emulsion, magnesium aluminosilicate, water as auxiliary components.

Release form

Tablets in a cover. Ml suspension 15 in a bottle.

Pharmacological action

Anthelmintic.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

The Protivogelmintny drug causing nervously — muscular blockade and spastic paralysis of muscles of helminths. In an effect helminths are removed by the peristaltic movements of intestines from an organism together with a stake. It is effective concerning mature and unripe helminths of both floors: pinworms, ascarids, ankylostomas. Drug does not affect parasites excitingly therefore does not provoke their migration. Does not work on the migrating larvae.

Pharmacokinetics

Almost it is not absorbed from a gastrointestinal tract. The maximum concentration in blood is defined a current of 1-3 h. It is partially metabolized in a liver. About 93% are brought through intestines, and 7% — kidneys.

Indications to use

Enterobiosisankilostomidoz, ascaridosis.

Contraindications

  • hypersensitivity;
  • feeding by a breast;
  • myasthenia;
  • diseases of a liver and liver failure.

With care it is appointed at pregnancy and only if advantage for mother more risk for a fruit, to children till 6 months.

Side effects

Are in rare instances noted:

Application instruction of Gelmintoks (Way and dosage)

Pill is taken inside at any time and not necessarily on an empty stomach. Appoint to adults and children 6 years are more senior. Purgatives at the same time are not appointed. At an ascaridosis and an enterobiosis to children after 6 flyings — 1 tablet of 125 mg on 10 kg of body weight. Adults weighing less than 75 kg take 3 pill on 250 mg, with a bigger weight — 4 tablets on 250 mg.

Suspension of Gelmintoks, application instruction

Suspension before reception is well stirred up. In 1 ml of suspension of 50 mg of active agent, in 1 measured spoon — 125 mg.

At an enterobiosis and an ascaridosis appoint to children 1 measured spoon to 10 kg of weight of 1 times. Adult weighing less than 75 kg appoint 6 spoons of suspension, and weighing more than 75 kg — 8 spoons once. In 3 weeks administration of drug is repeated in the same dosages for the purpose of prevention of infection.

At dochmiases treatment is carried out 3 days. A dosage for children of 250 mg on 10 kg of weight, adult weight weighing more than 75 kg appoint 2 g a day.

During deworming carefully clean the room, wash all children's toys, daily change underwear, daily iron bed linen. Carry out treatment to all family members. In order to avoid a reinfestation it is necessary to wash carefully hands, to daily change linen, not to allow combing of a crotch. On completion of treatment conduct control research a calla.

Overdose

Overdose does not cause significant intoxication. The gastric lavage is carried out.

Interaction

Pyrantelum increases concentration in theophylline blood. At simultaneous use of sorbents reduction of efficiency of active ingredient is possible. Use with levamisole and piperazin is not recommended.

Terms of sale

It is released according to the recipe of the doctor.

Storage conditions

Temperature of storage is up to 25 °C.

Period of validity

3 years (for suspension and tablets).

Analogs

Coincidence on the ATH code of the 4th level:

Pyrantelum (tablets and suspension), Nemotsid (tablets and suspension).

About Gelmintoks

Feature of helminthoses is their prevalence mainly among the children's population. Choice drug in treatment of an ascaridosis and an enterobiosis taking into account efficiency is Pyrantelum or Gelmintoks. Clinical tests of efficiency of this drug showed its high (94–100%) activity at these invasions, at the same time it is well transferred. It confirm also numerous Gelmintoks for children.

The convenient form of release in the form of suspension of pleasant taste does not cause negative emotions in children, and they do not oppose to treatment. Besides, at these diseases of rather single dose then all parents note negative analyses on existence of eggs of worms. Some parents report that side reactions were shown by the diarrhea, insignificant abdominal pains which is not expressed by nausea.

In most cases treatment took place without side effects and this results from the fact that drug only immobilizes helminths. It is known that the death of helminths is followed by release of toxics which cause side reactions. Important the fact that before administration of drug preparation and observance of a diet is not necessary its reception does not depend on meal, is allowed for use from 6 months (some antigelmintik can be applied only since 3-6-12). The release forms for all family are had.

Zdravzona

  • Gelmintoks 250 mg No. 3 of a tabletkiinnoter of Shuzi
  • Gelmintoks 125 mg No. 6 of a tabletkiinnoter of Shuzi
  • Gelmintoks 125mg/2,5ml suspension for intake of 15 ml of a flakoninnoter of Shuzi

Drugstore of IFC

  • Gelmintoks tbl p/pl/o 125 mg No. 6, Innotechfrantion
  • Gelmintoks tbl p/pl/o 250 mg No. 3, Innotechfrantion
  • Gelmintoks susp. 5% fl 15 ml, Innotechfrantion
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Apteka24

  • Gelmintoksinnothera Chouzi (France)
  • Gelmintoksinnothera Chouzi (France)
  • Gelmintoksinnothera Chouzi (France)

Paniapteka

  • Gelmintoks tab. of 125 mg No. 6inotek

BIOSPHERE

  • Gelmintoks 125 mg No. 6 of the tab. Laboratoires Innotech International (France)
  • Gelmintoks 125 mg / 2,5 ml of 15 ml susp. for reception vnutrlaboratoires Innothera (France)
  • Gelmintoks 250 mg No. 3 of the tab. Laboratoires Innotech International (France)
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Section: Antiparasitic
in more detail

Education: Graduated from Sverdlovsk medical school (1968 - 1971) as "Paramedic". Graduated from the Donetsk medical institute (1975 - 1981) as "An epidemiologist, a hygienist". Passed postgraduate study in the Central scientific research institute of epidemiology Moscow (1986 - 1989). An academic degree – the candidate of medical sciences (degree is awarded in 1989, protection – the Central scientific research institute of epidemiology Moscow). Numerous advanced training courses are studied in epidemiology and infectious diseases.

Experience: Work as the manager of department of disinfection and sterilization of 1981 - 1992. Work as the manager of department of especially dangerous infections of 1992 - 2010. Teaching activity at Medical institute 2010 - 2013.

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