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Mikrolyut's dragee contains 0.03 mg of active component of levonorgestrel.
Roundish dragee of a white color with a glossy surface. 35 dragees are packed into extra calendar planimetric packing. In a pack from a cardboard there is 1 packaging from the dragees expected 5 weeks of use and 1 instruction.
Contraceptive. Mikrolt is the gestagenny, low-dosed medicine which is applied to contraception. Daily, regular use of levonorgestrel provides reliable contraceptive action which is reached by combined effect of several mechanisms at once. The leading role to be assigned to peripheral gestagenny effect. Active agent is capable to raise an indicator of viscosity of slime which is located in a neck of uterus (tsirvikalnaya / cervical slime) that interferes with hit of a spermatozoon in a cavity of the uterus. Active ingredient is capable to slow down endometrial proliferation that does not allow an oospore to be implanted to a uterus wall.
Mikrolt it is capable to block release of the follicle-stimulating and luteinizing hypothalamus rileasing-factors. Against reception of a medicine oppression of production of hypophyseal gonadotropic hormones is noted that in turn slows down process of an ovulation. At regular reception the volume of menstrual bleedings considerably decreases, are eliminated menstrual hurt (including premenstrual).
Pharmacodynamics and pharmacokinetics
The dragee after reception of per os is completely and quickly absorbed from a gleam of a digestive tract. At "the first passing" through hepatic system it is metabolized only partially. Active agent levonorgestrel well contacts plasma proteins. As a result of a metabolism in hepatic system conjugates (glyukuronidny and sulphatic) which are removed through an urinary path and intestines are formed.
Indications to use
Tablets of Mikrolyut are appointed in the following cases:
- replacement complex therapy by hormonal medicines;
- contraception in a complex with barrier (non-hormonal) ways of contraception;
- at bad portability, allergic reaction to estrogen-gestagennye medicines;
- emergency contraception.
- new growths in hepatic system;
- vaginal, uterine bleedings of not clear genesis;
- sugar diabetes with various vascular complications;
- thromboembolic processes;
- herpes infection;
- hemolitic anemia;
- stroke in the anamnesis;
- malignant new growths of a mammary gland, suspicion on them;
- individual hypersensitivity;
- hormonedependent cancer of an endometria / mammary gland;
- pregnancy incubation period.
- extrauterine pregnancy in the anamnesis;
- pathology of renal system;
- disturbance of passability of uterine tubes;
- diabetes mellitus without complications;
- nagrubaniye of mammary glands;
- menstrual disturbances (amenorrhea, irregular/frequent bleedings);
- allergic answers;
- depressive mood;
- skin changes (hirsutism, acne);
- deterioration in portability of contact lenses;
- change of vulval secretion;
- decrease in a libido;
- change of body weight;
Mikrolt, the application instruction (A way and a dosage)
Dragees are accepted by per os, washing down with water, not chewing. About 1 dragee in one and too is daily recommended to accept time. Therapy is begun from the first day of periods (the tablet is chosen taking into account a day of the week in calendar packaging). If in packaging dragees ended, then start administration of drug from new packaging, choosing a tablet from the cell corresponding to a day of the week. Medicine is accepted constantly, without interruption.
The clinical picture consists of the negative reactions described in the section "Side effects". Most often vulval bleedings, nausea, emetic desires are registered.
The medicines capable to reduce Mikrolyut's efficiency:
The risk of intermenstrual bleedings increases at reception by the following of drugs:
Active component Levonorgestrel is capable to reduce efficiency:
- anti-hypertensive medicines;
- peroral anticoagulants.
Terms of sale
Mikrolyut can buy in a drugstore. Presentation of the medical recipe is obligatory.
The medicine keeps the efficiency at storage at the room temperature.
Period of validity
Before reception of contraceptives gynecologic and partial therapeutic inspection is recommended, survey of mammary glands is obligatory. Survey of the doctor and all inspections it is necessary to pass each half a year. At some patients accepting a medicine break time between periods and intensity of menstrual bleeding changes; the menstrual cycle does not change. In the absence of intermenstrual bleedings more than 6 months it is necessary to address the treating doctor for a pregnancy approach exception. Treatment is continued if pregnancy is not confirmed.
Maintaining a special calendar which is applied to a medicine facilitates tracking frequency of periods. In the first 14 days of therapy contraception incomplete therefore it is necessary to resort to non-hormonal, barrier methods of contraception.
The contraceptive effect is lost if the break between receptions of tablets makes more than a day. At diarrhea, vomiting, excess body weight, obesity the contraceptive effect is lost. At sudden deterioration in acoustical or visual perception, at long migraine, pregnancy approach, increase of convulsive attacks, at suspicion on thrombosis or a thrombembolia, sharp raising of a blood pressure, emergence of jaundice the medicine is cancelled. After medicine cancellation functionality of gonads is recovered quickly enough that increases chances of approach of pregnancy.
Coincidence on the ATH code of the 4th level:
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