Seknidoks

Секнидокс Drug photo

The description is actual on 10.02.2016

  • Latin name: SECNIDOX
  • ATH code: PO1AB07
  • Active ingredient: Seknidazol (Secnidazole)
  • Producer: Bailey-Kreat's laboratory, France for World Medicine (France/Great Britain)

Structure

Seknidazol, corn starch, calcium hydrophosphate, microcrystallic cellulose, glikolit starch sodium, povidone, magnesium erases, the purified talc, a gipromelloza, titanadioksid, the purified talc, propylene glycol.

Release form

Tablets of 1.0 g, coated in planimetric packaging from aluminum foil and a polyvinyl chloride film on 2 tablets in a cardboard pack.

Pharmacological action

Anti-protozoan.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

The antiprotozoan drug with antibacterial action relating to group of nitroimidazoles possesses bactericidal and amebitsidny action. Seknidoksos it is active especially concerning trichomonads, a dysenteric amoeba, an intestinal lyambliya.

Getting into a microorganism cell, Seknidazol interacts with DNA, destroying its spiral-shaped structure, inhibition of synthesis of nucleotides and death of a cell. Drug possesses teturamopodobny action (a sensitization to alcohol), increases sensitivity of tumors to radiation.

Pharmacokinetics

Drug after intake is completely and quickly soaked up in a gastrointestinal tract, breaks a blood-brain barrier and gets into breast milk. With max in blood it is reached within 4 hours. Bioavailability about 80%. Seknidoksos it is metabolized in a liver. It is removed by kidneys for 72 hours.

Indications to use

Uretrita and the vaginita caused by a trichomonad, an intestines amebiasis, a bacterial vaginosis, a liver amebiasis, a lambliasis.

Contraindications

Organic lesions of TsNS, the increased individual sensitivity to drug, a blood disease, age till 12 flyings, the period of pregnancy and a lactation.

Side effects

Stomach aches, nausea, stomatitis, incoordination, dizziness, ataxy, urticaria, paresthesia, polyneuropathy, moderate leukopenia.

Seknidoks, application instruction (Way and dosage)

Tablets of Seknidoks is accepted before meal, washing down with water.

Doses for adults at various diseases:

Bacterial vaginosis, mecotic vaginitis and uretrita, an acute symptomatic amebiasis — once 2 tablets; asymptomatic amebiasis, including cystic and focal forms: on 2 tablets once daily within three days. At a liver amebiasis — on 1,5 tablets daily within five days. Important: at Seknidoks's reception it is impossible to take alcohol!

Doses for children are more senior than 12 years:

At an intestines amebiasisan asymptomatic amebiasis: 30 mg/kg of weight of the child within three days; acute symptomatic amebiasis and lambliasis: once, in a dose of 30 mg/kg of weight of the child. At a liver amebiasis — a separate or single dose daily for 5 days in a dose of 30 mg/kg of weight.

Overdose

Leukopenia, ataxy. Strengthening of symptomatology of collateral manifestations is also possible.

Interaction

Drug at a concomitant use strengthens action of derivatives of Coumarin (indirect anticoagulants).

The concomitant use of drug with Disulfiramum can provoke paranoiac reactions (nausea, vomiting, abdominal pains, a headache).

At simultaneous use of Seknidoks with drugs of lithium increases its concentration in blood.

Seknidoks it is not recommended to apply with muscle relaxants (bromide a vekuroniya).

Terms of sale

According to the recipe.

Storage conditions

At a temperature up to 25 °C.

Period of validity

3 years.

Seknidoks's analogs

Structural analogs of drug are: Seknizol 500, Tagera Forte.

About Seknidoks

About drug good. Most of patients note its high performance.

BIOSPHERE

  • Seknidoks 1 g No. 2 tabl.p.o. Bailey-Kreat's laboratory according to license Medrayk, for Uorld Meditsin, Great Britain (France)
to show still
Section: Antiparasitic
in more detail

Education: Graduated from Sverdlovsk medical school (1968 - 1971) as "Paramedic". Graduated from the Donetsk medical institute (1975 - 1981) as "An epidemiologist, a hygienist". Passed postgraduate study in the Central scientific research institute of epidemiology Moscow (1986 - 1989). An academic degree – the candidate of medical sciences (degree is awarded in 1989, protection – the Central scientific research institute of epidemiology Moscow). Numerous advanced training courses are studied in epidemiology and infectious diseases.

Experience: Work as the manager of department of disinfection and sterilization of 1981 - 1992. Work as the manager of department of especially dangerous infections of 1992 - 2010. Teaching activity at Medical institute 2010 - 2013.

PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before use of medicine of Seknidoks surely consult with the attending physician.