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B3 vitamin (niacin)
B3 vitamin (niacin) – vitamin, medicinal substance which participates in many cellular oxidizing reactions. Till 2008 in Russia it was used as a food additive, but today it is prohibited.
Main functions of niacin:
Participation in a metabolism of amino acids, proteins, fats. Maintenance of processes of biosynthesis. Normalization of tissue respiration. Providing a glycogenolysis – reaction which proceeds in muscles and a liver. Normalizes the level of lipoproteins of blood. Can reduce concentration of cholesterol in blood at a priyantiya of high doses (3 g/days).
- Has anti-atherogenous effect
- Expansion of blood vessels, mainly small (including brain)
- Has anticoagulating action
- Improves microcirculation
- Improves fibrinolitic blood activity
- Strengthening of effect of vasodilating drugs
- Regulates the content of glucose in blood
- Maintenance of a healthy condition of skin
B3 vitamin sources:
- Meat, kidneys, liver
- Haricot, buckwheat
15 — 20 mg are made by daily need for niacin.
For reception of B3 vitamin there is a set of indications from which it is possible to distinguish: unbalanced and defective food, malabsorption (including because of disturbance of work of a pancreas), a pellagra (the disease caused by irrational food), Hartnup's illness (disturbance of digestion of amino acids), fast weight loss, persistent diarrhea, an illness Krone, a gluten enteropathy, a gastroektomiya, cirrhosis and chronic hepatitises, long fever, persistent infections, a hyperthyroidism, pregnancy, a lactation, malignant tumors, a lipidemia, trophic ulcers and long not healing wounds, colitis, gipoatsidny gastritis, neuritis of a facial nerve, disturbance of blood circulation in a brain, diseases and vasospasms, a mikroangiopatiya, a diabetic polyneuropathy.
With caution B3 vitamin should be taken at a peptic ulcer of a 12-perstny gut and a stomach (out of an aggravation stage), hyperacid gastritis, arterial hypotension, a liver failure, a hyperuricemia, gout, glaucoma, a hemorrhage. Absolute contraindication for reception of additional doses of B3 vitamin is hypersensitivity to it, age till two years.
At overdose by niacin the hyperemia of an upper half of a trunk and face skin, dizziness, paresthesias, arrhythmia, strong skin court, nausea, vomiting, dryness mucous an eye and skin, diarrhea, a mialgiya is possible. At use a current of a long time dizziness, a headache, fatty dystrophy of a liver, feeling of heat, a hyperuricemia.
Symptoms of deficit of B3 vitamin:
- Diarrhea, disturbances in work of a gastrointestinal tract
- From TsNS: emotional instability, appetite loss, headaches, excitability, memory loss, fatigue
- Language inflammation
- Pigmentation and peelings of skin under the influence of sunshine