Akriderm of group of companies

Акридерм ГК Drug photo

The description is actual on 22.06.2016

  • Latin name: Akriderm GK
  • ATH code: D07XC01
  • Active ingredient: Betamethasone + Gentamycin + Clotrimazolum (Betamethasone + Gentamicin + Clotrimazole)
  • Producer: Quinacrine (Russia)

Structure

Active agents are a part of drug: betamethasone Dipropionas, Clotrimazolum and Gentamycini sulfas.

Additional components: vaseline, propylene glycol, a liquid paraffin, cetostearyl alcohol, macrogoal ether cetostearyl, Trilonum of B, dihydrophosphate sodium a dihydrate and the purified water.

Release form

Issue Akriderm the Civil Code in the form of cream or ointment for the drawing outwardly packaged in tubas on 15 and 30 g.

Pharmacological action

Each form of drug has antiinflammatory, antiallergic, antibacterial and antifungal effect.

Pharmacodynamics and pharmacokinetics

Effect of this combined drug is caused by its components which are a glucocorticosteroid, an antibiotic aminoglycoside and antifungal means.

Use of betamethasone of Dipropionas promotes braking of concentration of leukocytes, formation of lizosomalny enzymes and a number of antiinflammatory mediators in the field of an inflammation. At the same time there is a phagocytosis oppression, reduction of vascular and fabric permeability and the prevention of emergence of inflammatory puffiness.

The bactericidal effect is characteristic of the gentamycin which is an antibiotic with the broad spectrum of activity entering into group of aminoglycosides. Its action goes on causative agents of many primary, also consecutive bacterial infections of integuments, namely on: gram-negative and gram-positive bacteria. However anaerobe bacterias, mushrooms and viruses are not sensitive to this substance.

Antifungal effect of drug is provided thanks to Clotrimazolum. At the same time there is a disturbance of synthesis of ergosterol which makes a cellular membrane of mushrooms.

Activity is shown concerning the most widespread mushrooms: Trichophyton rubrum, Epidermophyton floccosum, Candida albicans and so on.

Indications to use

Drug Akriderm of group of companies is appointed at treatment:

Contraindications

Akriderm of group of companies is not recommended to use cream or ointment at:

Use at pregnancy

It is how safe to accept this drug at pregnancy, completely it is not established. Therefore to use ointment or cream Akriderm it is only possible for group of companies during this period when the potential advantage considerably exceeds possible risk. Anyway drugs of this group it is not necessary to use long time in the raised dosages.

Side effects

Use of GKS quite often causes such side effects as: burning, irritation, excessive xeroderma, hypertrichosis, folliculitis, acne, hypopigmentation, dermatitis and so on.

Prolonged use, especially under occlusive bandages, can cause a heat rash, maceration or an atrophy of integuments, consecutive infection, purple.

With the maximum care it is necessary to carry out treatment of children to avoid emergence of such system undesirable effects as a hyperglycemia, a glucosuria, oppression of work of bark of adrenal glands, a syndrome of Kushinga and other.

Application instruction Akriderm of group of companies (Way and dosage)

Akriderm group of companies the application instruction recommends to apply ointment only outwardly. At the same time means is applied with rather thin layer on places of defeat of integuments. It is necessary to do it every day on 2 times.

It should be noted that on cream Akriderm of group of companies the application instruction contains the same therapeutic scheme. But also appointment as the doctor of the individual treatment depending on disease severity is possible. Mild cases allow cream use only once a day, and heavier, on the contrary, increase in frequency of use.

Therapy duration usually depends on that, how effectively this means appeared in a specific case, and can make 2-4 weeks.

At long lack of a positive take specification of the diagnosis is necessary.

Overdose

Use of this drug seldom leads to development of acute overdose. However its long use in large numbers does not exclude emergence of the chronic overdose accompanied with hypercorticoidism symptoms, for example, a hyperglycemia, a glucosuria, oppression of work of bark of adrenal glands, a syndrome of Kushinga.

Emergence of undesirable effects demands carrying out symptomatic therapy with gradual drug withdrawal.

Interaction

Cases of medicinal interaction with various drugs were not revealed.

Special instructions

Emergence of symptoms of sensitivity, irritation of integuments and other undesirable signs which are caused by drug use demands refusal of this therapy and the choice of other suitable means.

Long treatment, putting cream or ointment on extensive skin surfaces, use of occlusive bandages and therapy of children can become the reason of system absorption of GKS.

This outside means can be applied at treatment of children for year, but only according to the recommendation and under careful control of the specialist that will allow to avoid manifestation of system side effects. It is established that Akriderm group of companies long time for extensive sites leads putting cream or ointment to work oppression gipotalamo - pituitary and adrenal system, to a hypercorticoidism, decrease in excretion of a growth hormone and increase in intracranial pressure.

Besides, at long drawing on the person quite often there are atrophic changes, in comparison with other sites of skin. For this reason it is necessary to adhere to a standard therapeutic course which makes 5 days.

It is contraindicated to apply any form of drug in ophthalmology, avoiding its accidental hit not only in eyes, but also mucous membranes.

Terms of sale

According to the recipe.

Storage conditions

Drug is stored at the room temperature making 15-25 °C in the place unavailable to children.

Period of validity

2 years.

The main analogs are provided by drugs: Triderm and Kanizon.

At the same time the price of analogs varies within 470-720 rubles.

About Akriderm of group of companies

According to many users, this outside means is one of the most effective. Though About cream Akriderm groups of companies meet more often than about ointment. Anyway, each of forms of this drug is appointed for treatment of various skin diseases and usually already in couple of days patients note improvement.

It should be noted that except positive responses it is possible to meet also messages on development of side effects. Symptoms which indicate intolerance or sensitivity of this drug are usually described: strengthening of reddening, peeling, development of an inflammation and so on.

Besides, quite often patients report that drug helps, only when use it, and soon after cancellation illness symptoms return again.

Most likely, the fact that Akriderm group of companies helps to suppress displays of a disease is the reason of it, but after all does not influence an illness. Therefore except the drug facilitating a condition of the patient the main treatment of a source of disturbance of health in addition has to be carried out.

Anyway it is not recommended to use this means without appointment of the specialist. Besides that therapy can be just useless, emergence of the strongest complications which usually demand prolonged treatment is not excluded.

The price Akriderm of group of companies where to buy

The cream price Akriderm of group of companies makes 130-400 rubles.

The ointment price Akriderm of group of companies – 350-650 rubles.

Zdravzona

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Drugstore of IFC

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  • Akriderm of group of companies ointment of a tube of 15 g, HFK (г.Москва) Russia Quinacrine
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Section: From an allergy Antifungal
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