Алдара Drug photo

The description is actual on 03.08.2016

  • Latin name: Aldara
  • ATH code: D06BB10
  • Active ingredient: Imikhimod (Imiquimod)
  • Producer: LABORATORIOS CASEN-FLEET, S.L.U. (Spain)


Imikhimod, acid isostearin, cetyl alcohol, paraffin white soft, stearyl alcohol, polysorbate, benzyl alcohol, sorbitan stearate, gum xanthane, propilparagidroksibenzoat, glitserol, the water purified.

Release form

Cream of 5% for external use of light yellow color in the thermowelded multilayer packages of 250 mg in cardboard packaging No. 12.

Pharmacological action


Pharmacodynamics and pharmacokinetics


The main active ingredient of drug belongs to the class of imidazokumolinamin and is the inductor of immune system. At the same time, Imikhimod does not make direct impact on a virus, and acts as the antineoplastic agent by activation of immune system through TLR7 (toll-like receptor 7).

It is also effective against viral infections. Imikhimod activates NK and B-cells, and also Langergans's cells. The main result of effect of drug is increase in production of cytokines: interleykina-6 (IL-6), alpha interferon (IFN-α) and TNF-α (factor of a necrosis of tumors). Cytokines, respectively, stimulate an immune response and increase antiviral activity.

Imikhimod also has anti-proliferative (cytostatic) effect. Stimulating development of a receptor of OGFR (an opioid growth factor), drug slows down growth of cells of malignant tumors.


At outside use through skin less than 0,9% of the put drug dose get. The insignificant quantity of an imikhimod which gets to the general blood stream to be output during a short span through urine and kcal, and its concentration in blood does not reach quantitatively defined level (> 5 ng/ml). Cmax of an imikhimod in blood comes within 10 hours and makes when drawing on face skin 1,6 ng/ml.

Indications to use

  • Treatment of the outside sharp-pointed condylomas which are localized on perianal area and on skin of external genitals;
  • In therapy of a bazalioma and actinic keratosis at patients with normal function of immune system.


Age till 18 flyings, high sensitivity to drug, pregnancy and the period of a lactation.

Side effects

Dizziness, headache, nausea, vomiting, pain and itch of skin in drug sites of application, erythematic rash, a folliculitis, diarrhea, increased fatigue, a mialgiya, grippopodobny symptoms, an arthralgia, fever, sleeplessness or drowsiness, a depression, irritability, pharyngitis, rhinitis, a back pain, perspiration, an abdominal pain, anorexia, local hyperpegmentation, a vaginitis, a herpes simplex, decrease in hemoglobin, a leukopenia.

Aldara, application instruction (Way and dosage)

Aldar's (aldara) cream is applied outwardly, it is applied on the cleared condyloma surface with a thin layer and completely rubbed in skin. It is necessary to avoid hit of cream on a skin surface outside an affected area, and also to cause its excess quantity.

After putting drug it is impossible to apply a bandage, to leave on skin about 10 hours, during this period it is impossible to accept hydrotherapeutic procedures. After the specified term cream should be washed away water with detergent. The mode of putting drug — 3 times a week once a day before going to bed. To continue treatment before disappearance of visible condylomas, however no more than 4 months. One package of Aldar is expected approximately the area of skin of 20 cm2.


Use of drug in the doses exceeding therapeutic increases risk of development of local reactions in severe forms; At accidental hit of an imikhimod inside in a dosage it is higher than 200 mg (about 16 bags), vomiting, nausea, a mialgiya, a headache, fever can be noted. In hard cases — arterial hypotension.


Extremely low absorption of drug through integuments limits interaction with HP of systemic action. To use drug with care to the patients receiving drugs immunosuppressors.

Terms of sale

According to the recipe.

Storage conditions

At a temperature up to 25 °C.

Period of validity

24 months.

Aldar's analogs

With similar medical action treat drugs: We malt, Allomedin, Aktovir, Polikrezulen, Kondilin, the Vaccine Gardasil, Imunobeks, Fenistil Pentsivir, Gerpferon, Lipster, Vratizolin and others.

About Aldare

About drug at most of patients positive: "… Excellent drug. Never would even think that Aldar's cream can be so highly effective. On a crotch two sharp-pointed condylomas developed. Advised Aldar's ointment. Used drug about a month, now everything disappeared and well skin dragged on. I already also cannot find that place where they were".


  • Aldara cream of 5% 250 mg No. 12 paketikimeda Manufacturing GmbH

Drugstore of IFC

  • Aldara cream of 5% for an external primeniye of 250 mg a pack ice. No. 12, ZM of Hels Kea Limited Gbvelikobritaniya
to show still
Section: Immunity increase
in more detail

Education: Graduated from Sverdlovsk medical school (1968 - 1971) as "Paramedic". Graduated from the Donetsk medical institute (1975 - 1981) as "An epidemiologist, a hygienist". Passed postgraduate study in the Central scientific research institute of epidemiology Moscow (1986 - 1989). An academic degree – the candidate of medical sciences (degree is awarded in 1989, protection – the Central scientific research institute of epidemiology Moscow). Numerous advanced training courses are studied in epidemiology and infectious diseases.

Experience: Work as the manager of department of disinfection and sterilization of 1981 - 1992. Work as the manager of department of especially dangerous infections of 1992 - 2010. Teaching activity at Medical institute 2010 - 2013.

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