Alpha Tocopherol acetate

• Structure
• Release form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications to use
• Contraindications
• Side effects
• Application instruction of Tocopherol of acetate (Way and dosage)
• Overdose
• Interaction
• Terms of sale
• Storage conditions
• Period of validity
• Responses

Structure

Drug contains Alpha Tocopherol acetate (vitamin E). Means in the form of solution for internal use also includes the sunflower refined oil as an additional component.

Release form

Capsules and Solutio oleosa of tocopherol of acetate of 30% for use inside.

Pharmacological action

Medicine serves for completion of a lack of vitamin E of an organism. Antioxidant.

Pharmacodynamics and pharmacokinetics

Alpha Tocopherol acetate (vitamin E) participates in a fabric exchange. This means warns hemolysiserythrocytes and emergence of peroxides which can damage cellular and subcellular membranes. Interferes with free radical reactions, emergence of degenerative and dystrophic changes in skeletal muscles and a cardiac muscle, atherosclerosis, to disturbance of work of testicles and seed tubules, and also placentae. Besides, it prevents increase in permeability and fragility of capillaries, improves reproductive function. Normalizes food and sokratitelny ability of a myocardium, tissue respiration. Reduces consumption by an oxygen myocardium. Gem and gemsoderzhashchy enzymes, and also in protein synthesis helps with synthesis. Protects vitamin A from oxidation. Interferes with oxidation of selenium and unsaturated fatty acids. Blocks cholesterol synthesis.

Tocopherol acetate for the person at regular use allows to achieve the following results:

• aging delay – skin remains tightened and elastic, without wrinkles longer;
• healing of the damaged sites – wounds heal much quicker;
• prevention of oncological diseases;
• improvement of protection of integuments against ultraviolet rays – reddenings, burns and other reactions which can be provoked by sunshine appear less often;
• normalization of a condition of skin – tocopherol interferes with a peeling, reduces fat content of skin and helps to control work of sebaceous glands, it also oxygenates a cell, promotes regeneration. Skin has healthier and attractive appearance without surgical interventions.

Drug after use inside is slowly absorbed approximately for 50%. The maximum concentration in blood is observed 4 hours later. For absorption bile acids are necessary. At absorption the complex with lipoproteids – intracellular carriers of tocopherol is created.

Active component comes at first to a lymph, and after that to the general blood stream in which communicates mainly with alfa1-and beta lipoproteids and, part, – with a seralbumin. Accumulates in adrenal glands, seed plants, muscular tissue, a liver, a hypophysis, lipidic fabric, erythrocytes. It is split and brought out of an organism mainly with bile. A quantity of drug is allocated with urine.

Indications to use

This medicine is applied at a hypovitaminosis, heavy exercise stresses, diseases of the copular device and muscles, conditions of reconvalescence after diseases with a feverish syndrome, at advanced age. Besides, it helps with a case of climacteric vegetative disturbances, an asthenic neurotic syndrome, a posttraumatic myopathy, a neurasthenia at overfatigue, primary muscular dystrophy, a postinfectious secondary myopathy, degenerative and proliferative changes in joints and the copular device of a backbone.

Contraindications

Medicine cannot be applied at hypersensitivity to its components, a myocardial infarction, a cardiosclerosis.

With care it should be used in case of a prothrombinopenia.

Side effects

At use of this means allergic reactions, diarrhea, pains in epigastriums are possible. In case of intramuscular introduction – infiltrate in an injection site, morbidity.

Application instruction of Tocopherol of acetate (Way and dosage)

The usual dosage makes 100-300 mg daily. If it is necessary, it can be raised to 1 g a day.

The application instruction of Tocopherol of acetate reports that exact doses and duration of a course are selected depending on the reception purpose:

• for prevention accept every day 100 mg 1-2 times, the course lasts 1-3 weeks;
• disturbance of a spermatogenesis – is accepted by 100-300 mg every day as making hormonal therapies, the course is expected a month;
• disturbance of a menstrual cycle – in a day it is necessary to accept 300-400 mg. It is necessary to begin from 17 in the afternoon a cycle and throughout five cycles;
• climacteric vegetative frustration – 100 mg the 3rd time/day;
• anemia – 200 mg a day;
• hypertensia because of pregnancy – 100 mg in the I trimester every day or in a day;
• the liver illness with the aggravation periods – is accepted by 300 mg a day for several months;
• diseases of neuromuscular system – accept daily 100 mg, treatment lasts 1-2 months, the course can be repeated 2-3 months later;
• at teenage age prior to hormonal therapy – it is necessary to accept problems with a menstrual cycle 1-2 times a day on 100 mg, treatment lasts 2-3 months;
• threat of abortion – accept daily or in a day 100 mg in the I trimester;
• neurasthenia because of overfatigue – accept daily 100 mg, treatment lasts 1-2 months;
• diseases of integuments – 100 mg a day for 20-40 days.

Overdose

At overdose by medicine the creatinuria, decrease in working capacity, pain in epigastriums are possible. Means is cancelled, appoint glucocorticoids and carry out a symptomatic treatment. There is no specific antidote.

Interaction

The combination to Warfarin and Dikumarol can lead to change of their action. Decrease in efficiency of medicines with iron is possible. Use with Cyclosporine increases its absorption.

Terms of sale

Without recipe.

Storage conditions

It is necessary to keep drug in the dark place, optimum temperature – 18–20 °C. To protect from children.

Period of validity

Two years.

Alpha Tocopherol acetate – Responses

About Tocopherol what is it and as to accept it, often try to learn on the Internet. This means is recommended not only by specialists, but also those who already tried it on themselves. You will not meet negative opinions on it. All call efficient Alpha Tocopherol medicine acetate – It receives exclusively positive. Especially often they are left by women who accepted drug for normalization of a menstrual cycle or during pregnancy. They note that it is much more available than analogs with vitamin E.

Alpha Tocopherol acetate – the price

The price of Tocopherol depends on a release form. The cost of capsules approximately from 20 rubles. And the price of solution of 30% – about 70 rubles. Among analogs this means is considered very available. Therefore quite often prefer to buy Alpha Tocopherol acetate – the price and the scheme of use of this drug are pleasant to much.