Allergodil

Аллергодил Drug photo

The description is actual on 06.01.2015

  • Latin name: Allergodil
  • ATH code: R01AC03
  • Active ingredient: Azelastin (Azelastine)
  • Producer: Meda Pharma, Germany

Structure

Drops eye — in 1 ml 0,5mg an azelastina of a hydrochloride and excipients.

Spray for a nose dosed — in 1 fl. 0,01g azelastina of a hydrochloride and excipients.

Release form

Drops are eye, 0,05% in a bottle with a dropper on 6 and 10 ml.

Spray nasal with the sprayer doser in bottles on 10 ml.

Pharmacological action

Antihistaminic, antiallergic.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

Is the selection blocker of H1-of receptors. Has antihistaminic and membranostabiliziruyushchy effect, reduces permeability of capillaries and interferes with release from mast cells of the active agents (serotonin, a histamine, leukotrienes) causing allergic reactions and a bronchospasm.

At introduction to a nose reduces a congestion, sneezing and allocations from a nose. After use in 15 min. subsiding of symptoms is noted, action continues 12 hours and more. At an instillation in an eye the antiinflammatory effect is in addition shown. Systemic action is expressed slightly at topical administration.

Pharmacokinetics

At introduction to a nose bioavailability makes 40%. Within 2-3 hours the maximum concentration in blood which is 8 times lower, than at esperimentalny administration of drug inside is reached. At patients with allergic rhinitis, concentration of drug higher, than at healthy.

At use of eye drops (1 drop / 4 times) the maximum concentration in plasma very low.

Indications to use

Spray for a nose Allergodil

  • allergic seasonal and nonseasonal rhinitis;
  • vasculomotor (not allergic) rhinitis.

Eye drops Allergodil

  • seasonal allergic conjunctivitis;
  • inflammatory diseases of eyes of various genesis, including posttraumatic;
  • year-round allergic conjunctivitis.

Contraindications

  • hypersensitivity to drug and its components;
  • pregnancy and lactation;
  • age till 6 flyings (for nasal spray);
  • renal failure (for nasal spray);
  • age till 4 flyings (for eye drops).

Side effects

Eye drops

  • the raised slezootdeleniye;
  • reddening, swelled;
  • morbidity, irritation;
  • itch;
  • hematopsia;
  • feeling of a foreign body;
  • vision disorder;
  • xerophthalmus;
  • blepharitis.

The general manifestations are noted seldom: difficulty of breath, difficulty of defecation.

Nasal spray

  • burning in a nose, sneezing, an itch;
  • nasal bleeding;
  • nausea (at introduction with the thrown-back head and hit in a nasopharynx);
  • rash, skin itch;
  • dryness in a mouth, a gastralgia;
  • weakness, dizziness;
  • constraint in a thorax.

The instruction on Allergodil (A way and a dosage)

Nasal spray Allergodil, application instruction

Spray nasal has the sprayer doser that considerably facilitates use. Before the first use it is necessary to spray several times means in air. Inject a necessary dose into each nasal course, the head at the same time needs to be held directly.

Allergic rhinitis also rinokonjyunktivit: to adults and children since 6 — on 1 dose (one pressing the sprayer) in both nostrils in the morning and in the evening. Perhaps increase in a dose to children is more senior than 12 years to 2 doses in both nostrils 2 times a day. Allergodil it is necessary to apply to a nose before the termination of symptoms. It can be applied it is long, but no more than 5 - 6 months are continuous.

Vasculomotor rhinitis: to adults and children, since 12 flyings — 2 doses in each nasal course in the morning and in the evening. Also it is applied before the termination of symptoms, duration of continuous treatment at this disease should not make more than 2 months.

Eye drops Allergodil, application instruction

Are dug in in a conjunctival sac.

Seasonal allergic conjunctivitis: to adults and children since 4 — 1 drop in both eyes in the morning and in the evening. Use to 4 times a day is in case of need possible. At this disease drug is used also for the purpose of prevention.

Nonseasonal allergic conjunctivitis: to adults and children since 12 — 1 drop in both eyes in the morning and in the evening. Use to 4 times a day on 1 drop is possible.

Overdose

Cases are not registered.

Interaction

Allergodil strengthens sedative effect of ethanol and means, the oppressing TsNS. Cimetidinum increases concentration of active ingredient in plasma, and Ketokonazol reduces.

Terms of sale

It is released without recipe.

Storage conditions

Temperature of storage is 8–25 °C. It is impossible to freeze.

Period of validity

3 years.

Special instructions

At an instillation in an eye it is impossible to carry contact lenses. Other eye drops appointed in complex therapy should be dug in with an interval of 15 minutes. To consider a possibility of dizziness and drowsiness at Allergodil's use.

Allergodil's analogs

Coincidence on the ATH code of the 4th level:

Azelastina a hydrochloride (eye drops), Allergodil With (spray nasal). Analogs have approximately the same cost.

Zdravzona

  • Allergodil spray the nasal Manufacturing GmbH dosed 140mkg/dose 10mlmeda
  • Allergodil of a drop eye 6mlmeda Manufacturing GmbH
  • Allergodil of 140 mg nasal spray 10mlmeda Manufacturing GmbH
  • Allergodil About spray the nasal Manufacturing GmbH dosed 137mkg/dose 30mlmeda
  • Allergodil About spray naz. 137mkg/dose (200 doses) 30 ml + drops eye 0,05% 6mlmeda Manufacturing GmbH

Drugstore of IFC

  • Allergodil of a drop eye 0.05% 6 ml, ASTA Medicagermaniya
  • Allergodil of a drop eye 0.05% 6 ml, Tubilix Pharma S.p.A/Santen Oyitaliya
  • Allergodil About spray nazaln. 0.14mg/dose 30 ml, Manufakchuring Gmbkhgermaniya's HONEY
  • Allergodil spray nazaln. 0.14mg/dose 10 ml, Manufakchuring Gmbkhgermaniya's HONEY
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Apteka24

  • Allergodiltubilux (Italy)
  • Allergodilmeda Manufacturing (Germany)

Paniapteka

  • Allergodil of hot-smoked 0.05% 6mlursafarm
  • Allergodil of hot-smoked 0.05% 6mlursafarm
  • Allergodil of hot-smoked 0.05% 6mlursafarm
  • Allergodil of hot-smoked 0.05% 6mlursafarm
Section: For eyes From an allergy From cold
in more detail

Education: Graduated from Sverdlovsk medical school (1968 - 1971) as "Paramedic". Graduated from the Donetsk medical institute (1975 - 1981) as "An epidemiologist, a hygienist". Passed postgraduate study in the Central scientific research institute of epidemiology Moscow (1986 - 1989). An academic degree – the candidate of medical sciences (degree is awarded in 1989, protection – the Central scientific research institute of epidemiology Moscow). Numerous advanced training courses are studied in epidemiology and infectious diseases.

Experience: Work as the manager of department of disinfection and sterilization of 1981 - 1992. Work as the manager of department of especially dangerous infections of 1992 - 2010. Teaching activity at Medical institute 2010 - 2013.

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