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In 1 capsule of Ampicillini trihdras and Oxacillinum of sodium salt on 0,125 g. Potato starch, sugar, talc, gipromelloz, magnesium stearate as excipients.
In 1 bottle of ampicillin of sodium of 133,4 mg or 333,5 mg, Oxacillinum of sodium of 66,6 mg or 166,5 mg.
Capsules of 20 pieces in packaging.
Powder in bottles.
Pharmacodynamics and pharmacokinetics
The antibiotic relating to semi-synthetic penicillin contains a combination of ampicillin and Oxacillinum and integrates a range of their action on microorganisms. Kislotoustoychiv, works bakteritsidno.
Shows activity in relation to gram-positive (a pneumococcus, a streptococcus, staphylococcus) and gram-negative (colibacillus, meningokokk, shigellas, gonokokk, a stick of an influenza, a salmonella) microorganisms. Presence of Oxacillinum does drug active concerning penitsillinazoustoychivy stafilokokk. Pseudomonas aeruginosa, many strains of Proteus vulgaris, Morganella are steady against Ampioks's action.
The maximum concentration in blood of both antibiotics is noted in 30-50 min. after intramuscular introduction. Both antibiotics are allocated with kidneys and partially — with bile. Cumulation at repeated introductions is not noted.
Indications to use
- sinusitis, average otitis;
- bronchitis, pneumonia;
- cystitis, urethritis;
- ugly face, impetigo;
- endocarditis, meningitis;
- prevention of postoperative complications;
- puerperal infection.
- infectious mononucleosis;
- toksiko-allergic reactions to penicillin drugs;
- lymphoid leukosis.
With care it is applied at children whose mothers have hypersensitivity to penicillin.
- nausea, vomiting;
- taste change;
- liquid chair;
- pseudomembranous coloenteritis.
At parenteral administration:
- acute anaphylaxis;
- morbidity in the place of an injection.
Application instruction of Ampioks (Way and dosage)
Drug has two dosage forms.
Tablets of Ampioks, application instruction
Capsules of Ampioks Health are accepted inside. For adults and children of 14 years a single dose of 0,5-1,0 g (2-4 capsules) which is accepted 4 times a day, thus a daily dose — 2-4 g. To children at the age of 7-9 flyings appoint 1,25 g a day, 10-14 years – 1,75 g a day. Duration of treatment depends on a disease and makes from 7 days to 2 weeks.
Ampioks's pricks, application instruction
Before purpose of injections of this drug it is necessary to define sensitivity of microflora to it. Ampioks-natry, intended for injections, enter intramusculary or intravenously, having dissolved powder in water for injections.
Single dose for adults — 0,5-1,0 g, enter it 4 times a day in 6 — 8 h. If necessary the dose increases by 1,5-2 times. Newborn appoint 100-200 mg to weight kg a day. Course of treatment from 7 to 21 days.
For intravenous administration drug is dissolved in 15 ml of normal saline solution and slowly entered. For intravenous drop use dissolve in 200 ml of physical solution. At drop introduction to children apply 5% glucose solution in number of 30-100 ml. Solutions use at once. Intravenously enter 5-7 days, if necessary pass to intramuscular introduction.
At use of high doses for patients with a renal failure there is a probability of toxic action on TsNS. Symptomatic therapy is carried out.
Slow down absorption and the following drugs reduce its degree: glycosamine, antacids, purgatives, aminoglycosides, and also meal. Ascorbic acid strengthens absorption of active agents. Antibiotics rifampicin, aminoglycosides, Vancomycinum, cephalosporins have sinergidny effect. And macroleads, streptocides, chloramphenicol, tetracyclines, linkozamida — antagonistic.
Ampioks strengthens effects of anticoagulants, reduces action of oral contraceptives. Diuretics, Allopyrinolum, NPVN, phenylbutazone, probenetsid, increase concentration of active agents in plasma that attracts risk of toxic action. At reception of Allopyrinolum the risk of emergence of rash increases.
Terms of sale
According to the recipe.
Temperature is up to 25 °C.
Period of validity
Use of drug at pregnancy
Widespread mistake is refusal of doctors of purpose of antibacterial therapy. At pregnancy, at pneumonia because of fear of negative influence of medicines on a fruit. Actually the list of the antibacterial drugs contraindicated during this period, is very limited - it is tetracyclines, streptocides, chloramphenicol, co-trimoxazole, aminoglycosides and ftorkhinolona. β-laktamny antibiotics to which Ampioks belongs and also macroleads are applied at pregnant women. These are not the toxic antibiotics which were not exerting impacts on a fruit.
Coincidence on the ATH code of the 4th level:
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