Analdim

Анальдим Drug photo

The description is actual on 15.07.2016

  • Latin name: Analdim
  • ATH code: N02BB52
  • Active ingredient: Metamizole sodium + Difengidramina hydrochloride (Metamizole sodium + Diphenhydramine hydrochloride)
  • Producer: JSC Monfarm (Ukraine)

Structure

In 1 suppository 100/10 — analginum (metamizole sodium) of 100 mg and a Dimedrol of 10 mg.

In 1 suppository 250/20 — analginum of 250 mg and a Dimedrol of 20 mg.

Release form

Candles rectal No. 10.

Pharmacological action

Anesthetizing and febrifugal.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

The combined drug, as a part of which two active ingredients — analginum and a Dimedrol. Analginum — the non-narcotic analgesic possessing the expressed analgetic antipyretic action. Inhibits activity of enzyme of cyclooxygenase that attracts delay of a metabolism of arachidonic acid and decrease in level of prostaglandins at the expense of what carrying out a painful impulse is oppressed. Influencing the center of thermal control has febrifugal effect. The Dimedrol possesses antihistaminic action and sedative as gets through a blood-brain barrier. Increases efficiency of analginum at the combined use.

Pharmacokinetics

Active components are well absorbed in blood. The peak of their concentration is reached in 1-2 hours. Both are metabolized in a liver. Are removed mainly with urine in the form of metabolites and in an invariable look. An analginum elimination half-life 2-4 hour, a Dimedrol — 1-4 hours. Effect of drug remains 5 hours.

Indications to use

  • febrifugal at inflammatory diseases;
  • tooth and headache;
  • neuralgia;
  • muscular pains;
  • hepatic and renal gripes;
  • stopping of a pain syndrome after injuries and operations.

Contraindications

  • hypersensitivity;
  • deficit glyukozo-6-fosfatdegidrogenazy;
  • blood diseases;
  • heavy abnormal liver functions or kidneys;
  • bronchial asthma;
  • pregnancy and lactation;
  • age till 1 year.

With care it is appointed to persons, managing directors of the car and dangerous mechanisms.

Side effects

  • weakness, drowsiness;
  • dizziness, headache;
  • dryness mucous mouth;
  • frustration of a chair;
  • nausea;
  • changes from blood (at prolonged use).

Analdim, application instruction (Way and dosage)

It is intended for introduction to a rectum. Duration of a course is determined by the doctor. It is not recommended to apply more than 4 days. At a pain syndrome — single use. To adults and teenagers appoint candles Analdy 250 on 1 suppository 1-2 times a day.

To children from 5 to 14 years appoint drug in the same dosage only 1 time a day.

Analdim for children from 1 year to 4 flyings has the smaller content of active ingredients. At this age apply candles Analdim 100. Frequency rate of use of 1 times a day. Therapeutic action after rectal use is observed 1-2 hours later.

Overdose

Cases are not registered.

Interaction

Strengthens effects of acetylsalicylic acid, streptocides, alcohol, antimicrobic drugs and anticoagulants of a coumarinic row. Reduces concentration of cyclosporine. Development of a hyperthermia at use with fenotiaziny and Chlorpromazinum is possible.

Phenylbutazone and barbiturates reduce efficiency of drug. Toxicity of drug increases at use with non-steroidal anti-inflammatory drugs, Allopyrinolum and tricyclic antidepressants. It is impossible to appoint jointly with means which have a promoting effect on the central nervous system (Cavintonum, caffeine, piracetam).

Terms of sale

Without recipe.

Storage conditions

Temperature is from 8 to 15 °C.

Period of validity

2 years.

Analogs

Efferalgan, Tsefekon, Nurofen.

About Analdim

Most often, as an antipyretic, apply to Analdy children therefore also responses are connected using it in this age category. About drug versatile that is connected with individual sensitivity. Many parents give preference to drugs of the paracetamol having less than side effects, but not analginum.

  • "… Analdim always helps us quite effective and available febrifugal drug will cope with high temperature,".
  • "… Means really effective! The nurofen in syrup is weaker and if to combine both drugs, then good effect".
  • "… Does not help my children at all".
  • "… 5-6 hours therefore I put a candle for the night work. Sleeps peacefully".
  • "… I prefer to apply for the night as from them slackness and drowsiness from a Dimedrol appears at the child".
  • "… From the Nurofen at the daughter vomiting, and these candles transfers well. Are effective".
  • "… In comparison with other candles they thaw much quicker and introduction becomes problematic".
  • "… My child is helped by candles on the basis of paracetamol. I do not want to give to the child analginum".

Anyway, candles are applied situationally — 3-4 times for all days of temperature increase therefore it is not necessary to speak about undesirable effects.

Apteka24

  • Suppositories analdy 100mg/10mg No. 10monfarm (Ukraine, Monastyrishche)
  • Suppositories analdy 250mg/20mg No. 10monfarm (Ukraine, Monastyrishche)

Paniapteka

  • Soup. analdy 100mg/10mg No. 10monfarm
  • Soup. analdy 100mg/10mg No. 10monfarm
Section: Anesthetics
in more detail

Education: Graduated from Sverdlovsk medical school (1968 - 1971) as "Paramedic". Graduated from the Donetsk medical institute (1975 - 1981) as "An epidemiologist, a hygienist". Passed postgraduate study in the Central scientific research institute of epidemiology Moscow (1986 - 1989). An academic degree – the candidate of medical sciences (degree is awarded in 1989, protection – the Central scientific research institute of epidemiology Moscow). Numerous advanced training courses are studied in epidemiology and infectious diseases.

Experience: Work as the manager of department of disinfection and sterilization of 1981 - 1992. Work as the manager of department of especially dangerous infections of 1992 - 2010. Teaching activity at Medical institute 2010 - 2013.

PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use Analdim surely consult with the attending physician.