Арутимол Drug photo

The description is actual on 19.07.2016

  • Latin name: Arutimol
  • ATH code: S01ED01
  • Active ingredient: Timololum (Timololum)
  • Producer: Laboratoire Chauvin (France)


Timololum hydromaleate, chloride solution benzalkoniya, povidone, dihydrosodium phosphate dihydrate, monohydrophosphate sodium dodecahydrate, dihydrate edetat dinatrium, water sterile.

Release form

Eye drops of 0,25% and 0,5% a type of inodorous colourless transparent solution in a polyethylene bottle of 5 ml in cardboard packaging.

Pharmacological action


Pharmacodynamics and pharmacokinetics


Drug protivoglaukomny, belongs to group non-selective a blocker of adrenoceptors β1 and β2. Has no sympathomimetic and membranstabiliziruyushchy effect. Local effect of drug is shown by decrease in intraocular pressure, at the same time, normal VGD decreases as raised, and. This process happens due to decrease in a producing intraocular liquid. Drug of influence does not render on accommodation and the size of a pupil. Action after an instillation in a conjunctival sac is shown in 30 minutes, reaches the maximum value in one hour remains for days.


Drug at local purpose of system absorption is exposed in insignificant degree. Timololum Cmax in the water environment of an anterior chamber of an eye after instillation comes in 2 hours. Actively active ingredient of drug gets to a system blood stream in insignificant quantity, being absorbed through vessels of the lacrimal path, conjunctiva and mucous a nose. It is removed with urine in the form of metabolites.

Indications to use

  • Eye hypertensia, secondary glaucoma, open angle glaucoma;
  • In the combined treatment of closed-angle glaucoma, as additional HP for decrease in VGD together with miotika);
  • Treatment of inborn glaucoma in cases of insufficient efficiency of other HP.


HOB, bronchial asthma, heart failure, age till 18 flyings, the period of pregnancy and a lactation, allergic reactions to drug, cardiogenic shock, atrophic rhinitis, dystrophic processes in a cornea, a sinus bradycardia. To apply with care at a diabetes mellitus, cerebrovascular insufficiency, a thyrotoxicosis, a hypoglycemia, Reynaud's syndrome, a myasthenia.

Side effects

Are shown as the general reactions (fast fatigue, nausea, diarrhea, a disorientation and weakness, bradycardia, breath disturbances, a bronchospasm, hypotonia, a blepharitis, a keratitis, conjunctivitis, rhinitis, allergic reactions, hallucinations, and local (a hyperemia and irritation of a conjunctiva, an itch and burning in eyes, a photophobia, dacryagogue, a superficial keratopathy, cornea hypostasis, a diplopia, the small tortoiseshell).

Arutimol, application instruction (Way and dosage)

To dig in eye drops Arutimol of 0,25% or 0,5% on 1 drop in a conjunctival sac 2 times a day. After decrease in VGD pass to the supporting dosage — on 1 drop of 0,25% of solution once a day. Prolonged treatment with insignificant breaks.


Emergence of system effects which are characteristic at reception of HP of beta adrenoblockers is in rare instances noted: headache, dizziness, bradycardia, nausea, vomiting, decrease in the ABP, arrhythmia, bronchospasm, heart failure.


The concomitant use of drug with eye drops as a part of which contains containing Epinephrinum and Pilocarpinum increases risk of a mydriasis. At joint reception of Arutimol with Reserpinum, blockers of calcium channels and beta adrenoblockers decrease in the ABP and delay of a cordial rhythm can be exponentiated. The concomitant use with insulin or hypoglycemic means can cause a hypoglycemia. Timololum exponentiates therapeutic action of muscle relaxants, its cancellation two days prior to surgical intervention under the general anesthesia is necessary.

Terms of sale

Issue according to the recipe.

Storage conditions

At a temperature up to 25 °C. Eye drops in opened a bottle are suitable for use for 6 weeks.

Period of validity

3 years.


Coincidence on the ATH code of the 4th level:

Structural analogs on active agent are: Okumol, Oftan, Timogeksal, Okuker, Timadren, Glautam, Timololum Long, Okumed, Niolol, Okupres-E, Timololum. With similar medical action treat drugs: Ganfort, Ksalaky, Ksonef, Betoptik, Duotrav, Azarga, Kombigan, Duoprost, Anaprilin, Betaksolol, Betoftan, Optibetol.

About Arutimole

About drug among patients favorable. "… I am treated Arutimol nearly 2 years with breaks. With its help it is possible to support intraocular pressure so far though the doctor offers laser correction". In practice often use Arutimol at a hemangioma, especially at a hemangioma at children of infantile age at their primary manifestations and having the small sizes.


  • Arutimol of 0,5% of a drop eye 5 ml bottle dropper
  • Arutimol of 0,25% of a drop eye 5 ml bottle dropper

Drugstore of IFC

  • Arutimol of a hl drop. 0.5% fl-cap of 5 ml, Amcapharm Pharmaceutical Gmbhgermaniya
  • Arutimol of a hl drop. 0.25% fl-cap of 5 ml, Amcapharm Pharmaceutical Gmbhgermaniya
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  • Arutimolchauvin ankerpharm (Germany)
  • Arutimolchauvin ankerpharm (Germany)


  • Arutimol of hot-smoked 0.25% 5mlankerfarm CHAUVIN
  • Arutimol of hot-smoked 0.25% 5mlankerfarm CHAUVIN


  • Arutimol of 0,25% 5 ml of a drop glazn.ankerpharm (Germany)
  • Arutimol of 0,5% 5 ml of a drop glazn.ankerpharm (Germany)
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Section: For eyes
in more detail

Education: Graduated from Sverdlovsk medical school (1968 - 1971) as "Paramedic". Graduated from the Donetsk medical institute (1975 - 1981) as "An epidemiologist, a hygienist". Passed postgraduate study in the Central scientific research institute of epidemiology Moscow (1986 - 1989). An academic degree – the candidate of medical sciences (degree is awarded in 1989, protection – the Central scientific research institute of epidemiology Moscow). Numerous advanced training courses are studied in epidemiology and infectious diseases.

Experience: Work as the manager of department of disinfection and sterilization of 1981 - 1992. Work as the manager of department of especially dangerous infections of 1992 - 2010. Teaching activity at Medical institute 2010 - 2013.

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