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The description is actual on 30.04.2013
Nonsteroid antiinflammatory medicine. Medicine in not selective order brakes activity of enzymes cyclooxygenase 1 and 2 (regulate synthesis of prostaglandins). Medicine Aspikor has analgeziruyushchy (anesthesia), antiinflammatory and febrifugal effects. Active agent acetylsalicylic acid slows down formation of prostaglandins under the influence of which the hyperalgesia and puffiness forms. Decrease in level of prostaglandins in the main center of thermal control (mainly to E1) causes strengthened sweating, expansion of a gleam of blood vessels of skin and, as a result, decrease in body temperature. Analgetic influence is reached peripheral and central by actions of a medicine. Aspikor suppresses synthesizing of A2 thromboxane in blood cells thrombocytes, reduces a thrombogenesis, adhesion of thrombocytes and their aggregation. At patients with the unstable course of stenocardia active agent acetylsalicylic acid allows to lower a lethality, risk of development of a myocardial infarction. The Antiagregantny effect lasts about a week after reception of a single dose. The daily dosage of 6 grams also more raises a prothrombin time, suppresses synthesis of a prothrombin in hepatic fabric. Medicine Aspikor increases the frequency of hemorrhagic complications at operative measures. Under the influence of a medicine removal of uric acid amplifies (as a result of disturbance of a canalicular reabsorption in kidneys). Aspikor is issued in the tableted medicinal look (kishechnorastvorimy, sparkling, children's, in a cover).
Medicine Aspikor is appointed for stopping of a pain syndrome (the weak and moderately expressed forms) of various origin: migraine, headaches, mialgiya, radicular syndrome, algodismenoreya, arthralgia, lumbago, neuralgia, dentagra. The medicine is applied at a feverish syndrome against infectious, inflammatory pathology.
The tablet Aspikor is not appointed at hemorrhagic diathesis, at an individual form of intolerance of acetylsalicylic acid, at bronchial asthma, bleedings from a digestive tract, at erosive cankers of the alimentary system, simultaneous therapy of methotrexates, pregnancy incubation (the first, third trimesters), feeding a breast and to children before achievement of fifteen-year age.
Tablets Aspikor can make diarrhea, sick, allergic answers in the form of a Quincke's disease, skin rash and a bronchospasm. Against treatment disturbances in work of kidneys and hepatic system, development of a syndrome to Reja (fast forming of a liver failure, dystrophy of a liver and encephalopathy), a leukopenia, the thrombocytopenia expressed to anemia are possible. Long therapy can be followed by hypocoagulation, erosive cankers of a digestive tract, dizzinesses, migraine, vomiting, disturbances of visual perception, intersticial nephrite, bleedings, a papillary necrosis, a prerenalny azotemia with a hypercalcemia and a giperkreatininemiya, puffiness, strengthening of symptomatology of heart failure, aseptic meningitis, increase of enzymes of a liver, a nephrotic syndrome.
Route of administration:
Pill Aspikor is taken inside. At a pain, feverish syndrome the medicine is accepted inside to 3 grams (the recommended dose of 0,5-1 grams a day) on 3 receptions. As analgeziruyushchy and anti-inflammatory drug Aspikor appoint 325 mg in a dose. Duration of therapy should not exceed more than two weeks. Sparkling forms a medicine need preliminary to be dissolved in 100-200 ml of water. One-time amount of drug of 0,25-1 grams (3-4 times a day).
Drug use Aspikor as an antiinflammatory medicine is limited because of high risk of development of the NPVS-gastropathy. Duration of therapy should not exceed more than 5 days. Responses on drug Aspikor testify to good tolerance and high performance of drug at observance of all of the recommendation. Now medicine is not appointed at a rheumatic chorea, an infectious and allergic form of myocarditis, at a pseudorheumatism, and also at a pericardis and rheumatism. Aspikor is recommended to cancel in 5-7 days prior to planned operation. Prolonged treatment the calla on the occult blood demands obligatory control over indicators of blood, the analysis. The medicine is capable to make teratogenic impact. Acetylsalicylic acid is emitted with breast milk. The medicine can provoke a bad attack of gout. The price of drug Aspikor makes 50 rubles. Aspikor's analogs: tromboass, atsekardol, kardiomagnit.
The application instruction of drug Aspikor does not recommend to apply a medicine along with peroral hypoglycemic means, valproic acid, a methotrexate, antiagregant, trombolitika, indirect anticoagulants, heparin, streptocides, hypotensive and uricosuric means, diuretics. The risk of gastrointestinal bleedings increases at simultaneous therapy by glucocorticosteroids and etanolsoderzhashchy medicines. Aspikor is capable to increase concentration of barbiturates, digoxin, lithium salts in plasma. Absorption of acetylsalicylic acid decreases at treatment by antacids. Gematotoksichesky influence of Aspikor increases at treatment by myelotoxic medicines.
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