Atsekardol

Ацекардол Drug photo

The description is actual on 07.12.2015

  • Latin name: Acecardol
  • ATH code: B01AC06
  • Active ingredient: Acetylsalicylic acid
  • Producer: Synthesis (Russia)

Structure

1 tablet contains 50 or 100 mg of active agent acetylsalicylic acid.

Act as additional components: povidone, sterat magnesium, starch, monohydrate of lactose, microcrystallic cellulose, talc.

The cover consists from: tsellatsefata, titanium dioxide and castor oil.

Release form

Is issued in the form of tablets with a kishechnorastvorimy cover.

Pharmacological action

Antiagregant. NPVS.

Pharmacodynamics and pharmacokinetics

Active ingredient — acetylsalicylic acid. The possibility of inhibition of cyclooxygenase active component is the cornerstone of the mechanism of action that causes braking of production of A2 thromboxane, decrease in aggregation of platelet cells. The antiagregantny effect reached by reception of one tablet remains within a week.

High dosages of a medicine are capable to have anesthetic and antipyretic effect (over 300 mg). Medicine is completely soaked up in a digestive tract and only partially metabolized in the course of absorption.

Indications to Atsekardol's use

From what tablet?

Atsekardol appoint at unstable stenocardia, for the prevention of a repeated myocardial infarction, for the prevention of a thromboembolism of a pulmonary artery (including its branches) and a deep vein thrombosis (at long stay in a motionless state, for example, during long surgical intervention).

Medicine is appointed to patients with risk factors (the increased body weight, the increased cholesterol level, a diabetes mellitus, smoking, age, an arterial hypertension) for the prevention of an acute myocardial infarction.

The application instruction of Atsekardol recommends a medicine to patients after invasive interventions and operations on vessels (stenting, angioplasty of carotid arteries, endarterectomy of carotid arteries, aortocoronary shunting, arteriovenous shunting) for the prevention of a thromboembolism.

Medicine is appointed to patients with passing disturbance of blood supply of a brain for the prevention of a stroke on ischemic type.

Contraindications

Medicine do not appoint to patients with erosive and ulcer diseases of a digestive tract, with hemorrhagic diathesis, gastromenias, a duodenum. Medicine is not appointed at the bronchial asthma caused by reception of salicylates.

Drug is contraindicated at liver diseases, at heart failure, at pathology of renal system, when feeding by a breast.

Unacceptably simultaneous treatment with a methotrexate in a dosage more than 15 mg a week.

Atsekardol's use is limited at patients with a hyperuricemia, gout, a medicamentous allergy, hay fever, polipozy a nose.

Acetylsalicylic acid can become the bleeding reason during surgical intervention.

Side effects

Digestive tract: increase of level of ALT and nuclear Heating Plant enzymes, vomiting, heartburn, nausea, cankers and bleedings.

System of a hemopoiesis: anemia, risk of bleedings because of inhibition of aggregation of platelet cells.

Allergic answers in the form of cardiorespiratory a distress syndrome, puffinesses of mucous walls of a nasal cavity, rhinitis, the small tortoiseshell, a Quincke's edema, an itch and rash. Seldom heavy allergic reaction as an anaphylaxis develops.

Respiratory system: spasm of bronchial tubes of small and average caliber.

Nervous system: disturbance of acoustical perception, sonitus, headaches, dizzinesses.

Atsekardol, application instruction (Way and dosage)

Medicine is recommended to be taken before food. It is desirable to wash down tablets with the sufficient volume of liquid. Medicine is appointed it is long. Frequency rate of reception – pass 1 time.

At suspicion for prevention appoint to an acute myocardial infarction daily 100 mg or on 300 mg every other day. Chewing of a tablet provides faster effect that is very important during the first hours at a myocardial infarction. With at once several risk factors for prevention for the first time of the arisen acute myocardial infarction appoint 300 mg every other day, or on 100 mg daily.

The prevention of unstable stenocardia, repeated heart attack, prevention of passing disturbance of brain blood supply, stroke on ischemic type: 100-300 mg every day.

For prevention of a thromboembolism of a pulmonary artery, a deep vein thrombosis appoint 300 mg every other day, or on 100 mg daily.

Overdose

Such not heavy symptoms as are possible: dizziness, nausea, headache, confusion of consciousness, sonitus, strong sweating, tachypnea, hyperventilation. In this case treatment will assume a gastric lavage, the big use of absorbent carbon, recovery of water and electrolytic balance.

At strong weight of overdose are possible: very high temperature of a body, disorder of breath, cardiovascular system, a nervous system, metabolism of glucose, bleeding in a stomach and an intestinal path. And this case urgent hospitalization is necessary.

Interaction

Atsekardol is capable to strengthen effect of heparin, a methotrexate, anticoagulants of indirect influence (because of functional disturbance in thrombocytes), antiagregant and thrombolytic medicines, digoxin (in view of lowering of its excretion by renal system), hypoglycemic means, valproyemy acid (the mechanism is based on its replacement from communication with plasmatic proteins).

The risk of bleedings increases at use of antiagregant, trombolitik and anticoagulating means.

Strengthening of toxic influence of ethanol for work of a brain and a nervous system at simultaneous alcohol intake is noted.

Atsekardol is capable to weaken action of a benzbromarin and other uricosuric medicines (the mechanism is based on competitive decrease in renal excretion of uric acid in tubules), diuretics (in view of reduction in the rate of filtering at the level of balls), APF inhibitors.

System glucocorticosteroids weaken Atsekardol's action due to strengthening of elimination of salicylates.

Terms of sale

Atsekardol can buy in a drugstore without presentation of the recipe.

Storage conditions

In the place, unavailable to children, at a temperature no more than 25 degrees Celsius.

Period of validity

No more than three years.

Special instructions

Atsekardol can provoke a spasm of bronchial tubes and attacks of bronchial asthma. Risk factors: existence in the anamnesis polypose of a nose, hay fever, medicamentous allergy, bronchial asthma.

The reached effect of inhibition of aggregation of thrombocytes remains within several days that can serve as the reason of bleedings at the emergency operative measures. Before planned operations the medicine is cancelled at least in 7 days.

Atsekardol in small dosages can cause gout in predisposed patients. In a zone of risk of the person with reduced excretion of uric acid.

At increase of a dose of drug the risk of bleedings of a digestive tract considerably increases.

Atsekardol does not make impact on ability to steer the car. At treatment by glucocorticosteroids it is necessary to consider that at their cancellation overdose by salicylates is possible.

At pregnancy

Drug use to pregnant women, especially in 1 and 3 trimesters is inadmissible.

Analogs it is possible to call drugs: Tromboass, Kardiomagnil, Aspinat, Acenterine, Aspirin.

About Atsekardole

According to responses, Atsekardol — an effective remedy according to indications to use. Facilitates a state at heart attack. Possesses low toxicity, not strongly harms a stomach.

Atsekardol's price where to buy

Medicine is sold in packagings on 30 tablets.

The cost of tablets on 50 mg makes about 25 rubles, Atsekardol's price of 100 mg — 30 rubles, 300 mg — 50-55 rubles.

Zdravzona

  • Atsekardol of 100 mg No. 30 tabletkisintez joint stock company
  • Atsekardol of 300 mg No. 30 tabletkisintez joint stock company
  • Atsekardol of 50 mg No. 30 tabletkisintez joint stock company
  • Atsekardol of 100 mg No. 50 tabletkisintez joint stock company
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BIOSPHERE

  • Atsekardol of 100 mg No. 30 tabl.p.o.rastvor./kishechn. Synthesis of joint stock company (Russia)
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Section: For blood Cardiological Cardiovascular
in more detail

Education: Graduated from the Bashkir state medical university majoring in "Medical business". In 2011 gained the diploma and the certificate in Therapy. In 2012 received 2 certificate and the diploma in "Functional diagnosis" and "Cardiology". In 2013 completed courses on "Topical issues of otorhinolaryngology in therapy". In 2014 completed advanced training courses in "A clinical echocardiography" and courses in "Medical rehabilitation".

Experience: From 2011 to 2014 the Policlinic No. 33 Ufa worked as the therapist and the cardiologist in MBUZ. Since 2014 the Policlinic No. 33 Ufa works as the cardiologist and the doctor of functional diagnosis in MBUZ.

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