ATSTS 100

АЦЦ 100 Drug photo

The description is actual on 05.03.2016

  • Latin name: ACC 100
  • ATH code: R05CB01
  • Active ingredient: Acetylcysteinum (Acetylcysteine)
  • Producer: Salutas Pharma, Hermes Arzneimittel (Germany)

Structure

Active ingredient Acetylcysteinum (100 mg) and other auxiliary ingredients is a part of medicine ATsTs 100: anhydrous citric acid, Natrii hydrocarbonas, anhydrous lactose, anhydrous sodium carbonate, sodium saccharinate, Mannitolum, sodium citrate, ascorbic acid, fragrance.

Release form

ATsTs 100 is made in the form of tablets sparkling. They are ploskotsilindrichesky, round, white color. Possess aroma of blackberry. There can be a slight smell of sulfur. After cultivation solution without color, transparent turns out. It has a blackberry smell, can possess weak aroma of sulfur.

Pharmacological action

Substance Acetylcysteinum is derivative cysteine amino acids. Mucolytic influence of this substance on an organism is noted. Under its influence process of an otkhozhdeniye of a phlegm as Acetylcysteinum directly affects a phlegm, in particular, on its rheological properties is facilitated. As a result, viscosity of a phlegm decreases. Drug also provides antioxidant action, protecting cells from the free radical oxidation happening at strong inflammatory reactions. It is active if at the patient the purulent phlegm separates.

Under the influence of Acetylcysteinum process of synthesis of the glutathione which is to important components of a chemical detoxication, and also anti-oxidizing system improves.

If Acetylcysteinum is applied for the purpose of prevention, then at the people suffering from a mucoviscidosis and bronchitis chronic expressiveness and frequency of aggravations of a bacterial origin decreases.

Pharmacokinetics and pharmacodynamics

High level of absorption is noted. The metabolism occurs in a liver, at the same time the active metabolite – cysteine, and also other metabolites is formed. Bioavailability level — 10%, communication with blood proteins — 50%. The greatest concentration is noted in an organism in 1-3 hours. It is removed through kidneys, semi-removal time – about 1 hour.

Indications to use

Use of ATsTs 100 is shown in such cases:

  • diseases of a respiratory organs at which the viscous phlegm which difficult separates is formed, (bronchitis acute, chronic and obstructive, asthma bronchial, laryngotracheitis, tracheitis, lung abscess, pneumonia, a bronchoectatic disease, a bronchiolitis);
  • mucoviscidosis;
  • sinusitis acute and chronic;
  • HOBL;
  • average otitis.

Contraindications

Appoint ATsTs 100 in such cases:

  • hypersensitivity to Acetylcysteinum or to any other ingredients of medicine;
  • pneumorrhagia;
  • bleeding is pulmonary;
  • aggravation of a peptic ulcer;
  • pregnancy and chest feeding;
  • glyukozo-galaktozny malabsorption;
  • lack of lactase, intolerance lactose organism;
  • age of the child till 2 flyings.

It is necessary to apply ATsTs 100 carefully at an ulcer of a duodenum and stomach in the anamnesis, in case of intolerance of a histamine, at bronchial asthma, varicosity of veins of a gullet, an illness of adrenal glands, obstructive bronchitis, insufficiency of hepatic and renal, arterial hypertension.

Side effects

Manifestation of a number of side effects at use of this means is probable:

Sparkling tablets ATsTs 100, application instruction (Way and dosage)

The application instruction of ATsTs 100 provides that drug of 100 mg needs to be used orally after meal.

To patients after 14 flyings — according to the 2nd tab. 2-3 of time a day.

Reception of 1 tab. 3 times a day or according to 2 tab. 2 times a day is shown to children and teenagers from 6 to 14 years.

The instruction on ATsTs 100 for children from 2 to 6 years provides reception according to 1 tab. 2-3 of time a day.

To patients with a mucoviscidosis whose weight more than 30 kg, if necessary the dose is raised to 800 mg of Acetylcysteinum a day.

Tablets of 100 mg dissolve in 1 glass of liquid, it is necessary to accept solution at once.

Overdose

At overdose by drug nausea, pain in a stomach, heartburn, diarrhea is possible. Dangerous side effects at overdose were not observed.

Interaction

If to accept ATsTs 100 with other antitussives, development of stagnation of slime because of suppression of a tussive reflex is possible. It is necessary to practice such combination of drugs with care.

Acetylcysteinum strengthens vasodilating effect of nitroglycerine on condition of a concomitant use of these drugs.

Acetylcysteinum is not combined with antibiotics (cephalosporins, penicillin, Amphotericinum In, Tetracycline, Erythromycin) and proteolytic enzymes pharmaceutical.

At simultaneous use Acetylcysteinum reduces absorption of cephalosporins, Tetracycline, penicillin. It is necessary to adhere to an interval not less than two hours between receptions of these drugs.

In case of contact of Acetylcysteinum with metals, rubber, etc. sulfides are formed.

Terms of sale

ATsTs 100 can be bought without recipe.

Storage conditions

It is necessary to store at a temperature no more than 30 degrees, to protect from children, from hit of moisture and light.

Period of validity

3 years store ATsTs 100.

Special instructions

It is important to use ware from glass at drug cultivation to avoid contact with rubber, substances which easily ignite metals.

Seldom or never at reception of Acetylcysteinum heavy allergic reactions were noted. If changes of integuments and mucous are noted, it is necessary to see a doctor, having at once stopped reception.

It is carefully necessary to accept AZZ to 100 people who have obstructive bronchitis and bronchial asthma, at the same time it is important to control bronchial passability constantly.

It is not recommended to accept ATsTs 100 before going to bed, it is desirable to do it till 18:00.

Does not influence ability of the person to work with dangerous mechanisms, to drive transport.

Analogs

Drugs analogs ATsTs 100 — AZZ Longum, Fluimucil, Acetylcysteinum, Atsetal, Atsestad, Atsestin, etc. Only the specialist has to choose optimum drug.

Zdravzona

  • Azz 100mg/5ml granules for preparation of syrup 60 of flakonhexal Pharma Gmbh
  • Azz of 100 mg No. 20 of a tablet sparkling for deteyhexal Pharma Gmbh
  • Azz of 100 mg of a granule for Preeg. solution for intake of 3 g No. 20 paketikihexal Pharma Gmbh
  • Azz of 100 mg of a granule for Preeg. solution for intake of 3 g No. 1 paketikhexal Pharma Gmbh

Drugstore of IFC

  • ATsTs 100 tbl thorn. 100 mg No. 20, Hexal Aggermaniya
to show still

Paniapteka

  • AZZ 100 time. for the ave. solution 100 of mg No. 20sandoz
  • AZZ 100 time. for the ave. solution 100 of mg No. 20sandoz
  • AZZ 100 time. for the ave. solution 100 of mg No. 20sandoz
  • AZZ 100 time. for the ave. solution 100 of mg No. 20sandoz
  • AZZ 100 time. for the ave. solution 100 of mg No. 20sandoz
Section: For cough
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Education: "Pharmacy" graduated from the Rovno state basic medical college majoring in. Graduated from the Vinnytsia state medical university of M. I. Pirogov and internship on its base.

Experience: From 2003 to 2013 – worked at positions of the pharmacist and manager of a pharmaceutical booth. It is awarded by diplomas and distinctions for long-term and honest work. Articles on medical subject were published in local editions (newspaper) and on various Internet portals.

PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before use of ATsTs 100 medicine surely consult with the attending physician.