Азилект Drug photo

The description is actual on 22.07.2016

  • Latin name: Azilect
  • ATH code: N04BD02
  • Active ingredient: Razagilin (Rasagiline)
  • Producer: Teva Pharmaceutical Industries, Ltd. (Israel)


Razagilina mezilat, starch corn, silicon dioxide colloid, Mannitolum, stearic acid, starch corn prezhelatizirovanny, talc.

Release form

Tablets of 1 mg of a round form ploskotsilindrichesky white color in the blister in cardboard packaging No. 30, 100.

Pharmacological action


Pharmacodynamics and pharmacokinetics


Drug belongs to group of the MAO HP-selection inhibitors of V type, possesses protivoparkinsonichesky action. As a result of an inhibiting effect on MAO the level of a dopamine increases in TsNS and process of formation of toxic free radicals who are much formed at Parkinson's illness is slowed down. Drug also possesses neurotyre-tread action. In therapeutic doses of Azilekt does not block a metabolism of the biogenic amines arriving with food, respectively, hypertensive tyramine - the caused syndrome is absent.


After intake drug is quickly soaked up in a gastrointestinal tract. Cmax in blood is reached in 20-30 minutes. Bioavailability of drug at the level of 40%. Linkng with blood proteins varies from 60% to 80%. Razagilin biotransformirutsya almost completely in a liver by dealkylation and a hydroxylation with formation of a low-active metabolite of aminoindan. It is removed by kidneys and partially through intestines.

Indications to use

As drug for monotherapy or in a combination with other HP for treatment of an illness of Parkinson.


High sensitivity to drug, the accompanying therapy by MAO inhibitors, age till 18 flyings, a liver failure, pregnancy and a lactation.

Side effects

The general weakness, dizziness, headaches, depression, spasms, anorexia, loss of appetite, dyspepsia, arthritis, arthralgia, pain in a neck, dermatitis, vezikulobullezny rash, stenocardia, a leukopenia, allergic reactions, conjunctivitis, rhinitis, fever.

Azilekt, application instruction (Way and dosage)

To accept on one tablet in (1 mg) once a day in the form of monotherapy or together with a levodopa, it is long.


Overdose by drug is shown by postural hypotension, arterial hypertension.


It is impossible to accept along with other MAO inhibitors because of high risk of development of hypertensia. Joint administration of drug with the sympathomimetic HP containing ephedrine and dextromethorphan is not recommended.

At a concomitant use of drug with inhibitors of the return serotonin reuptake, tetracyclic and tricyclic antidepressants there is a high risk of development of a serotoninovy syndrome which is shown by motive concern, confusion of consciousness, a fever, diarrhea, a tremor.

Terms of sale

Prescription issue.

Storage conditions

At a temperature up to 25 °C.

Period of validity

3 years.

Azilekt's analogs

Razagilin, Razagilina mezilat.

About Azilekta

According to responses of doctors, drug intake of Azilekt at early stages of a disease authentically slows down rates of its progressing.


  • Azilekt 1 mg No. 30 tabletkiteva Pharmaceutical
  • Azilekt 1 mg No. 100 tabletkiteva Pharmaceutical
  • Azilekt 1 mg No. 10 tabletkiteva Pharmaceutical

Drugstore of IFC

  • Azilekt tbl 1 mg No. 30, Tevaizrail
to show still
Section: Others
in more detail

Education: Graduated from Sverdlovsk medical school (1968 - 1971) as "Paramedic". Graduated from the Donetsk medical institute (1975 - 1981) as "An epidemiologist, a hygienist". Passed postgraduate study in the Central scientific research institute of epidemiology Moscow (1986 - 1989). An academic degree – the candidate of medical sciences (degree is awarded in 1989, protection – the Central scientific research institute of epidemiology Moscow). Numerous advanced training courses are studied in epidemiology and infectious diseases.

Experience: Work as the manager of department of disinfection and sterilization of 1981 - 1992. Work as the manager of department of especially dangerous infections of 1992 - 2010. Teaching activity at Medical institute 2010 - 2013.

PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before use of medicine of Azilekt surely consult with the attending physician.