Азицин Drug photo

The description is actual on 13.07.2016

  • Latin name: Azicin
  • ATH code: J01FA10
  • Active ingredient: Azithromycin (Azithromycin)
  • Producer: Pharmaceutical firm of Darnits (Ukraine)


In 1 tablet of 500 mg of azithromycin.

Release form

Tablets in a cover, capsules.

Pharmacological action


Pharmacodynamics and pharmacokinetics


Active agent azithromycin — semi-synthetic substance from group of antibiotics macroleads. Has high acid resistance in comparison with other macroleads. It is characterized by bacteriostatic action, and concerning some strains — bactericidal. Azithromycin inhibits protein synthesis in the cell of microorganisms that leads to oppression of their reproduction.

Bacteriostatic action is shown concerning gram-positive and gram-negative aerobic microorganisms, in t of ohms number producing beta lactamelements. To active ingredient microorganisms of Enterobacteriaceae, Pseudomonas spp and Acinetobacter spp have resistance. It is also inefficient in the relation to the microorganisms steady against erythromycin.


At intake it is well absorbed in a gastrointestinal tract. Reception with food reduces bioavailability and absorption. Does not change under the influence of acid medium in a stomach. The maximum concentration in plasma is noted in 2-3 hours. Extent of communication with proteins to 50%. The maximum concentration of active agent are defined in almonds, exudate of a middle ear, mucous respiratory tracts and urinogenital system. Drug has ability to collect in lysosomes, and then to be released at phagocytosis. The metabolism passes in a liver. Also 6% with urine are allocated with bile. The elimination half-life — 35-50 hours, at some patients is 80 hours.

Indications to use

  • Diseases of urinogenital system;
  • infections, sexually transmitted;
  • diseases of a respiratory organs and ENT organs (bronchitis, pneumonia, sinusitis, quinsy, pharyngitis, otitis, laryngitis);
  • diseases of soft tissues (the impetigo, the ugly face, a folliculitis infected dermatitis and wounds);
  • Lyme's illness;
  • Helicobacter pylori eradikation.


  • Hypersensitivity to macroleads;
  • age till 3 flyings (a tablet and a capsule);
  • the expressed abnormal liver functions;
  • body weight at children to 25 kg;
  • pregnancy and lactation.

With care it is appointed at a heavy renal failure.

Side effects

Azitsin, application instruction (Way and dosage)

Is accepted inside on an empty stomach (in 2 hours after or in 1 hour prior to meal). Swallow of a tablet or a capsule entirely, washing down with liquid. Doses of drug are defined by the doctor depending on a condition of the patient.

At diseases of ENT organs and respiratory tracts appoint Azitsin 500 mg of 1 times a day 3 days. At skin infections — 500 mg in the first day, then 250 mg once a day. Average terms of treatment — 5 days.

At STD of 1000 mg once.

At a peptic ulcer in combination with Helicobacter pylori — on 1000 mg of times a day 3 days.

At Lyme's illness — 1000 mg in the first day, then on 500 mg a day 5 days. In general on a course of 3000 mg of drug.


It is shown by nausea, vomiting, stomach aches, diarrhea. Emergence of a headache, a hearing disorder and development of cholestatic hepatitis is possible. The specific antidote does not exist. The gastric lavage, reception of a sorbent is carried out, symptomatic therapy is carried out. At a serious poisoning extracorporal hemosorption is carried out.


At joint appointment with antacids azithromycin absorption in this connection reception of these drugs is carried on time is slowed down (an interval not less than 2 hours). Does not influence action and pharmacokinetics of medicines which are metabolized by system of P450 cytochrome (digoxin, midazolam, ergot alkaloids, theophylline, Bromocriptinum).

Terms of sale

According to the recipe.

Storage conditions

At a temperature up to 25 °C.

Period of validity

2 years.

Azitsin's analogs

Azitrox, Azitsin, Azithromycin, Azivok, Azaks, Sumamed, Azitsid, Zitrotsin, Sumamoks, Hemomitsin, Ecomedical.

About Azitsin

Drug selectively collects in the infected fabric and at the same time it is noted it therapeutic concentration. Such unique fabric orientation allows to apply it only once in days and the short modes of dosing. FDA in the USA registered even a single dose at treatment of average otitis at children. According to experts, such mode of dosing has high performance.

Azitsin's use is highly effective at the urogenital infections resistant to treatment by penicillin and cephalosporins. An optimum ratio efficiency — the cost, the dosing mode, and also a variety of dosage forms explain wide use of drug in practice of doctors of different specialties. All these moments are noted in responses of patients:

  • "… Effective, for the second day of reception felt considerable simplification at purulent quinsy. Chose it because it costs 3 times cheaper than Sumamed".
  • "… Strong antibiotic. In three days got rid of antritis".
  • "… Efficiency of an antibiotic — pleases three days, and you are healthy".
  • "… Yes, effective, but I from it had a diarrhea".
  • "… Saw I and the son at different times and in different occasions, the effect was, pobochek did not notice".

It should be noted and high safety of drug — side effects meet infrequently and there is no its significant interaction with medicines. Also the fact that at the short-term mode of reception drug does not influence flora of intestines and an oral cavity is important.


  • Azitsin of a capsule 0.25g No. 6darnitsa (Ukraine, Kiev)
  • Azitsin of a tablet coated 0.5g No. 3darnitsa (Ukraine, Kiev)


  • Azitsin kaps. 0.25g No. 6darnitsa
  • Azitsin kaps. 0.25g No. 6darnitsa
Section: Antibiotics
in more detail

Education: Graduated from Sverdlovsk medical school (1968 - 1971) as "Paramedic". Graduated from the Donetsk medical institute (1975 - 1981) as "An epidemiologist, a hygienist". Passed postgraduate study in the Central scientific research institute of epidemiology Moscow (1986 - 1989). An academic degree – the candidate of medical sciences (degree is awarded in 1989, protection – the Central scientific research institute of epidemiology Moscow). Numerous advanced training courses are studied in epidemiology and infectious diseases.

Experience: Work as the manager of department of disinfection and sterilization of 1981 - 1992. Work as the manager of department of especially dangerous infections of 1992 - 2010. Teaching activity at Medical institute 2010 - 2013.

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