Bagomet

Багомет Drug photo

The description is actual on 18.07.2016

  • Latin name: Bagomet
  • ATH code: A10BA02
  • Active ingredient: Metforminum (Metformin)
  • Producer: QUIMICA MONTPELLIER, S.A. (Argentina)

Structure

Metforminum hydrochloride of a gipromelloz, magnesium stearate, povidone, monohydrate of lactose, opadray, titanium dioxide, sodium saccharinate, macrogoal, vanillin.

Release form

Tablets kapsulovidny (round), the prolonged action of 500, 850 and 1000 mg of white color in a film cover, biconvex in the blister on 10 tablets in cardboard packaging No. 30.

Pharmacological action

Hypoglycemic.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

Drug slows down process of a gluconeogenesis in a liver, lowers absorption of glucose from intestines and improves its utilization, lowers the level of lipoproteins and triglycerides in blood, improves sensitivity of various fabrics to insulin. At the same time, drug, does not affect insulin secretion process with a pancreas. Drug loses or stabilizes body weight.

Pharmacokinetics

Medicine is quickly absorbed from a gastrointestinal tract. Bioavailability — 50-60%. Practically does not contact blood proteins. Therapeutic concentration in blood is reached on average in 2 hours. It Kumulirutsya in a liver, kidneys and sialadens. It is allocated with urine in an invariable look.

Indications to use

In complex therapy of a diabetes mellitus of type 2 at inefficiency of a dietotherapy.

Contraindications

High sensitivity to drug, a renal failure, fever, dehydration, a hypoxia, extensive surgeries, diabetic ketoacidosis, the period of pregnancy and a lactation, lactoacidosis, an alcoholism, age till 10 flyings, an acute alcoholic poisoning.

To take with caution to patients 60 years are more senior.

Side effects

Lack of appetite, nausea, smack of "metal" in a mouth, vomiting, abdominal pains, a meteorism, lactic acidosis, diarrhea, a hypoglycemia, anemia megaloblastny, local allergic reactions.

Bagomet, the instruction on (A way and a dosage)

Bagomet's dose is defined by the doctor depending on the content of glucose in blood. To take a pill entirely, washing down with water. The maximum dosage — 3000 mg/days. As a rule, an initial dose of drug — 500-1000 mg a day. Depending on expressiveness of a glycemia in 2 weeks it is possible to increase a dosage gradually. The supporting dosage — 1500-2000 mg/days. For the purpose of minimization of risk of development of by-effects the daily dose is recommended to be taken for 2 - 3 receptions.

Overdose

At Bagomet's reception in the doses exceeding recommended lactoacidosis which symptoms are decrease in temperature, nausea, pains in epigastriums, vomiting, diarrhea, mialgiya, further — dizziness, increase of breath, a lump is possible.

Interaction

At joint reception of Bagomet with sulfonilmochevina derivatives, insulin, NPVS, Oxytetracyclinum, inhibitors of a monoaminooxidase, an angiotensin-converting enzyme, ß adrenoblockers, cyclophosphamide and derivatives of Clofibratum the risk of strengthening of hypoglycemic effect of drug increases.

At joint reception with glucocorticosteroids, Epinephrinum, sympathomimetics, oral contraceptives, a glucagon, diuretics, drugs of niacin and a fenotiazin decrease in hypoglycemic effect of Bagomet is possible. Drug weakens effect of anticoagulants. Cimetidinum reduces speed Bagomet's removal that increases risk of emergence of lactoacidosis. Alcohol intake against treatment by Bagomet can lead to development of lactoacidosis.

Terms of sale

Issue according to the recipe.

Storage conditions

At a temperature up to 25 °C.

Period of validity

2 years.

Bagomet's analogs

Glikomet-500, Vero-Metformin, Gliformin, Glikon, Glyukofazh, Gliminfor, Dianormet, Metadiyen, Diforminum, Metospanin, Lanzherin, Metfogamma, Metforminum, Novoformin, Siofor, Sofamet, Formetin and others.

About Bagometa

About drug among doctors positive. "… Bagomet provides stability of concentration of Metforminum in a blood plasma for 12 hours that allows to reduce frequency rate of administration of drug and to improve control of metabolic processes. It also allows to improve process of absorption of Metforminum of a stomach and to minimize risks of side effects from a gastrointestinal tract".

In practice of treatment at inefficiency of a dietotherapy as drug of the second line the combined Bagomet's drug plus which part two peroral hypoglycemic means are is widely used: Glibenclamidum and Metforminum.

Zdravzona

  • Bagomet of 1000 mg No. 60 tabletkiquimica Montpellier S.A.
  • Bagomet Plus of 500 mg +2,5mg No. 30 tabletkiquimica Montpellier S.A.
  • Bagomet Plus of 500 mg +5mg No. 30 tabletkiquimica Montpellier S.A.
  • Bagomet of 500 mg No. 30 tabletkiquimica Montpellier S.A.
  • Bagomet of 850 mg No. 60 tabletkiquimica Montpellier S.A.
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Section: For a liver
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Education: Graduated from Sverdlovsk medical school (1968 - 1971) as "Paramedic". Graduated from the Donetsk medical institute (1975 - 1981) as "An epidemiologist, a hygienist". Passed postgraduate study in the Central scientific research institute of epidemiology Moscow (1986 - 1989). An academic degree – the candidate of medical sciences (degree is awarded in 1989, protection – the Central scientific research institute of epidemiology Moscow). Numerous advanced training courses are studied in epidemiology and infectious diseases.

Experience: Work as the manager of department of disinfection and sterilization of 1981 - 1992. Work as the manager of department of especially dangerous infections of 1992 - 2010. Teaching activity at Medical institute 2010 - 2013.

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