Баклосан Drug photo

The description is actual on 24.06.2014

  • Latin name: Baclosan
  • ATH code: M03BX01
  • Active ingredient: Baclofenum (Baclofen)
  • Producer: Pharmaceutical Works POLPHARMA, S.A. (Poland)


One tablet of drug contains 25 mg or 10 mg of Baclofenum as active agent.

Excipients: lactose, gelatin, potato starch, magnesium stearate, talc, ethyl cellulose.

Release form

Baklosan represents biconvex, round, with a dividing strip white tablets. 50 such tablets in a polypropylene can, one such can in a paper pack.

Pharmacological action

Myorelaxation and anti-spastic effects are characteristic of drug.

Pharmacodynamics and pharmacokinetics


Baklosan treats muscle relaxants of the central action; GABAB receptors inhibitor. Lowers excitability of distal departments of the sensitive fibers bringing nervous impulses and oppresses intermediate cells of a nervous system. Oppression of a synoptic momentum transfer results; undervoltage of muscle fibers. Drug does not influence transfer of nervous impulses in muscular and nervous synapses.

At the diseases which are characterized by pathological constant contractility of skeletal muscles medicine Baklosan facilitates spasms and cricks. Drug increases amplitude of movements in joints, simplifies carrying out a kinesitherapy (massage, gymnastics, manual therapy).


After reception of a tablet of Baklosan are adsorbed in intestines of high degree. The maximum concentration in blood is observed in three hours after drug use.

Linkng with proteins of plasma reaches 30%. Drug gets through a placental barrier, is removed with breast milk. The metabolism occurs in a liver. It is allocated with urine in an original form.

Indications to use

Drug is used in connection with increase in a tone of muscles at:

  • pathologies of a spinal cord (tumor, injuries, myelosyringosis, diseases of motor neurons);
  • multiple sclerosis;
  • cerebral palsy;
  • cerebrovascular diseases;
  • meningitis;
  • head injuries.


Contraindications to Baklosan's use are:

Baklosan with care use at insufficiency of blood supply of a brain, atherosclerosis of cerebral vessels, a renal failure, at elderly people and children is younger than three years.

Side effects

  • From the musculoskeletal device: mialgiya.
  • From a nervous system: weakness, dizziness, gait disturbance, sleeplessness, sedation, depression, euphoria, adynamy, tremor, hallucinations, nightmares, nystagmus, paresthesias, dysarthtia.
  • From respiratory system: respiratory depression.
  • From cardiovascular system: reduction of cordial emission, hypotension.
  • From organs of sight: visual disturbances.
  • From system of digestion: diarrhea, lock, dyspepsia, nausea, abdominal pains, damage of a liver.
  • From urinogenital system: enuresis, a polyuria, an ischuria, sometimes — erectile dysfunction.
  • From skin: hyperhidrosis.
  • General disturbances: fall of temperature.

In extremely exceptional cases increase in spasms came to light that was estimated as a paradoxical effect from administration of drug.

Application instruction of Baklosan (Way and dosage)

The application instruction of Baklosan recommends to accept drug orally together with food. If one administration of drug was by mistake missed, next time it is not necessary to use a double dose.


Starting dose — 5 mg (a half of a tablet of 10 mg) three times a day, with increase in a dose by 5 mg every three days and so before medical effect (as a rule, 30-75 mg a day there are enough). The maximum day dose – 100 mg.

The final dose should not lower a tone of muscles, lead to the expressed myasthenia or worsen motor functions.

At a renal failure or during a hemodialysis a day dose – 5 mg.

At persons 65 years a dose are more senior it is necessary to raise with care as at them the risk of development of by-effects is high.


Starting dose — 5 mg three times a day. If it is necessary a dose it is possible to increase every three days by 5 mg the medical effect will not appear yet.

The recommended doses: for children age of 3-6 years – 20-30 mg/days; 6-10 years – 30-60 mg/days; 10 years a limit day dose – 2.5 mg/kg of weight, a starting dose – 1.5-2 mg/kg of weight are more senior.

Drug withdrawal is made slowly (within 10-14 days).

Overdose by Baklosan

Overdose symptoms: respiratory depression, hypomyotonia, coma, confusion of consciousness.

Treatment: the plentiful use of liquid, use of diuretics, at oppression of respiratory function – artificial ventilation of the lungs. The antidote is unknown.


At combined use Baklosan activates effect of the medicines influencing a nervous system, lowering pressure, anti-gouty means, alcohol.

At a concomitant use of Baklosan with tricyclic antidepressants develops the expressed lowering of a muscle tone.

It is not necessary to accept Baklosan with karbidopy and a levodopa as confusion of consciousness and a hallucination can appear.

Terms of sale

Drug can be bought strictly according to the recipe.

Storage conditions

To protect from children. To store in the dry, dark place at a temperature no more than 25 degrees.

Period of validity

Three years.

Special instructions

Side effects of Baklosan often have a temporality, they need to be differentiated with symptoms of a basic disease.

At persons with a diabetes mellitus and diseases of a liver it is regularly recommended to control the level of transaminases, an alkaline phosphatase and glucose in blood.
The patients passing therapy by Baklosan should abstain from the occupations connected with increased by attention and reaction.

Baklosan's analogs

Coincidence on the ATH code of the 4th level:

Liorezal and Baclofenum – the main analogs of Baklosan.


  • Baklosan of 10 mg No. 50 of a tabletkipolfarm Pharmaceutical plant
  • Baklosan of 25 mg No. 50 of a tabletkipolfarm Pharmaceutical plant

Drugstore of IFC

  • Baklosan tbl 10 mg No. 50, Polpharmapolsha
  • Baklosan tbl 25 mg No. 50, Polpharmapolsha
to show still
Section: For a nervous system
in more detail

Education: Graduated from the Vitebsk state medical university majoring in "Surgery". At university headed Council of students' scientific society. Professional development in 2010 - in "Oncology" and in 2011 - in "A mammology, visual forms of oncology".

Experience: Work in an all-medical network 3 years the surgeon (The Vitebsk hospital of an emergency medical service, Lioznensky TsRB) and in combination the regional oncologist and the traumatologist. Work farm the representative within a year in the Rubicon company.

Provided 3 improvement suggestions on the subject "Optimization of an Antibioticotherapia depending on Species Composition of Microflora", 2 works took prizes in a republican competition review of student's scientific works (1 and 3 categories).
PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use Baklosan surely consult with the attending physician.