Baneotsin

Банеоцин Drug photo

The description is actual on 01.04.2016

  • Latin name: Baneocin
  • ATH code: D06AX
  • Active ingredient: Bacitracin + Neomycinum
  • Producer: Sandoz GmbH (Austria)

Structure

1 gram of powder includes 5000 ME sulfates of Neomycinum and 250 ME bacitracins of zinc.

In addition: as the powder sterilized basis (the corn starch including no more than 2% of magnesium oxide).

1 gram of ointment includes 5000 ME sulfates of Neomycinum and 250 ME bacitracins of zinc.

In addition: white soft paraffin and lanolin.

Release form

The remedy Baneotsin is made in the form of outside powder on 10 grams in polyethylene banks with the doser and in the form of ointment on 20 grams in a tuba.

Pharmacological action

Local bactericidal and antibacterial (wide range).

Pharmacodynamics and pharmacokinetics

Baneotsin is the antimicrobic combined remedy used only for topical (local) administration and including two antibacterial drugs which are characterized by the expressed bactericidal action in the structure.

Neomycinum represents the antibiotic aminoglycoside suppressing processes of synthesis of bacterial proteins. Activity of this antibacterial agent is shown concerning many gram-positive and gram-negative bacterial microorganisms.

Bacitracin belongs to group of the polypeptide antibiotics oppressing processes of replication of a bacterial cellular cover. The main antibacterial effect of this drug is observed concerning gram-positive microorganisms of the stafilokokk and streptococci representing a sort, and also concerning some gram-negative bacteria (resistance to bacitracin forms very seldom).

The synergism (the eaten-around action) of these two antibacterial drugs leads to significant increase in a therapeutic action spectrum of bacitracin and increase of its efficiency in relation to a number of microorganisms, in particular stafilokokk.

At local use of drug of absorption of its active ingredients, as a rule, it is not observed (even in case of drawing on the injured skin). Nevertheless, at the time of carrying out therapy in integuments find their high concentration.

This drug is characterized by good fabric tolerance in this connection its use on extensive skin sites can become the reason of system absorption.

Indications to use

Ointment use Baneotsin and powder Baneotsin is shown for the purpose of carrying out local therapy of infectious and inflammatory skin diseases which were caused by microorganisms, sensitive to active ingredients of drug, including:

  • prevention at newborns of an umbilical infection;
  • prevention of possible infectious complications after carrying out surgical (dermatological) manipulations, as additional therapy in the post-operational period after an epiziotomiya, cauterization, excision of fabrics, treatment of the becoming wet wounds, cracks and seams;
  • treatment of bacterial skin infections of local prevalence, including the infected trophic cankers of the lower extremities, contagious becoming wet the impetigo, the infected eczema, diaper bacterial dermatitis, including the bacterial complications caused by Varicella zoster and Herpes simplex.

Contraindications

It is forbidden to use any of dosage forms of drug at:

  • extensive skin defeats (because of risk of forming of the ototoksichesky effect which is shown a hearing loss);
  • personal hypersensitivity to Neomycinum, bacitracin or to other aminoglycosides;
  • the expressed disorders of secretory renal function (because of renal or heart failure);
  • the diagnosed pathologies of cochleovestibular system (in case of a possibility of system absorption of active ingredients of drug);
  • diseases of organs of sight.

Side effects

Ointment Baneotsin and powder Baneotsin, as a rule, is not led to emergence of any negative effects at their local use on small problem sites of integuments and mucous membranes from what ointment and powder of this medicine recommend to apply to treatment of local infectious diseases.

At long use the allergic manifestations including a xeroderma, reddening, skin rash / itch are possible. Mainly these phenomena proceed like contact eczema, in half of cases are provoked by a cross allergy to other aminoglycosides and are observed rather seldom.

Allow development of the system negative effects in most cases noted at treatment of extensive skin defeats when the high possibility of absorption of active ingredients of drug and emergence of its nephrotoxic and ototoksichesky action, and also disorders of neuromuscular conductivity is observed.

Application instruction of Baneotsin

Powder Baneotsin, application instruction

Drug in the form of powder is shown to use 2-4 times a day with its thin stratification on the struck skin sites.

In case of treatment of the burns occupying more than 20% of a body surface of the patient, powder can be used only once at 24 o'clock, in particular at the reduced renal function observed at the patient (in communication by possible absorption of active ingredients in a system blood stream).

At local use the maximum daily dosage of Neomycinum can make 1 gram that corresponds to use of 200 grams of powder a week. The repeated therapeutic course demands decrease in a week maximum dosage twice (to 100 grams).

Ointment Baneotsin, application instruction

Medicine in the form of ointment is allowed to use by 2-3 times a day for what ointment Baneotsin a thin layer is applied on affected areas of integuments. It is possible to practice putting ointment under the applied bandage.

Use of ointment in the post-operational period as an additional remedy is possible. Putting drug directly on bandage is preferable in case of local therapy of contaminated wounds and cavities (including the surgical scars which are dragging on second intention and bacterial infections of external acoustical pass without injury of a tympanic membrane).

Overdose

For this time of precedents of overdose at local use of Baneotsin it was not recorded.

Interaction

In case of a possibility of system absorption of active ingredients of drug parallel use of aminoglycosides or cephalosporins increases risk of forming of the nephrotoxic phenomena.

The combined Baneotsin's appointment with Furosemide or Acidum etacrynicum increases possibility of nephrotoxic and ototoksichesky reactions.

At observed system absorption sharing of Baneotsin with muscle relaxants, anesthetics and opioid analgetics can bring to development of neuromuscular blockade.

Cases of incompatibility of Neomycinum and bacitracin with other medical drugs are noted.

Terms of sale

Both let-out dosage forms of Baneotsin are allowed for nonprescription sale.

Storage conditions

The maximum temperature indicator of storage of ointment and powder Baneotsin is equal to 25 °C.

Period of validity

From the production moment: 2 years for powder and 3 years for ointment.

Special instructions

In case of use of the dosages of Baneotsin considerably exceeding recommended, because of possible absorption of its active ingredients it is necessary to pay attention to the negative symptomatology able to point to ototoksichesky or nephrotoxic reactions.

Due to the increase of risk of emergence of toxic effects at patients with observed pathologies of livers/kidneys it is necessary to appoint it, both prior to therapy, and during treatment, carrying out the analysis of urine and blood together with audiometric researches.

If during therapy allow a possibility of absorption of active ingredients of drug (at extensive skin damages), then there is a need of control over possible forming of symptomatology of neuromuscular blockade, in particular at patients with a heavy myasthenia, other neuromuscular pathologies, and also acidosis. In case of neuromuscular blockade recommend to appoint neostigmin or calcium drugs.

Long use of Baneotsin demands supervision over possible excessive increase in number of resistant microorganisms, sometimes with need of purpose of the corresponding therapy.

Long use of Baneotsin for treatment of children with pathologies of livers/kidneys, and also use of drug for processing of the extensive skin areas has to be coordinated with the doctor previously.

At emergence of superinfection or allergic manifestations therapy by Baneotsin has to be cancelled.

Analogs

Coincidence on the ATH code of the 4th level:

Analogs of ointment and powder Baneotsin are provided by the remedies used for topical administration (ointments, aerosols, cream, solutions):

Zdravzona

  • Baneotsin ointment 20gbiochemie GmbH
  • Baneotsin powder 10g flakonbiochemie GmbH
  • Baneotsin powder 10g a bottle with dozatorombiochemie GmbH

Drugstore of IFC

  • Baneotsin ointment of a tube of 20 g, Sandoz Gmbhavstriya
  • Baneotsin time naruzhn. fl 10 g, Sandoz Gmbhavstriya
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Apteka24

  • Baneotsinbiochemie (Austria)
  • Baneotsinmontavit (Austria)
  • Baneotsinmerck KGaA & Co. (Austria)

Paniapteka

  • Ointment baneotsin 20 g of a tube
  • Baneotsin time. 10gsandoz
Section: Antibiotics Dermatological Antimicrobic
in more detail

Education: Graduated from the Vinnytsia national medical university of N. I. Pirogov, pharmaceutical faculty, the higher pharmaceutical education – the specialty "Pharmacist".

Experience: Work in Koneks and Bios-Media pharmacy chains as "Druggist". Work as "Pharmacist" in Avicenna pharmacy chain of the city of Vinnytsia.

PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use Baneotsin surely consult with the attending physician.