M Baralginum

Баралгин М Drug photo

The description is actual on 19.01.2015

  • Latin name: Baralgin M
  • ATH code: N02BB02
  • Active ingredient: Metamizole sodium (Metamizole sodium)
  • Producer: AVENTIS PHARMA (India)

Structure M Baralginum

On MNN active ingredient – metamizole sodium.

Structure of tablets: 500 mg of metamizole sodium and additional components (magnesium stearate, macrogoal). 1 ml of solution contains 500 mg of active agent (in ampoules on 5 ml).

Release form M Baralginum

The tablets Baralginum are issued in blisters on 10 pieces. The box from a cardboard contains 1, 2, 5 or 10 blisters. Solution is issued in ampoules of 5 ml. In a pack — on 5 ampoules.

Pharmacological action

Active agent belongs to non-narcotic means and is derivative pyrazyl ketone. Medicine renders antipyretic, analgetic and slight antiinflammatory influence. In the main mechanism of action the medicine is similar to other non-narcotic analgesics.

Pharmacodynamics and pharmacokinetics

Active ingredient is hydrolyzed in a digestive tract, forming the active metabolite absorbed in hepatic system. Active component is capable to contact plasma proteins. The indicator the maximum concentration is registered in 120 minutes.

At patients with cirrhosis of various genesis time of semi-removal increases till 10 o'clock. Pricks Baralginum exceed the tableted form on time of occurrence of analgesic effect.

Indications to use of Baralginum

From what Baralginum helps? Most often the medicine is appointed for stopping of a pain syndrome of weak and average intensity:

The tablets Baralginum from what can be appointed still? The medicine is applied to removal of spasms of smooth muscle fabric:

Indications to use of Baralginum as a part of a combination therapy at infectious and inflammatory pathology:

Contraindications

  • the diseases accompanied with a bronchospasm;
  • bronchial asthma;
  • pregnancy;
  • deficit of enzyme dehydrogenase glyukozo-6-phosphate;
  • hepatic porphyria;
  • individual hypersensitivity;
  • the expressed pathology of hepatic system;
  • hemopoiesis pathology (neutropenia, agranulocytosis);
  • diseases of kidneys.

Relative contraindications:

Side effects

Application instruction of Baralginum of M (Way and dosage)

Tablets Baralginum, application instruction

The one-time dosage makes 500 mg. In days it is possible to take no more than 6 pill. As an anesthetic the medicine can be applied within 5 days, as antipyretic – 3 days. Unacceptably independent increase in a single dose. Tablets need to be washed down with water.

Baralginum pricks, application instruction

Solution in ampoules can be entered intramusculary and into a vein. A one-time dosage – 2-5 ml, daily – to 10 ml. Baralginum in/in is entered with a speed of 1 ml a minute (control of ChSS and level of a blood pressure is obligatory). Ampoules with solution before procedure warm to body temperature.

Overdose

  • spasms;
  • acute agranulocytosis;
  • nausea;
  • tachycardia;
  • falling of a blood pressure;
  • epigastric pains;
  • vomiting;
  • oliguria;
  • drowsiness;
  • paralysis of respiratory muscles;
  • hypothermia;
  • hemorrhagic syndrome;
  • disturbance of consciousness;
  • sonitus;
  • asthma.

The gastric lavage by means of a special probe is timely carried out, salt purgatives, enterosorbents are appointed. The hemodialysis and an artificial diuresis are recognized as effective. At registration of a convulsive syndrome intravenously enter high-speed barbiturates, such as Diazepam.

Interaction

Toxicity of a medicine increases at simultaneous therapy by oral contraceptives, tricyclic antidepressants and Allopyrinolum. Decrease in efficiency of drug is observed at treatment by inductors of microsomal enzymes (phenylbutazone, barbiturates).

Strengthening of expressiveness of negative reactions is observed at treatment by other non-narcotic analgesics. The analgetic effect of medicine amplifies at simultaneous therapy by sedative drugs. The expressed hyperthermia is observed at treatment by Fenotiazin's derivatives, Chlorpromazinum.

Unacceptably simultaneous treatment by Penicillin, introduction of colloid blood substitutes, X-ray contrast substances. Active component is capable to enter fight for communication with proteins at treatment by Indometacin, glucocorticosteroids, indirect anticoagulants. Propranolol, blockers of histamine receptors and Codeine strengthen effect of Metamizole sodium.

Terms of sale (the recipe in Latin)

Baralginum of M is released according to the recipe.

The tableted form:

Tab. Baralgini 500 mg
D.t.d N (the quantity of tablets is specified)
S. on 1 tab. at pains.

Pricks Baralginum:

Sol. Baralgini 5ml
D.t.d N (the number of ampoules is specified)
S. on 5 ml at pains.

Storage conditions

The producer recommends to store ampoules and tablets far from light, observing temperature condition of 8-28 degrees.

Period of validity

4 years.

Special instructions

To mix with other medicines in one syringe it is inadmissible. Perhaps temporary coloring of urine in a red shade (has no clinical value).

Analogs

Structural analogs:

Zdravzona

  • M Baralginum 500mg/ml solution for injections of 5 ml No. 5 of an ampulysanofa India Ltd.
  • Baralginum of M of 500 mg No. 100 of a tabletkisanofa India Ltd.
  • Baralginum of M of 500 mg No. 20 of a tabletkisanofa India Ltd.

Drugstore of IFC

  • M Baralginum solution for in 500mg/ml 5 ml No. 5, Aventis Pharma Ltdindiya
  • M Baralginum tbl Soteksrossiya No. 100, Aventis Pharma/
  • M Baralginum tbl No. 20, Hoechst Marion Roussel/Soteksrossiya
to show still
Section: Gastrointestinal Anesthetics
in more detail

Education: Graduated from the Bashkir state medical university majoring in "Medical business". In 2011 gained the diploma and the certificate in Therapy. In 2012 received 2 certificate and the diploma in "Functional diagnosis" and "Cardiology". In 2013 completed courses on "Topical issues of otorhinolaryngology in therapy". In 2014 completed advanced training courses in "A clinical echocardiography" and courses in "Medical rehabilitation".

Experience: From 2011 to 2014 the Policlinic No. 33 Ufa worked as the therapist and the cardiologist in MBUZ. Since 2014 the Policlinic No. 33 Ufa works as the cardiologist and the doctor of functional diagnosis in MBUZ.

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