Бифосин Drug photo

The description is actual on 18.06.2016

  • Latin name: Bifosine
  • ATH code: D01AC10
  • Active ingredient: Bifonazol
  • Producer: Synthesis of joint stock company (Russia)


In 100 ml or 100 g of medicine 1 g of active agent bifonazol contains.

In addition as a part of powder — zinc oxide, starch and talc; solution — poly(ethylene oxide); cream — poly(ethylene oxide)s and propylene glycol.

Release form

Is issued in the form of powder (powder), solution, spray, cream.

Pharmacological action

Antifungal drug.

Pharmacodynamics and pharmacokinetics

The main target of influence of a medicine is the component of a membrane of a fungal cell – ergosterol. Active component Bifonazol suppresses process of synthesizing of ergosterol at two stages of its forming that damages a cellular membrane of a fungal cell (functional and structural influence).

Bifosin is active concerning dermatophytes (fungicidal influence on epidermofiton, trikhofiton and a Microsporum), mold and drozhzhepodobny mushrooms (fungistatic influence). Medicine does not affect enterococci.

The minimum quantity of drug making effective antifungal impact makes 5 ng/ml. Concerning sort mushrooms Candida is observed fungicidal influence at concentration of drug of 20 ng/ml; in lower concentration the fungistatic effect is noted.

Indications to use

Medicine is appointed at multi-colored herpes, at a favus, a trichophytosis of pilar area of the head and smooth integuments, at a microsporia, erythrasmas, a tinea, an inguinal epidermophitia, mycotic defeats of brushes and feet.

Cream Bifosin is appointed at onychomycoses. The medicine is effectively applied at candidiasis of genitalias, integuments, nail plates, nail rollers, at a hyperhidrosis of feet and an interdigital intertrigo.


Bifonazol do not appoint at intolerance of lanolin, a tsetilstearol.

In the first trimester of pregnancy, and also to women during breastfeeding the medicine is appointed with care.

Side effects

The application instruction of Bifosin contains the following side effects: contact dermatitis, feeling of heat and burning in the place of use, a hyperemia, allergic reactions, a peeling or maceration of skin, irritation, local reactions in the field of a nail bed.

Application instruction of Bifosin (Way and dosage)

Apply for the night once a day.

Treatment of mycosis of interdigital intervals and feet takes about 3 weeks, at mycotic defeats of brushes, a body and folds antifungal therapy is carried out within 2-3 weeks. At an erythrasma, multi-colored herpes the medicine is appointed to 2 weeks, at candidiasis of integuments (a superficial form) bifonazol applied 2-4 weeks.

Cream Bifosin, application instruction

Put 1 time a day with a thin layer (it is desirable before going to bed) at defeat of integuments of feet, brushes and folds. The therapy course in many respects depends on the area of defeat, localization of a disease and the main activator.

Processing of a site by the square about a palm requires about 0,5-1 centimeter of a strip of cream.

At an onychomycosis cream is applied on all nail plate with a thin layer then cover with a plaster or a bandage for days. Before change of a bandage the finger is recommended to be placed in warm water for 10 minutes. The softened infected part of a nail plate is deleted by means of a special scraper. The nail is dried up and repeatedly apply cream, closed a plaster. The course is counted on full removal of an affected area of a nail plate. At emergence of irritation integuments around a nail process zinc paste.

The instruction on solution

Bifosin is recommended to rub solution the accurate movements. Processing of a site by the square about a palm requires about 3 drops of solution.

Bifosin is more preferable to appoint solution to processing of pilar area of the head (previously it is recommended to shave an affected area). Duration of antifungal therapy – 1 month. After subsiding inflammatory reactions continue treatment by purpose at first of cream, and then powders.

Powder use

Therapy of a hyperhidrosis is carried out by powder Bifosin within 2-3 weeks. At positive dynamics transition to a cream form of drug (10-15 days) is recommended.

Spray use Bifosin

It is necessary to humidify affected areas of an integument enough.


It is almost impossible.

Terms of sale

The recipe is not required

Storage conditions

In the place, dry, dark, unavailable to children, at a temperature of 15-25 degrees Celsius.

Period of validity

2 years.

Special instructions

At insufficient efficiency of antifungal therapy additional inspection of the patient (an assessment of endocrine and immune systems, a condition of microcirculation of a zone of defeat) is required. Correction of therapy by results of the conducted examination is obligatory. To babies powder Bifosin is appointed in exceptional cases and under obligatory control of the treating doctor. At treatment of an onychomycosis careful removal of the damaged site of a nail plate is important. The enclosed plasters cannot be reused. Bifosin can buy in a drugstore (the prescription form is not required).

Bifosin's analogs

It is possible to call: Bifonazol, Mikospor, Bifasam.

About Bifosin

From a fungus of nails this drug helps quickly enough. About spray and other forms of this medicine confirm high performance of a medicine in therapy of fungus diseases.


  • Bifosin of 1% 30 g kremsintez joint stock company
  • Bifosin of 1% 20 ml spreysintez joint stock company

Drugstore of IFC

  • Bifosin spray of 1% 20 ml, Synthesis of AKO of joint stock company (Kurgan) Russia
  • Bifosin cream of 1% 30 g, Synthesis of AKO of joint stock company (Kurgan) Russia
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Section: Antifungal
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Education: Graduated from the Bashkir state medical university majoring in "Medical business". In 2011 gained the diploma and the certificate in Therapy. In 2012 received 2 certificate and the diploma in "Functional diagnosis" and "Cardiology". In 2013 completed courses on "Topical issues of otorhinolaryngology in therapy". In 2014 completed advanced training courses in "A clinical echocardiography" and courses in "Medical rehabilitation".

Experience: From 2011 to 2014 the Policlinic No. 33 Ufa worked as the therapist and the cardiologist in MBUZ. Since 2014 the Policlinic No. 33 Ufa works as the cardiologist and the doctor of functional diagnosis in MBUZ.

PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use Bifosin surely consult with the attending physician.