Bilobil

Билобил Drug photo

The description is actual on 30.01.2015

  • Latin name: Bilobil
  • ATH code: N06DX02
  • Active ingredient: Ginkgo bilobed leaves extract (Ginkgo Bilobae foliorum extract)
  • Producer: KRKA (Slovenia)

Structure

  • One capsule of means Bilobil includes 40 mg of extract from leaves of a tree of a bilobed ginkgo.
  • One capsule of means Bilobil Forte includes 80 mg of extract from leaves of a tree of a bilobed ginkgo.
  • One capsule of means Bilobil Intens 120 includes 120 mg of extract from leaves of a tree of a bilobed ginkgo.

100 mg of extract include 19.2 mg of glycosides of a ginkgo of flavonovy type and 4.8 mg of lactones of terpenic type (a bilobalida and a ginkgolida).

Additional substances: colloid silicon oxide, corn starch, monohydrate of lactose, magnesium stearate, talc.

Structure of a cover: dye red iron oxide, titanium dioxide, azoruby, dye black iron oxide, gelatin.

Release form

Pink gelatinous capsules, brown powder with visible dark particles contains inside. 10 capsules in the blister, two or six blisters in a pack from a cardboard.

Pharmacological action

The neurometabolic, antigipoksantny, improving microcirculation, strengthening peripheric and cerebral circulation, angioprotektivny, antioxidant action.

Pharmacodynamics and pharmacokinetics

Pharmacological

Phytodrug, normalizes a metabolism in cells, rheological indicators of blood and perfusion of fabrics.

Improves cerebral blood circulation and provides a brain with glucose and oxygen, slows down aggregation of erythrocytes, suppresses activation of thrombocytes. Has the dozozavisimy regulating action on vascular system, activates development of NO, expands a gleam of arterioles, raises a tone of veins, changing thereby filling by blood of vessels. Weakens permeability of a wall of vessels. Possesses antitrombotichesky action (strengthens membranes of erythrocytes and thrombocytes, influences biosynthesis of prostaglandins, weakens effects of a platelet activating factor). Slows down peroxide oxidation of fats of cellular membranes and education of free radicals. Normalizes a metabolism of neuromediators (such as dopamine, noradrenaline and acetylcholine). Also has anti-hypoxemic effect, stimulates a metabolism, promotes accumulation of makroerg, accelerates utilization of glucose and oxygen, regulates media even processes in a head brain.

Pharmacokinetics

After reception bioavailability of a bilobalid and ginkgolid makes 85%. The greatest concentration is fixed in two hours after the drug use. Semi-removal time – 4-10 hours. Molecules of these substances do not break up in an organism and are completely evacuated with urine, to a lesser extent – with a stake.

Indications to use

  • Disturbance of microcirculation and peripheric circulation, Reynaud's syndrome.
  • The Distsirkulyatorny encephalopathy because of a stroke, injuries, age and other reasons which is followed by easing of memory, attention, decrease in cognitive abilities, change of a sleep pattern.
  • Neurosensory disturbances (sonitus, dizziness, gipoakuziya and others).
  • Diabetic pathology of a retina.
  • Age degeneration of a macula lutea.

Contraindications

Side effects

  • Reactions from nervous activity: sleeplessness, headache, hearing disorder, dizziness.
  • Allergic reactions: hyperemia, swelling, itch.
  • Reactions from digestion: vomiting, nausea, diarrhea.
  • Other reactions: deterioration in coagulability of blood.

Application instruction (Way and dosage)

Capsules of drug should be swallowed completely, washing down with water. Before reception it is recommended to consult with the doctor. Noticeable signs of improvement of a state can appear in 1 month of treatment. Duration of treatment should not be less than three months.

Capsules (tablet) Bilobil, application instruction

At distsirkulyatorny encephalopathy use 1-2 capsules three times a day.

At treatment of disturbances of microcirculation and peripheric circulation, Reynaud's syndrome accept on 1 capsule three times a day.

At a diabetic retinopathy, neurosensory disturbances, recommend to an age degeneration of a macula lutea on 1 capsule three times a day.

Application instruction Bilobil Forte and Bilobil Intens 120

Bilobil Forte use usually on 1 capsule twice or three times a day, and Bilobil Intens 120 accept on 1 capsule of 1 times (morning) or 2 times (in the morning and in the evening) in day.

Overdose

There are no messages on the recorded overdose cases.

Interaction

Use of drug is not recommended to the patients who are regularly using the anticoagulants, non-steroidal anti-inflammatory drugs and other drugs lowering coagulability of blood as similar combinations increase risk of emergence of bleedings because of increase in duration of coagulation.

Terms of sale

Without recipe.

Storage conditions

  • To protect from children.
  • To store at a temperature up to 25 degrees.

Period of validity

Three years.

Special instructions

Before an operative measure it is necessary to inform the doctor on administration of drug.

At repeated development of a sonitus and dizziness, sudden deterioration in hearing it is necessary to consult urgently with the doctor.

Drug contains lactose and a dextrose therefore persons should not appoint it with deficit of lactase, a sprue of glucose or a galactose.

Drug contains E122 dye or an azoruby which is capable to cause emergence of a bronchospasm and other allergic reactions.

During reception of means it is recommended to be careful during the driving or work with mobile mechanisms.

Analogs

Bilobil's analogs: Vitrum Memori (tablets), Ginos (tablet), Ginkgo Biloba (capsule), Memoplant (tablet), Gingium (tablets), Ginkoum (capsules), Tanakanum (tablets, peroral solution).

Zdravzona

Drugstore of IFC

  • Bilobil forte kaps 80 mg No. 60, Krkasloveniya
  • Bilobil kaps 40 mg No. 20, Krkasloveniya
  • Bilobil kaps 40 mg No. 60, Krkasloveniya
  • Bilobil intens 120 kaps 120 mg No. 60, Krkasloveniya
  • Bilobil intens 120 kaps 120 mg No. 20, Krkasloveniya
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Apteka24

  • Bilobil forte capsules 80 mg No. 20KPKA (Slovenia)
  • Bilobil of a capsule 40 mg No. 60KPKA (Slovenia)
  • Bilobil forte capsules 80 mg No. 60KPKA (Slovenia)
  • Bilobilkrka (Slovenia)
  • Bilobil intens20

Paniapteka

  • Bilobil kaps. 40 mg No. 20KPKA
  • Bilobil kaps. 40 mg No. 20KPKA
  • Bilobil kaps. 40 mg No. 20KPKA
  • Bilobil kaps. 40 mg No. 20KPKA

BIOSPHERE

  • Bilobil Intens of 120 mg No. 60 kaps.
  • Bilobil forte 80 mg No. 20 kaps.
  • Bilobil forte 80 mg No. 60 kaps.
  • Bilobil of 40 mg No. 20 kaps.
  • Bilobil of 40 mg No. 60 kaps.
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Section: Dietary supplements For a nervous system
in more detail

Education: Graduated from the Vitebsk state medical university majoring in "Surgery". At university headed Council of students' scientific society. Professional development in 2010 - in "Oncology" and in 2011 - in "A mammology, visual forms of oncology".

Experience: Work in an all-medical network 3 years the surgeon (The Vitebsk hospital of an emergency medical service, Lioznensky TsRB) and in combination the regional oncologist and the traumatologist. Work farm the representative within a year in the Rubicon company.

Provided 3 improvement suggestions on the subject "Optimization of an Antibioticotherapia depending on Species Composition of Microflora", 2 works took prizes in a republican competition review of student's scientific works (1 and 3 categories).
PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use Bilobil surely consult with the attending physician.