Dermosolonum

Дермозолон Drug photo

The description is actual on 14.07.2016

  • Latin name: Dermosolon
  • ATH code: D07BA01
  • Active ingredient: Kliokhinol + Prednisolonum (Clioquinol + Prednisolone)
  • Producer: Gedeon Richter Ltd. (Hungary)

Structure

Prednisolonum, kliokhinol, cetyl alcohol, methylparahydroxybenzoate, polysorbate, liquid paraffin, vaseline, wax.

Release form

Ointment for external use of 5 g of yellowy-brown color of a homogeneous consistence in a polyethylene tuba in a cardboard pack.

Pharmacological action

Antifungal, antiinflammatory, antiseptic, antiallergic, antipruritic.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

The drug having antiinflammatory, antifungal, antiallergic, antiseptic and antipruritic effect.

Locally Prednisolonum which is a part of ointment Dermosolonum narrows vessels and reduces permeability of a vascular wall, reduces braking of proliferation of fibroblasts and migration of monocytes in the inflammation center, interfering with its distribution, stabilizes lizosomalny membranes. Influences alternative and exudative phases of an inflammation, interferes with its distribution.

Kliokhinol is antimicrobic means for external use, destroys fermental system of mushrooms and microbes. Possesses activity concerning gram-positive bacteria (stafilokokk, enterococci), dermatophytes and barmy mushrooms.

Pharmacokinetics

At topical administration of ointment, as a result of Prednisolonum absorption, actively active ingredient in insignificant quantity gets to a system blood stream. In blood Prednisolonum is in the connected view with albumine and transcortinum. Biotransformation of Prednisolonum occurs in a liver by oxidation, and the oxidized forms are sulphated and glyukuronizirutsya. The part — in the form of metabolites through kidneys and intestines is removed partially in not changed look, and.

Kliokhinol at external use in insignificant quantity comes to a system blood stream where contacts blood proteins. It is metabolized partially in a liver and removed with urine.

Indications to use

The dermatitis of various genesis complicated by a fungal or bacterial infection, the bacterial eczema including for the second time infected, interdigital mycosis, superficial infections of skin.

Contraindications

Hypersensitivity to drug, a tuberculosis cutis, chicken pox, syphilis, skin postvaccinal reactions, dermatitis, damages of an integument, a new growth and precancerous diseases of skin.

Side effects

Drug when using in the recommended dosages is transferred by patients well. However, when putting drug on big sites of skin or prolonged use of use there can be side effects: an inflammation of sebaceous glands and appearance of steroid eels, purpuras, teleangiectasias, dryness, irritation, burning a skin itch, hypersensitivity to iodine.

Dermosolonum, application instruction (Way and dosage)

Drug is used outwardly.

It is recommended to apply on an affected area of skin with a thin layer 1-3 times a day.

Overdose

About cases of overdose it was not reported.

Interaction

Clinically expressed interaction symptoms with other medicines are not known.

Terms of sale

It is released without recipe of the doctor.

Storage conditions

Temperature of storage is up to 15 °C.

Period of validity

2 years.

Analogs of Dermosolonum

Coincidence on the ATH code of the 4th level:

Drugs the analogs containing active ingredient kliokhinol: Lorindenm With (kliokhinol + Flumethasonum), Synalarum To (kliokhinol + fluotsinolon-acetonide). The ointments containing hormonal drug and antifungal Mycosolonum (Miconazolum + mazipredon), Candide B (Clotrimazolum + betamethasone).

About Dermosolonum

Corticosteroids do not possess antimicrobic and antifungal action. But often there is an accession of consecutive infection at eczemas, an ekzemopodobny dermatosis, neurodermatitises, an intertrigo. In the pharmaceutical market there are topical steroid drugs combined — added with medicines with antibacterial and fungicidal action that considerably expands possibilities of use and raises a therapeutic effectiveness. In such cases ointment Dermosolonum is applied. All ointments containing hormones have fast effect and are very effective. This fact is reflected in responses of patients:

  • "… High-speed ointment, rather inexpensive, effective";
  • "… Me appoint Dermosolonum for a short time. The doctor always warns what long cannot be applied. And it is not necessary — the inflammation, an itch, irritation quickly disappears".

Many patients are upset with the fact that recently it is impossible to buy this drug:

  • "… Remarkable drug, but unfortunately, cannot be bought it now";
  • "… Long ago on sale Dermosolonum disappeared. Tried other ointments — do not help";
  • "… Several years used this ointment — very well helped. Now it disappeared in drugstores. At Lorindenm About effect it is much worse".

It is necessary to know that ointments with glucocorticoids cannot independent be used by patients on the advice of the friends, neighbors or relatives. The hobby for these drugs without indications and implementation of rules of their use can do more harm, than advantage. They can be appointed only specialists.

Section: Dermatological
in more detail

Education: Graduated from Sverdlovsk medical school (1968 - 1971) as "Paramedic". Graduated from the Donetsk medical institute (1975 - 1981) as "An epidemiologist, a hygienist". Passed postgraduate study in the Central scientific research institute of epidemiology Moscow (1986 - 1989). An academic degree – the candidate of medical sciences (degree is awarded in 1989, protection – the Central scientific research institute of epidemiology Moscow). Numerous advanced training courses are studied in epidemiology and infectious diseases.

Experience: Work as the manager of department of disinfection and sterilization of 1981 - 1992. Work as the manager of department of especially dangerous infections of 1992 - 2010. Teaching activity at Medical institute 2010 - 2013.

PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use Dermosolonum surely consult with the attending physician.