Diabeton

Диабетон Drug photo

The description is actual on 26.12.2015

  • Latin name: Diabeton
  • ATH code: A10BB09
  • Active ingredient: Gliklazid
  • Producer: Les Laboratoires Servier Іndustrie (France)

Structure

1 tablet contains 80 mg of active agent gliklazid.

Release form

Is issued in the tableted form.

Pharmacological action

Possesses hypoglycemic action.

Pharmacodynamics and pharmacokinetics

The main, actively active ingredient – gliklazid. Hypoglycemic drug from group of a sulfonilmochevina of the second generation. Gliklazid is derivative sulfonilmochevina. Contains an azobitsiklooktanovy ring that considerably distinguishes the mechanism of its action from sakharosnizhayushchy guanyl guanidines and sulfonamides.

Drug also has haemo vascular, metabolic and antioxidant effect. Under the influence of Diabeton concentration of glucose in blood decreases (blagodaryausilenny production of insulin special beta cells of a pancreas).

At patients with a diabetes mellitus of the second type drug returns early peak of production of insulin, and raise the subsequent phase of an insulinosekretion. Increase of concentration of insulin happens before meal or loading of glucose.

Antioxidant and haemo vascular actions of HP reduce risk of complications of SD. Diabeton prevents microthrombosis thanks to partial inhibition of aggregation, adhesion of thrombocytes, decrease in number of markers of activation of thrombocytes.

Drug increases activity of tPa, influences fibrinolitic activity of an endothelial vascular wall.

The antioxidant effect of a glycoside is reached thanks to decrease in concentration of peroxide lipids in a blood plasma, to increase of activity of dismutase of erythrocytes, plasma thiols, increase in the general antioxidant capacity.

Gliklazid is metabolized in a liver.

Indications to use

Diabetes mellitus of the second type (at inefficiency of the program and a diet on weight reduction).

Contraindications

Diabetic ketoacidosis, diabetes mellitus of the first type, heavy pathology of renal and hepatic systems, diabetic prekoma, coma, pregnancy.

With care Diabeton appoint to elderly persons, after extensive burns. It is not applied in pediatrics.

Side effects

At an inadequate diet, disturbance of the mode of dosing the hypoglycemia, feeling of hunger, fatigue, headaches, perspiration, tachycardia, sleeplessness, uneasiness, aggression, a carelessness, vision disorders, paresis, a tremor, a depression, a carelessness, aphasia, touch disturbances, a delirium, a hypersomnia, spasms is noted.

Gastrointestinal tract: dispepsichesky frustration, cholestatic jaundice, loss of appetite, increase of level of liver enzymes.

Bodies of a hemopoiesis: oppressions of function of a marrowy hemopoiesis.

Allergy.

Tablets Diabeton, application instruction (Way and dosage)

According to the application instruction, medicine is taken inside during meal. An initial dose – 80 mg a day, average – 160-320 mg.

The dosage is selected individually. Diabeton's dose depends on disease severity, age, sugar level in blood.

Overdose

Disturbances of consciousness, hypoglycemia, coma.

It is necessary to enter 40% hypertonic salt solution of a dextrose, to accept inside sugar, 2 mg of a glucagon.

To carry out control of blood on sugar each 15 minutes. To eat food carbohydrate-rich (digestible).

At wet brain appoint dexamethasone, Mannitolum.

Interaction

Blockers of H2-histamine receptors, APF, NPVS inhibitors, fibrata, antifungal drugs, anticoagulants of a coumarinic row, MAO inhibitors, anabolic steroids, streptocides, guanyl guanidines, cyclophosphamides, pentoksifillin, theophylline, tetracycline, Reserpinum, Disopyramidum, insulin, ethanol, Allopyrinolum strengthen Diabeton's action.

GKS, barbiturates, antiepileptic, adrenostimulyator, BMKK, thiazide diuretics, Triamterenum, furosemide, Baclofenum, diazoxide, asparaginase, Triamterenum, morphine, an isoniazid, terbutalin, Ritodrinum, a glucagon, salbutamol, rifampicin, estrogen, Chlorpromazinum, niacin weaken effect of drug.

Terms of sale

The recipe is required.

Storage conditions

In the place, unavailable to children, at a temperature no more than 30 degrees Celsius.

Period of validity

No more than three years.

Special instructions

At a diabetes decompensation, surgical interventions it is necessary to consider insulin reception. At the use of ethanol the risk of development of a hypoglycemia increases.

At an emotional, physical overstrain it is necessary to carry out drug dose adjustment Diabeton.

Elderly people, patients with pituitary and adrenal insufficiency are especially sensitive to hypoglycemic HP.

Slows down the speed of psychomotor reactions.

MNN: Gliklazid.

Diabeton's analogs

Analogs of drug it is possible to call means: Glidia, Glikinorm, Gliklada, Gliklazid, Glioral, Diaglizid, Diazid, Panmikron, Reklid.

That it is better: Maninil or Diabeton?

Maninil schitatatsya by more harmful drug.

Zdravzona

  • Diabeton of MV of 30 mg No. 60 tabletkiservier
  • Diabeton of MV of 60 mg No. 30 tabletkiservier
  • Fitodiabeton tea No. 20 filter-paketyzdorovye of the nation of NPP LLC

Drugstore of IFC

  • Tea Fitodiabeton f / pack ice of 2 g No. 20, Health of the nation (Moscow) Russia
  • Diabeton of MV tbl with a modifits.vysvobozhdeniye of 60 mg No. 30 **, Ooorossiya's Servier/Serdiks
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Apteka24

  • Diabeton MR30

BIOSPHERE

  • Diabeton MR of 30 mg No. 60 of the tab. Servier (France)
  • Diabeton MR of 60 mg No. 30 of the tab. of Servier (Ireland) Industries Ltd, reg. ud. Les Laboratoires Servier, France (Ireland)
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Section: Diabetic
in more detail

Education: Graduated from the Bashkir state medical university majoring in "Medical business". In 2011 gained the diploma and the certificate in Therapy. In 2012 received 2 certificate and the diploma in "Functional diagnosis" and "Cardiology". In 2013 completed courses on "Topical issues of otorhinolaryngology in therapy". In 2014 completed advanced training courses in "A clinical echocardiography" and courses in "Medical rehabilitation".

Experience: From 2011 to 2014 the Policlinic No. 33 Ufa worked as the therapist and the cardiologist in MBUZ. Since 2014 the Policlinic No. 33 Ufa works as the cardiologist and the doctor of functional diagnosis in MBUZ.

PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use Diabeton surely consult with the attending physician.