Dibazolum

Дибазол Drug photo

The description is actual on 14.06.2016

  • Latin name: Dibazol
  • ATH code: C04AX31
  • Active ingredient: Bendazolum (Bendazol)
  • Producer: SISHUI XIERKANG PHARMACEUTICAL (China), FARM OZONE (Russia), MEDICAL DRUGS BORISOVSKY PLANT (Republic of Belarus), BIOSYNTHESIS (Russia), BIOCHEMIST (Russia), MOSCOW PHARMACEUTICAL FACTORY (Russia), FARMSTANDART-UFIMSKIY VITAMIN PLANT (Russia) and others.

Structure

The tablet contains 20 mg of Bendazolum (on MNN) and auxiliary components (the tablet for children contains only 4 mg of active agent).

1 ml of solution contains 5/10 mg of Bendazolum.

Medicine formula: C14-H12-N2 (a source — Wikipedia). It is considered that appropriate quality of medicinal medicines and substances is provided due to observance of the requirements and norms established by the GMP standards. The state pharmacopeia has validity and is under the state control.

Release form

Tablets are packed into bezjyacheykovy planimetric packaging on 10 pieces. Similar packaging at the tablets applied in pediatric practice.

Solution is issued in ampoules of 2 ml. In a pack from a cardboard there are 10 ampoules.

Pharmacological action

Active component renders spasmolytic, myotropic, vasodilating and short hypotonic actions. Active ingredient exerts impact on smooth muscles of vessels of internals, influences venules and arterioles. Medicine is capable to reduce a tone of blood vessels, reducing a blood pressure and strengthening inflow of blood to those sites of a myocardium which suffer from ischemia and a hypoxia that is observed at an ischemic heart disease.

Bendazolum is capable to stimulate synoptic interneural transfer in a spinal cord that allows to apply a medicine in neurologic practice. Active component also exerts immunomodulatory impact since it is similar to Levamisole which belongs to group of the medicines stimulating immune processes. The immunopromoting effect of drug is explained by ability of Bendazolum to strengthen development of an endogenous form of interferon.

Pharmacodynamics and pharmacokinetics

Good absorption from a gleam of a digestive tract is characteristic of a medicine. As a result of a metabolism 2 main active metabolites are formed. The therapeutic effect is registered in 30-60 minutes and can proceed till 3 o'clock. The preferential way of removal of medicine – through renal system, small part of metabolites is removed by intestines.

Indications to use of Dibazolum

Bendazolum is appointed to patients who suffer from spasms of smooth muscle fabric of vessels. The medicine can be applied to stopping of hypertensive crisis. At a spasm of smooth muscles of internals (intestinal colic, a peptic ulcer, pancreatitis, cholecystitis) due to relaxation of muscles expressiveness of a pain syndrome decreases.

Indications to use of Dibazolum in neurology:

  • syndrome of sluggish paralysis;
  • paralysis of a facial nerve;
  • treatment of the residual phenomena of poliomyelitis.

From what tablet?

The tableted form found broad application in medical practice: cardiology, neurology, therapy, gastroenterology.

Dibazolum from what helps?

The medicine helps to reduce pressure, to remove spasms and to reduce expressiveness of the pain syndrome which arose against a spazmirovannost of smooth muscle fabric.

Contraindications

Dibazolum of UBF is not appointed at individual hypersensitivity to Bendazolum. In pediatric practice tablets with a dosage of 20 mg of active agent are not applied.

Purpose of a medicine is not recommended to patients who have arterial hypotonia, a peptic ulcer of a digestive tract with bleedings, at pathology of renal system.
Purpose of Bendazolum to the persons suffering from a diabetes mellitus, heart failure (a heavy current) is inadmissible at the tone lowered muscular.

Advanced age (belongs to relative contraindications especially at prolonged use). With care appoint to persons whose work requires special attention and concentration since the incoordination and dizzinesses is possible during treatment.

Side effects

Good tolerance is characteristic of Dibazolum, the changes on the electrocardiogram connected with change of fraction of emission of a left ventricle seldom are registered. At predisposed persons allergic answers, arterial hypotonia, dizzinesses can be registered. At administration of the drug Dibazolum in/in perhaps development of a pain syndrome in the field of an injection.

Application instruction of Dibazolum (Way and dosage)

Tablets Dibazolum, application instruction: on 20-50 mg 2-3 times a day within 3-4 weeks. To children appoint 1-5 mg of times a day, the dosage varies depending on age.

The application instruction of Dibazolum of UBF in neurologic practice: 5 mg a day every other day, a course of 5-10 days. Treatment is repeated in 3-4 weeks. Further courses it is possible to spend each 1-2 months.

Dibazolum in ampoules in a dose of 30-40 mg is applied to stopping of hypertensive crisis. Injections can be given intramusculary or intravenously. At substantial increase of a blood pressure and an exacerbation of an arterial hypertension 2-3 times a day intramusculary enter 20-30 mg of Bendazolum. The course is expected 8-14 days.

Overdose

At reception of the doses exceeding recommended by the producer the negative symptomatology is registered:

The specific antidote is not developed therefore first aid at poisoning is directed to reduction of absorption of active drug from a gleam of a digestive tract by a call of vomiting, a gastric lavage and purpose of such enterosorbiruyushchy medicines as Smekta, Absorbent carbon, Polisorb and others. At development of other clinical picture step-by-step posindromny therapy is carried out.

Interaction

Strengthening of expressiveness of anti-hypertensive effect at simultaneous use with diuretic medicines and anti-hypertensive means is registered. Bendazolum is capable to prevent the increase in OPSS caused by reception of beta adrenoblockers. The hypotensive effect of Dibazolum amplifies at Phentolamine reception.

Terms of sale

Dibazolum can be got in a drugstore, having shown the form with medical appointment or the recipe in Latin:
Rp.: Tab. Dibazoli 0.02
D.t.d. N10 in tabul.
S. according to the scheme.

Storage conditions

Solution and tablets are stored in original packaging far from direct sunshine. The temperature condition recommended by the producer – to 30 degrees.

Period of validity

Solution can be stored within 4 years, and a tablet – 5 years.

Special instructions

It is not applied to prolonged treatment of an idiopathic hypertensia, especially at elderly people.

Analogs

Coincidence on the ATH code of the 4th level:

Structural analogs are not developed.

Zdravzona

  • Dibazolum of 20 mg No. 10 tabletkiuralbiofarm joint stock company
  • Dibazolum of 1% solution for injections of 1 ml No. 10 ampulydalkhimfarm joint stock company
  • Dibazolum of 1% solution for injections of 5 ml No. 10 ampulybiokhimik joint stock company
  • Dibazolum of 0,5% 2 ml No. 10 of amp.

Drugstore of IFC

  • Dibazolum tbl 20 mg No. 10, Moscow FF (г.Москва) Russia
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Apteka24

  • Dibazoldarnitsa (Ukraine, Kiev)
  • Dibazoldarnitsa (Ukraine, Kiev)
  • Dibazollugansky HFZ (Ukraine, Luhansk)
  • Dibazoldarnitsa (Ukraine, Kiev)

Paniapteka

  • Dibazolum solution for infection. 1% of amp. 1 ml No. 10darnitsa
  • Dibazolum solution for infection. 1% of amp. 1 ml No. 10darnitsa
  • Dibazolum solution for infection. 1% of amp. 1 ml No. 10darnitsa
  • Dibazolum solution for infection. 1% of amp. 1 ml No. 10darnitsa

BIOSPHERE

  • Dibazolum of 1%/5 ml No. 5 solution for in.amp.
  • Dibazolum of 0,5%/2 ml No. 10 solution for in.amp. Borisovsky ZMP (Belarus)
  • Dibazolum of 20 mg No. 10 of table.
  • Dibazolum of 1%/2 ml No. 10 solution for in.amp.
  • Dibazolum of 1%/5 ml No. 10 solution for in.amp. Darnitsa (Ukraine)
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Section: Gastrointestinal Cardiological Cardiovascular
in more detail

Education: Graduated from the Bashkir state medical university majoring in "Medical business". In 2011 gained the diploma and the certificate in Therapy. In 2012 received 2 certificate and the diploma in "Functional diagnosis" and "Cardiology". In 2013 completed courses on "Topical issues of otorhinolaryngology in therapy". In 2014 completed advanced training courses in "A clinical echocardiography" and courses in "Medical rehabilitation".

Experience: From 2011 to 2014 the Policlinic No. 33 Ufa worked as the therapist and the cardiologist in MBUZ. Since 2014 the Policlinic No. 33 Ufa works as the cardiologist and the doctor of functional diagnosis in MBUZ.

PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use Dibazolum surely consult with the attending physician.