Ekobol

Antibiotic. Active component – amoxicillin. The principle of influence is directed to transpeptidase inhibition, to suppression of development of a peptidoglikan (an important component of a cell wall) during growth and division that causes death of a bacterial cell. The medicine works bakteritsidno. The microorganisms capable to develop a penicillinase are steady against active component. Medicine influences on a salmonella, shigellas, neysseriya, streptococci, aerobic gram-positive strains, gram-negative bacteria, staphylococcus. As a bifidogenny factor in drug lactulose (polysaccharide of a synthetic origin) in which molecule there are remains of fructose and a galactose is used. This polysaccharide is not capable to be soaked up independently from a stomach and upper parts of a digestive tract therefore lactulose is not hydrolyzed. Ekobol contains polysaccharide which stimulates development and growth of lactobacilli and bifidobacteria. Under action of a medicine formation of organic acids in a gleam of a large intestine amplifies. Acetic, milk, ant acids suppress development of pathogenic flora in intestines, and reduce absorption of toxic nitrogen-containing substances. Thus, polysaccharide lactulose, protects intestinal microflora from harmful influence of antibacterial substance of an amoksifillin. Ekobol can buy in the form of tablets (dosages: 125, 250 and 500 mg). In the blister of 20 tablets. The price of Ekobol depends on a dosage, the region, pharmacy chain.

Indications:

Ekobol appoint at infectious defeats. Diseases of a digestive tract: cholangitis, typhoid, coloenteritis, cholecystitis. Diseases of an urinary path: cervicitis, pyelitis, gonorrhea, urethritis, endometritis, cystitis. Diseases of respiratory system, ENT organs: pneumonia, sinusitis, tonsillitis, average otitises, bronchitis, pharyngitises. The application instruction of drug Ekobol recommends to appoint a medicine at a hay fever, the impetigo, an ugly face, a dermatosis of infectious genesis, at borreliosis, listeriosis, salmonellosis, dysentery. The medicine is appointed for prevention of an endocarditis.

Contraindications:

Ekobol is contraindicated at a pollinosis, bronchial asthma, allergic diathesis, at hypersensitivity to amoxicillin, cephalosporins, penicillin, karbapenema. Medicine is not appointed at a lymphoid leukosis, an infectious mononucleosis, feeding a breast, at the colitis caused by reception of antibiotics. Drug is not appointed to children till 3 years. At an allergy, tendencies to bleedings, diseases of kidneys and incubation of pregnancy Ekobol appoint after approval of several specialists.

Side effect:

Nervous system: changes in behavior, uneasiness, ataxy, excitement, depression, spasms, peripheral neuropathy, confusion of consciousness, headaches, dizzinesses. Digestive tract: perversion of flavoring perception, nausea, dysbacteriosis, glossitis, stomatitis, increase of level of ALT, nuclear Heating Plant enzymes, vomiting, pseudomembranous coloenteritis, diarrhea. System of a hemopoiesis: neutropenia, decrease in number of leukocytes, anemia, Werlhof's disease. Allergic answers: rhinitis, hypostasis, an erythema, a hyperemia, exfoliative dermatitis, an eosinophilia, a dermahemia, it is rare – an anaphylaxis. Tachycardia, superinfection (is possible at an immunodeficiency), vagina candidiasis, intersticial nephrite. Responses on Ekobol indicate good tolerance of drug at reception of tablets to or after food.

Overdose:

It is shown by diarrhea, disturbance of water and electrolytic balance, vomiting and nausea. The gastric lavage, reception of salt purgatives, recovery of water and electrolytic balance is required. Good results are shown by a hemodialysis.

Route of administration:

Ekobol accept inside. The recommended scheme: three times a day on 500 mg. In hard cases appoint 750-1000 mg to reception. Treatment of an acute course of uncomplicated gonorrhea: once 3 grams. Women need a repeated course in 2 weeks. Treatment of gynecologic diseases of infectious genesis, typhoid and paratyphoid: three times a day on 1500-2000 mg or 4 times a day on 1000-1500 mg. Treatment of a hay fever: 4 times a day on 500-750 mg, a course of 6-12 days. Therapy of a salmonellonositelstvo: three times a day on 1500-2000 mg, a course 2-4 weeks. At small operative measures for prevention of an endocarditis in 1 hour prior to manipulation appoint 3-4 grams of amoxicillin. Repeated reception in 9 hours is possible. To children the quantity of a medicine is reduced twice.

Special instructions:

At development of stability to amoxicillin the risk of superinfection increases. In such cases it is recommended to replace antibacterial drug. At patients from bacteremia endotoxic shock can develop. In certain cases cross allergic answers with cephalosporins at patients with hypersensitivity to penicillin are registered. At diarrhea it is not recommended to combine Ekobol's reception with antidiarrheal medicines which suppress an intestines peristaltics. After disappearance of the main symptoms of an infectious disease amoxicillin is recommended to be accepted within 3 more days. The price of Ekobol makes 50-100 rubles.

Medicinal interaction:

Ekobol's absorption decreases at reception of aminoglycosides, a glycosamine, antiacid medicines, purgatives. The converse effect is observed concerning ascorbic acid. The synergism is registered at treatment by bactericidal antibiotics (Vancomycinum, aminoglycosides, rifampicin, cephalosporins). A converse effect – at reception of bacteriostatic antibiotics (tetracycline, chloramphenicol, macroleads, streptocides, linkozamida). Ekobol reduces production of vitamin K, suppresses indestinal flora, strengthens effect of anticoagulants, reduces efficiency of the contraceptives containing estrogen. Concentration of amoxicillin increases due to decrease in canalicular secretion at reception of anti-inflammatory drugs of a nonsteroid origin, phenylbutazone, Allopyrinolum, duretichesky medicines, an oksifenbutazon and drugs which block secretion in tubules of kidneys. At treatment by Allopyrinolum skin rashes are registered. Ekobol increases absorbability of digoxin. Due to decrease in clearance toxic influence of a methotrexate amplifies.

Zdravzona

  • Ekobol of 500 mg No. 20 of a tabletkiavv Rus of joint stock company
  • Ekobol of 250 mg No. 20 of a tabletkiavv Rus of joint stock company
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Section: Antibiotics
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Education: Graduated from the Bashkir state medical university majoring in "Medical business". In 2011 gained the diploma and the certificate in Therapy. In 2012 received 2 certificate and the diploma in "Functional diagnosis" and "Cardiology". In 2013 completed courses on "Topical issues of otorhinolaryngology in therapy". In 2014 completed advanced training courses in "A clinical echocardiography" and courses in "Medical rehabilitation".

Experience: From 2011 to 2014 the Policlinic No. 33 Ufa worked as the therapist and the cardiologist in MBUZ. Since 2014 the Policlinic No. 33 Ufa works as the cardiologist and the doctor of functional diagnosis in MBUZ.

PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use Ekobol surely consult with the attending physician.