Флоксал Drug photo

The description is actual on 03.07.2014

  • Latin name: Floxal
  • ATH code: S01AE01
  • Active ingredient: Ofloxacin (Ofloxacin)
  • Producer: Dr. GERHARD MANN Chem. - Pharm. Fabrik, GmbH (Germany)


  • Floksal 0,3% contain eye drops in 1 ml of an ofloksatsin – 3 mg. Excipients: chloride benzalkoniya, acid solution hydrochloric, sodium chloride, sodium hydroxide solution, water.
  • The oculentum Floksal of 0,3% contains ofloxacin in number of 3 mg in 1 gram. Excipients: liquid paraffin; wool fat; white vaseline.

Release form

Drops for eyes represent transparent solution of pale yellow color. 5 ml of such solution in a polyethylene bottle with a cover dropper, one such bottle in a cardboard pack.

The oculentum is usually homogeneous, pale yellow color. 3 g of such ointment in a tuba, one such tuba in a cardboard pack.

Pharmacological action

Drug possesses antibacterial action.

Pharmacodynamics and pharmacokinetics


Ofloxacin is ftorkhinolony (to derivatives of hinolonovy acid), the antibacterial drug having bactericidal effect.

Range of antibacterial action of an ofloksatsin: facultative anaerobes, strict anaerobes, aerobes and some other bacteria, for example Chlamydia.

Frequency of occurrence of the acquired resistance of separate species of microorganisms varies depending on the region and changes eventually. Therefore the basic for purpose of the correct treatment of infections is the possession of information on local resistance. Cross resistance of an ofloksatsin and other ftorkhinolon is possible.

The most sensitive types:

  • gram-positive aerobic bacteria of Staphylococcus aureus, Bacillus spp.;
  • gram-negative aerobic bacteria of Acinetobacter lwoffi, Acinetobacter baumannii, Escherichia coli, Haemophilus influenzae, Klebsiella oxytoca, Enterobacter cloacae, Proteus mirabilis, Haemophilus parainfluenzae, Moraxella catarrhalis, Klebsiella pneumoniae, Serratia marcescens.

Types at which presence of the acquired resistance is possible:

  • gram-positive aerobic bacteria of Enterococcus faecalis, Corynebacterium spp., metsitilenrezistentny strains of Streptococcus pneumoniae, Staphylococcus aureus, Staphylococcus epidermidis;
  • gram-negative aerobic bacteria of Stenotrophomonas maltophilia, Pseudomonas aeruginosa.

The types possessing inborn resistance:

  • gram-positive aerobic bacteria of Enterococcus spp.


Efficiency of drug depends on a ratio of its greatest concentration in fabric and the minimum overwhelming concentration of the activator.

At repeated use medicine collects in a vitreous in medical concentration. After administration of drug of 5 times a day with exposure 5 minutes, in 1-2 hours concentration in intraocular liquid becomes the maximum, and 5-6 more hours it decreases to zero.

Floksal elimination half-life at its regular use makes from 3 to 7 hours of blood.

Indications to use

The infectious diseases of front department of an organ of sight caused by microorganisms sensitive to drug:

And also prevention and therapy of infectious complications after surgical interventions and injuries of an eye.


Side effects

The expressed reactions after regular use of an ofloksatsin develop seldom, the majority of them are reversible.

Directly after use of drug there can be a sight illegibility which disappears in several minutes.

  • From immunity: a conjunctiva hyperemia, a Quincke's edema, a burning sensation in an eye, anaphylactic reactions, stomatopharynx hypostasis.
  • From a nervous system: dizziness.
  • From an eye: a sensation of discomfort in eyes, irritation, a keratitis, a sight illegibility, conjunctivitis, photophobia, a xerophthalmus, dacryagogue.
  • From digestive organs: nausea.
  • From skin: face edemas and periorbital area.

There are data that at local use Stephens-Johnson's syndrome and a toxic epidermal necrosis very seldom developed. Relationship of cause and effect of such manifestations with ofloksotsiny is not established.

Application instruction of Floksal

Floksal the application instruction 3–4 times a day are offered to dig in eye drops on 1 drop for an eyelid of a sore eye.

The instruction of an oculentum Floksal also recommends to use drug konjyunktivalno. The ointment strip to 1,5 cm is put in a conjunctival sac by 2–3 times a day, at Chlamidia defeat — 5 times a day. Ointment and drops for eyes is not recommended to apply more than 2 weeks.

It is possible to combine an oculentum and drops Floksal. At joint local reception ointment the last needs to use more than one medicine.


Messages on cases of overdose were not. Therapy – symptomatic, it is necessary to wash out quickly an eye clear water.


Features of interaction are not studied.

Terms of sale

Medicine is sold only according to the recipe of the doctor.

Storage conditions

To protect from children. Drug needs to be stored the dark place at a temperature up to 25 °C. After opening of a tuba and or a bottle it is possible to use drug no more than 6 weeks.

Period of validity

3 years.

Special instructions

If there was an allergic reaction to Floksal, reception needs to be stopped.

Before the first administration of drug it is recommended to carry out microbiological crops of the material taken from a conjunctival sac for detection of sensitivity of bacteria to an ofloksatsin.

At long-term use development of bacterial resistance and emergence of microorganisms, insensitive to drug, is possible. If symptoms amplified or clinical improvement is absent it is necessary to stop treatment by Floksal and to begin alternative therapy.

During treatment it is forbidden to use rigid contact lenses. Therefore it is necessary to remove such lenses before use of drug and to dress them in 20 minutes after an instillation.

Floksal's analogs

Coincidence on the ATH code of the 4th level:

The following analogs of eye drops Floksal are known: Vigamoks, Unifloks.


  • Floksal of 0,3% of a drop eye 5 ml bottle dropper
  • Floksal of 0,3% oculentum of 3 g

Drugstore of IFC

  • Floksal of a hl drop. 0.3% of 5 ml, Dr. Gerhard Manngermaniya
  • Floksal hl ointment. 0.3% of 3 g, Dr. Gerhard Manngermaniya
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  • Floksal oculentum of 0.3% 3gdoktor Gerhard Mann (Germany)
  • Floksal eye drops of 0.3% 5mldoktor Gerhard Mann (Germany)


  • Floksal of 0,3% 3 g ointment glazn. Doctor Gerhard Mann (Germany)
  • Floksal of 0,3% 5 ml of a drop glazn. Doctor Gerhard Mann (Germany)
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Section: Antibiotics For eyes Antimicrobic
in more detail

Education: Graduated from the Vitebsk state medical university majoring in "Surgery". At university headed Council of students' scientific society. Professional development in 2010 - in "Oncology" and in 2011 - in "A mammology, visual forms of oncology".

Experience: Work in an all-medical network 3 years the surgeon (The Vitebsk hospital of an emergency medical service, Lioznensky TsRB) and in combination the regional oncologist and the traumatologist. Work farm the representative within a year in the Rubicon company.

Provided 3 improvement suggestions on the subject "Optimization of an Antibioticotherapia depending on Species Composition of Microflora", 2 works took prizes in a republican competition review of student's scientific works (1 and 3 categories).
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