Флуксен Drug photo

The description is actual on 21.07.2016

  • Latin name: Fluxen
  • ATH code: N06AB03
  • Active ingredient: Fluoxetine (Fluoxetine)
  • Producer: "ARTERIUM" of JSC Kiyevmedpreparat, Galichfarm (Ukraine)


Fluoxetine hydrochloride, microcrystallic cellulose, silicon dioxide anhydrous colloid, calcium stearate, gelatin, dye quinolinic yellow, titanium dioxide.

Release form

Gelatinous capsules of 20 mg of white color in the blister in a cardboard pack No. 10 or 30.

Pharmacological action


Pharmacodynamics and pharmacokinetics


Drug — antidepressant, selectively slows down the return serotonin reuptake, but practically does not influence capture of a dopamine and noradrenaline. Affects cholinergic H1 receptors poorly. Improves mood, lowers tension, sensation of fear, eliminates a dysphoria. Sedation is absent. Does not exert impact on function of cardiovascular system.


It is quickly soaked up from a gastrointestinal tract, at the same time, meal does not influence extent of absorption, but the speed of process is slowed down. Cmax in blood is reached in 6 hours. Communication with blood proteins at the level of 90%. Steady therapeutic action comes at Fluksen's reception within several weeks. Gets through GEB. It Biotransformirutsya in a liver to an active metabolite — a norfluoksetin. Drug with urine and a stake is removed.

Indications to use

Treatment of depressions of various genesis, obsessivno-compulsive states, alcoholism, bulimic neurosis (for weight reduction of a body and reduction of appetite).


High sensitivity to drug, children's age, a convulsive syndrome, diseases of kidneys, glaucoma, pregnancy and a lactation, epilepsy, prostate adenoma, a bladder atony.

Side effects

Headache, slackness, asthenic syndrome, dizziness, nervousness, fatigue, uneasiness, hyperkinesia, motive concern, frustration of a dream, convulsive states, extrapyramidal syndrome, dysarthtia, ataxy, paresthesia, neuropathy, neuralgia, neuritis, neurosis, decrease in concentration of attention, frustration of thinking, tremor, euphoria, hallucinations, paranoid reactions, suicide tendencies, psychosis, a stupor, changes on EEG, a coma.

Amblyopia, diplopia, glaucoma, mydriasis, iritis, sclerite, conjunctivitis, blepharitis, photophobia, disturbance of flavoring feelings, pain and sonitus, nose congestion, sinusitis, cough, thrombophlebitis, trombotsitemiya, lymphocytosis, nausea, vomiting, dryness in a mouth, increase in sialadens, gastritis, a lock, diarrhea, pancreatitis, a dysuria, cystitis, hypostases, dehydration, a meteorism, colitis, a furunculosis, an alopecia, local allergic reactions, perspiration, loss of body weight, a fever, fever, a hypothermia.

Fluksen, application instruction (Way and dosage)

The initial dose of Fluksen at a depression makes 20 mg/days. To take for 1 reception in the first half of day. In 4 weeks if necessary the dosage is increased by 20 mg a day. Duration of treatment is 2 — 3 months. The maximum daily dose of drug — 80 mg. For elderly patients the dose should not exceed 60 mg a day.

The medical effect is noted in 2-3 weeks. At bulimic neurosis a daily dose of Fluksen — 60 mg which is divided into 3 receptions.


It is shown by nausea, spasms, vomiting, dysfunction of cardiovascular and respiratory systems.


Drug is incompatible with MAO, furasolidone, Procarbazinum, other antidepressants, HP containing a St. John's Wort.

At a concomitant use of drug with the HP having high communication with proteins of plasma (anticoagulants peroral, cardiac glycosides, hypoglycemic means) increases risk of development of complications. It is incompatible with ethanol.

The risk of bleedings against a concomitant use with warfarin increases. Reception with drugs of lithium increases risk of development of toxic effects or decrease in concentration of lithium.

Terms of sale

Prescription issue.

Storage conditions

At a temperature up to 25 °C.

Period of validity

36 months.


Aleval, Reksetin, Arketis, Fluvoksin, Klofranil, Velafaks, Velaksin, Paksil.

About Fluksen

The majority of reviews of drug among the patients having a depression positive.

"… I take a pill Fluksen the second month, I drink on 20 in days. In a week my state considerably improved, but the dream still suffers. Appetite was gone completely in the beginning, and in a week everything was stabilized. Perhaps, the only serious minus — sexual desire decreased, there is no wish for sex absolutely".


  • Fluksen of a capsule 0.02g No. 30kiyevmedpreparat (Ukraine, Kiev)
  • Fluksen of a capsule 0.02g No. 10kiyevmedpreparat (Ukraine, Kiev)


  • Fluksen kaps. 0.02g No. 10kiyevmedpreparat
  • Fluksen kaps. 0.02g No. 10kiyevmedpreparat
Section: For a nervous system
in more detail

Education: Graduated from Sverdlovsk medical school (1968 - 1971) as "Paramedic". Graduated from the Donetsk medical institute (1975 - 1981) as "An epidemiologist, a hygienist". Passed postgraduate study in the Central scientific research institute of epidemiology Moscow (1986 - 1989). An academic degree – the candidate of medical sciences (degree is awarded in 1989, protection – the Central scientific research institute of epidemiology Moscow). Numerous advanced training courses are studied in epidemiology and infectious diseases.

Experience: Work as the manager of department of disinfection and sterilization of 1981 - 1992. Work as the manager of department of especially dangerous infections of 1992 - 2010. Teaching activity at Medical institute 2010 - 2013.

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