Форметин Drug photo

The description is actual on 03.06.2015

  • Latin name: Formetine
  • ATH code: A10BA02
  • Active ingredient: Metforminum (Metformin)
  • Producer: Pharmstandard-Leksredstva (Russia)


One tablet of Formetin depending on a dosage form may contain 500 or 850 mg., and also 1 g of a hydrochloride of Metforminum.

As a part of medicine there are also such auxiliary components as: magnesium stearate, middlemolecular povidone (polivinilpirollidon), and also sodium of a kroskarmelloz.

Release form

Formetin let out in the form of oval biconvex tablets of white color with applied on them on the one hand risky.

Tablets pack into planimetric blisters 10 pieces in everyone, and then place 3,6 or 10 blisters in cardboard packs.

Pharmacological action

Formetin treats group of guanyl guanidines, i.e. the hypoglycemic medical means intended for oral administration.

Pharmacodynamics and pharmacokinetics

Metforminum which is a part of medicine reduces liver gluconeogenesis speed, thus, considerably strengthening utilization of glucose and increasing at the same time sensitivity of body tissues to insulin.

Drug effectively works, without causing hypoglycemic reactions and without making impact on normal secretion of insulin pancreas cells.

At Formetin's reception the level of lipoproteins and triglycerides in blood decreases. Drug makes fibrinolitic impact as influences inhibitors of plasminogens activators of fabric type on a human body. Medicine contributes to normalization of body weight of patients with diabetes and is used for weight loss.

Active medicinal connection Metforminum is after taking the medicine absorbed in a stomach after a while and reaches the maximum concentration in blood in two and a half hours. Formetin is brought by kidneys.

Indications to use

Medical means is shown to patients with the excess weight and obesity at inefficiency of a dietotherapy suffering from a diabetes mellitus 2 types which is not characterized by tendency to ketoacidosis.

Formetin per se for weight loss is not appointed though at drug intake the weight of patients is really lost. Drug is effective in combination with an insulin therapy at a gross obesity which is characterized by secondary resistance to insulin.


It is not recommended to appoint drug to patients:

  • at dysfunction of kidneys and liver;
  • at diabetic ketoacidosis;
  • in a condition of a diabetic prekoma and a coma;
  • at infectious diseases in chronic or in an acute stage which can provoke dysfunction of kidneys (a hypoxia dehydration, sepsis, fever, infections of kidneys, shock) or lead to a hypoxia of fabrics (a myocardial infarction, respiratory, and also heart failure);
  • at an insulin therapy owing to the undergone surgeries or serious injuries;
  • at alcoholism in a chronic stage or after alcoholic poisoning;
  • at hypersensitivity;
  • during pregnancy and a lactation;
  • at acidosis;
  • at a hypocaloric diet.

Besides, you should not use Formetin in 2 days prior to X-ray and radio isotope inspections during which as a contrast agent use iodinated reagents.

Also it is not recommended to apply this medicine in treatment of patients is more senior than 60 years performing a hard physical activity in order to avoid development in them of lactic acidosis.

Side effects

At reception of medical means the following side effects can be shown: rash, metal smack in a mouth, nausea, diarrhea, vomiting and lack of appetite, an abdominal pain, the raised meteorism. Above-mentioned symptoms arise most often at the beginning of a therapeutic course of treatment and can be eliminated completely or facilitated at purpose of spasmolysants and antacids (atropinproizvodny drugs).

At prolonged treatment by Formetin at patients B12 hypovitaminosis, and also lactoacidosis, a hypoglycemia and anemia can develop.

Application instruction of Formetin (Way and dosage)

The dosage of medicine has to be established by the doctor in an individual order after a comprehensive assessment of a state of health of the patient and disease severity.

However in the application instruction of Formetin average initial daily therapeutic doses of drug – from 500 to 1000 mg/days are specified.

Correction of this dosage towards increase can be carried out after at most 15 days after an initiation of treatment at obligatory control of level of glucose to the patient's blood. The supporting drug dosage on average equals 1500-200 mg/days, but it should not exceed 3000 mg/days. For elderly patients the maximum daily dose should not be more than 1 g.

In order to avoid lactoacidosis for treatment of patients with disturbances of a metabolism it is recommended to use the underestimated dosages.

Formetin's pill is taken after food, the daily medicinal dose can be divided into 2 inclusion in avoidance of emergence of side effects from the alimentary system.


In case of overdose by drug at the patient lactoacidosis which without appropriate treatment can lead to a fatal outcome can develop.


Formetin is not recommended to accept together with:

  • Danazol, to exclude strengthening of hyper glycemic influence of the last;
  • Chlorpromazinum to avoid a glycemia;
  • Akarbaza, inhibitors of monoaminoxidase and an angiotensin-converting enzyme, derivatives of a sulfonilmochevina and Clofibratum, anti-inflammatory nonsteroid drugs, Oxytetracyclinum and β-adrenoblockers in order to avoid strengthening of properties of Metforminum which is Formetin's part;
  • Cimetidinum which slows down process of a conclusion of Metforminum organism;
  • the oral contraceptives, glucagon, thiazide diuretics, hormones of a thyroid gland derivative of niacin and a fenotiazin to prevent decrease in efficiency of a metfomin;
  • derivatives of coumarin (anticoagulants) as Metforminum weakens their action.

Besides, it is forbidden to accept medical means and to take alcohol since it significantly increases probability of development of lactoacidosis.

Correction of dosages of Formetin is required after or during treatment of the patient by means of neuroleptics.

Terms of sale

From drugstores Formetin release according to the recipe of the doctor.

Storage conditions

Medical means needs to be stored surely in the dry place at 15-25 C, far from children and light.

Period of validity

2 years.

Special instructions

At Formetin's reception it is necessary to exercise control of functions of kidneys of the patient, and also to carry out the analysis on identification of level of creatine and glucose to blood. During use of drug it is forbidden to take alcohol or to accept the drugs containing ethanol.

Formetin in itself does not influence ability to driving of the car or to work with potentially dangerous units and mechanisms.

However at joint administration of drug with insulin or derivatives of a sulfonilmochevina (i.e. hypoglycemic drugs) it is worth refusing implementation of the types of activity demanding the increased concentration of attention.


Coincidence on the ATH code of the 4th level:

Bagomet, Gliminfor, Glyukofazh, Glikon, Gliformin, Lanzherin, Metospanin, Metfogamma, Metadiyen, Metforminum, Nova Mat, Siofor, Novoformin, Sofamet, Metforminum Hydrochloride, Forminum Pliva.


  • Formetin of 1 g No. 60 of a tabletkifarmstandart-Leksredstvo of joint stock company
  • Formetin of 1 g No. 30 of a tabletkifarmstandart-Leksredstvo of joint stock company
  • Formetin of 500 mg No. 30 of a tabletkifarmstandart-Leksredstvo of joint stock company
  • Formetin of 500 mg No. 60 of a tabletkifarmstandart-Leksredstvo of joint stock company
  • Formetin of 850 mg No. 60 of a tabletkifarmstandart-Leksredstvo of joint stock company
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Section: Diabetic
PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use Formetin surely consult with the attending physician.