Ftalazolum

Фталазол Drug photo

The description is actual on 19.06.2014

  • Latin name: Phthalazolum
  • ATH code: A07AB02
  • Active ingredient: Phthalylsulfathiazole (Phthalylsulfathiazole)
  • Producer: Irbitsky HFZ, Russia; Pharmstandard-leksredstva, Russia; Dalkhimfarm, Russia; Biosynthesis, Russia; Biochemist, Russia; STALEMATE Kiyevmedpreparat, Ukraine.

Structure

The tablet of drug contains phthalylsulfathiazole – 0,5 g and excipients (talc, potato starch, calcium stearate).

Release form

White or yellowish flat tablets, facet, risk, packaging on 10, 20, 30, 50, 1000, 1500, 2000, 5000 or 10000 pieces.

Pharmacological action

Antibacterial, antiinflammatory, group of streptocides.

Pharmacodynamics and pharmacokinetics

Antibacterial activity of active ingredient, as well as all other streptocides, is connected with the fact that the structure of drug is similar from the para-aminobenzoic acid which is directly involved in synthesis of folic acid in a cell of a microbe. And development and growth of harmful microorganisms, directly depends on processes of synthesis of the purine and pirimidinovy bases, by means of folic acid. Use enough high doses of phthalylsulfathiazole allows to eliminate microbes, despite PABK stocks in fabrics, does not allow to be formed to new more resistant strains of microorganisms.

Also drug possesses antiinflammatory action. It stimulates processes of development of glucocorticosteroids, reduces intensity of migration of leukocytes.

Medicine shows the greatest activity in relation to Pneumococcus, Meningococcus, Shigella dysenteriae, Streptococcus, Gonococcus, Staphylococcus, Pseudomonas aeruginosa, Proteus vulgaris, Escherichia coli.

After reception of means its greatest concentration concentrates in a rectum (most of all in an intestines gleam).

Indications to use of Ftalazolum

From what Ftalazolum helps?

From what appoint the tablets Ftalazolum?

States after intestines operations can be the indication to use of Ftalazolum.

Contraindications

Side effects

  • developing of an allergy is possible;
  • headache;
  • anemia at long reception;
  • stomatitis, gastritis, nausea, pains in epigastric area;
  • formation of stones in kidneys.

Application instruction of Ftalazolum (Way and dosage)

The specialist, depending on degree of sensitivity of intestinal microflora to streptocides has to appoint a dosage and duration of treatment.

According to the instruction on Ftalazolum, the daily dose should not exceed 7 grams, one-time – 2 grams.

At the acute course of a disease appoint:

  • 1-2 day – 2 tablets, each 4 hours;
  • 3-4 day – 2 tablets, each 6 hours;
  • 5-6 day – 2 tablets – each 8 hours.

Further treatment:

  • 1-2 day – 2 tablets in 4 hours, at night – one (in the sum — 10);
  • 3-4 day – 8 tablets a day, with an interval at 4 o'clock, except night time;
  • 5 day – 6 tablets, in 4 hours everyone.

How to accept Ftalazolum to children?

Decrease in a daily dose to 0,2 g on weight kg (children till 3 years), to 0,4 - 0,8 g on weight kg is made for children (6 years are more senior). Administration of drug is distributed on equal parts, the sleep pattern is not broken. The course of treatment, as a rule, makes one week.

Overdose

Emergence of a macrocytosis and pancytopenia, strengthening of side effects is possible. It does not occur if in parallel with drug intake, appoint folic acid.

Treatment is made according to the shown symptoms.

Interaction

Not to combine with acids, Hexamethylenetetramine, adrenaline and kislotoreagiruyushchy means.

At a concomitant use of Ftalazolum with Oxacillinum, efficiency of the last decreases.

At a combination to levomycetinum, nitrofuran and thioacetazone the risk of emergence of side effects increases.

Barbiturates and p-aminosalicylic acid, antibiotics and other streptocides strengthen impact of drug on harmful microorganisms.

The combination to anticoagulants of indirect action increases activity of the last.

Terms of sale

The recipe is required.

Storage conditions

In unavailable to children, dark, cool place.

Period of validity

4 years.

At pregnancy and a lactation

Medicine well and quickly breaks a gematoplatsentarny barrier, it is found in breast milk and extremely adversely influences health of the child or a fruit. Therefore drug at pregnancy and feeding a breast is not appointed.

About Ftalazolum

About drug use good. Medicine quickly copes with diarrhea, well. From advantages note the low cost and safety of means, it can be given to children. Ftalazolum is in any first-aid kit and is very often applied as means of the emergency help.

Zdravzona

  • Ftalazolum of 500 mg No. 10 tabletkibiosintez joint stock company
  • Ftalazolum of 500 mg No. 10 of joint stock company tablet/Dalkhimfarm/Dalkhimfarm

Drugstore of IFC

  • Ftalazolum tbl 500 mg No. 10, Biosynthesis (Penza) Russia
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Apteka24

  • Ftalazolkiyevmedpreparat (Ukraine, Kiev)
  • Ftalazoldarnitsa (Ukraine, Kiev)
  • Ftalazollubnyfarm (Ukraine, Lubna)
  • Ftalazolzdorovye (Ukraine, Kharkiv)
  • Ftalazolkrasny star (Ukraine, Kharkiv)

Paniapteka

  • Tab. Ftalazolum 0.5g No. 10 Health
  • Tab. Ftalazolum 0.5g No. 10 Health
  • Tab. Ftalazolum 0.5g No. 10 Health
  • Tab. Ftalazolum 0.5g No. 10 Health
  • Tab. Ftalazolum 0.5g No. 10 Health

BIOSPHERE

  • Ftalazolum of 0,5 g No. 10 of the tab. Irbitsky himfarmzavod (Russia)
  • Ftalazolum of 500 mg No. 10 of the tab. of Darnits (Ukraine)
  • Ftalazol-KMP 500 mg No. 10 of the tab. Kiyevmedpreparat of joint stock company (Ukraine)
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Section: Gastrointestinal
PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use Ftalazolum surely consult with the attending physician.