Fucidinum

Фуцидин Drug photo

The description is actual on 23.04.2016

  • Latin name: Fucidin
  • ATH code: D06AX01
  • Active ingredient: Fuzidovy acid (Fusidic acid)
  • Producer: Leo Laboratories Limited (Ireland)

Structure

  • Cream Fucidinum in number of 1 grams includes 20 mg of fuzidovy acid. Additional substances: glitserol 85%, cetyl alcohol, water, liquid paraffin, polysorbate, soft white paraffin, potassium sorbate, Acidum hydrochloricum, butylhydroxyanisole.
  • Ointment Fucidinum in number of 1 grams includes 20 mg of fuzidovy acid. Additional substances: liquid paraffin, white soft paraffin, lanolin, cetyl alcohol.

Release form

  • White homogeneous cream. 15 grams of cream in a metal tuba, 1 tuba in a paper pack.
  • Light yellow translucent homogeneous ointment. 15 grams of cream in a metal tuba, 1 tuba in a paper pack.

Pharmacological action

Local antibacterial action.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

Antibacterial agent of bacteriostatic action. Treats Fusidinums, antimicrobic substances which effect is based on disturbance of biosynthesis of protein in a cell of a bacterium.

Gram-positive microorganisms and gram-negative cocci are most sensitive to the drug Fucidinum (Fucidin): Streptococcus pyogenes, Neisseria meningitidis and gonorrhoeae, Staphylococcus aureus and epidemridis, Corynebacterium minutissimum, Nocardia asteroides, and also representatives of the sorts Pseudomonas and Clostridium.

Drug is not active concerning colibacillus, and also representatives of the sorts Salmonella and Proteus, protozoa and mushrooms.

Pharmacokinetics

At outside use absorption in a system blood stream low.

Indications to use

The skin infections provoked by the microorganisms sensitive on the relations to fuzidovy acid.

Contraindications

Ointment Fucidinum (Fucidin and Fucidin krem) is taken during pregnancy and a lactation with caution.

Side effects

These phenomena are observed seldom and are expected approximately at 5% of patients.

  • Reactions from an eye: irritation of a conjunctiva.
  • Allergic phenomena: Quincke's edema, urticaria, eczema.
  • Dermatological phenomena: periorbital hypostasis, irritation of skin, eczema, rash and itch of skin, xeroderma, contact dermatitis, erythema.

Application instruction of Fucidinum (Way and dosage)

Cream and ointment are applied and used only outwardly.

Cream Fucidinum, application instruction

To patients of all age appoint to apply cream Fucidinum on the struck areas of skin to 4 times a day. At use of bandages from a gauze the frequency of drawings is lowered to 2 times a day.

Treatment duration cream depends on clinic and a form of a disease and averages 1-2 weeks.

Ointment Fucidinum, application instruction

To patients of all age appoint to apply ointment Fucidinum on the struck areas of skin to 4 times a day. At use of bandages from a gauze the frequency of drawings is lowered to 2 times a day.

Treatment duration ointment depends on clinic and a form of a disease and averages 1-2 weeks.

Overdose

There are no data on the registered overdose cases.

Interaction

Interaction with other medicines was not investigated.

Terms of sale

It is possible to get only according to the recipe.

Storage conditions

Drug needs to be protected from children. Cream is stored at a temperature up to 25 °C. Ointment is stored at a temperature up to 30 °C.

Period of validity

Three years.

Special instructions

It is impossible to apply drug on skin a century as fuzidovy acid causes irritation of fabrics of a conjunctiva.

Cream includes in the structure butylhydroxyanisole, sorbate of potassium and cetyl alcohol, and ointment – cetyl alcohol and lanolin. These substances are the reason of development of the local allergic skin phenomena.

Butilgidroksianizol can also serve as the reason of irritation mucous and an eye.

When using fuzidovy acid development of bacterial resistance is not excluded. The long or regularly repeating use is capable to increase risk of emergence of stability to antibacterial agents.

Influence of medicine on ability to driving is not revealed.

Analogs

Coincidence on the ATH code of the 4th level:

The most widespread analogs of drug are listed below: Fusidinum, Fuziderm, Fusidinum sodium, Futsitalmik.

Zdravzona

  • Fucidinum of 2% 15 g ointment
  • Fucidinum of 2% 15 g cream
  • Fucidinum of of 15 g cream

Drugstore of IFC

  • Fucidinum ointment of 2% 15 g, Leo Pharmaceutical Productsdaniya
  • Fucidinum of cream 15 of, Leo Pharmaceutical Productsdaniya
  • Fucidinum cream of 2% 15 g, Leo Pharmaceutical Productsdaniya
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Section: Antibiotics Dermatological
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Education: Graduated from the Vitebsk state medical university majoring in "Surgery". At university headed Council of students' scientific society. Professional development in 2010 - in "Oncology" and in 2011 - in "A mammology, visual forms of oncology".

Experience: Work in an all-medical network 3 years the surgeon (The Vitebsk hospital of an emergency medical service, Lioznensky TsRB) and in combination the regional oncologist and the traumatologist. Work farm the representative within a year in the Rubicon company.

Provided 3 improvement suggestions on the subject "Optimization of an Antibioticotherapia depending on Species Composition of Microflora", 2 works took prizes in a republican competition review of student's scientific works (1 and 3 categories).
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