Гексаметилентетрамин Drug photo

The description is actual on 07.09.2015

  • Latin name: Hexamethylentetraminum
  • ATH code: J01XX05
  • Active ingredient: Methenamin
  • Producer: JSC NOVOSIBKHIMFARM, Tatkhimfarmpreparata (Russia)



Release form

  • Solution for in/in introductions (40%) in glass ampoules on 5 ml in cardboard packaging.
  • Mg tablets 250, 500 in a glass flask No. 10.

Pharmacological action

Bactericidal, fungicidal, virulitsidny.

Pharmacodynamics and pharmacokinetics


The antiseptic effect of drug is based on its property to emit formaldehyde which influences proteinaceous structures of microorganisms in acid medium, destroying them.


Completely and quickly it is also soaked up in a gastrointestinal tract. Practically does not contact proteins of plasma. Bioavailability — 30-60%. An elimination half-life — 4,3 hours. It is removed by kidneys within a day.

Indications to use


Hypersensitivity to drug, hepatonephric insufficiency, organism dehydration, pregnancy and the period of a lactation, age till 6 flyings.

Side effects

Nausea, pains in epigastric area, diarrhea, vomiting; defeat of a parenchyma of kidneys, hamaturia, crystalluria, albuminemia; allergic local reactions: reddening, skin rashes, morbidity and an itch in an injection site.

Hexamethylenetetramine, application instruction

The adult — hexamethylenetetramine solution (40%) intravenously 5-10 ml; in tablets 3-4 times a day on 0,5-1 g on reception, to children of 0,1-0,5 g.


Perhaps in rare instances emergence of dysuric frustration and allergic reactions, and also, hamaturia, irritation of urinary tract.


Drug in solutions is incompatible with alkaloid salts, acids, Pyramidon, tannins, caffeine, salicylates, salts of heavy metals, Resorcin, glucose, Salol. Loses activity at simultaneous use with streptocides.

Efficiency of Hexamethylenetetramine decreases at its joint appointment with the HP capable to alkalize urine (antiacid drugs, karboangidraza inhibitors, thiazide diuretics, hydrosodium carbonate).

Terms of sale

According to the recipe.

Storage conditions

In the dry place in tight packaging at a temperature not above 20 °C.

Period of validity

Hexamethylenetetramine ampoules — 5 years, tablets — 10 years.


Analogs of Hexamethylenetetramine on the ATH code are Hexamin, Methenamin, Amiinoform, Metraminum, Urotropin, Cystogenum, Urisolum, Cystaminum, Formaminum.

Analogs on clinical action — Galenofillipt, 5-HOK, Diksin, Zivoks, Kirin, the Dioxidin, Kubitsin, Nitroxoline, Monural, Ristomycinum sulfate, Urofosfabol, Sangviritrin, the Eucalyptus tincture, Fosfomitsin, Zeniks, Linezolid-Teva, Amizolid.

About Hexamethylenetetramine

Responses are practically absent as in connection with emergence of more effective remedies, Hexamethylenetetramine has no broad use.

Section: Antifungal Antimicrobic
in more detail

Education: Graduated from Sverdlovsk medical school (1968 - 1971) as "Paramedic". Graduated from the Donetsk medical institute (1975 - 1981) as "An epidemiologist, a hygienist". Passed postgraduate study in the Central scientific research institute of epidemiology Moscow (1986 - 1989). An academic degree – the candidate of medical sciences (degree is awarded in 1989, protection – the Central scientific research institute of epidemiology Moscow). Numerous advanced training courses are studied in epidemiology and infectious diseases.

Experience: Work as the manager of department of disinfection and sterilization of 1981 - 1992. Work as the manager of department of especially dangerous infections of 1992 - 2010. Teaching activity at Medical institute 2010 - 2013.

PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use Hexamethylenetetramine surely consult with the attending physician.