And whether you know...
- Solution for in/in introductions (40%) in glass ampoules on 5 ml in cardboard packaging.
- Mg tablets 250, 500 in a glass flask No. 10.
Bactericidal, fungicidal, virulitsidny.
Pharmacodynamics and pharmacokinetics
The antiseptic effect of drug is based on its property to emit formaldehyde which influences proteinaceous structures of microorganisms in acid medium, destroying them.
Completely and quickly it is also soaked up in a gastrointestinal tract. Practically does not contact proteins of plasma. Bioavailability — 30-60%. An elimination half-life — 4,3 hours. It is removed by kidneys within a day.
Indications to use
- Infectious diseases of urinary tract.
- Keratitis, iridocyclites.
- Cholangites and cholecystitises.
- Allergic skin diseases.
- Meningitis, arachnoiditis, encephalitis.
Hypersensitivity to drug, hepatonephric insufficiency, organism dehydration, pregnancy and the period of a lactation, age till 6 flyings.
Nausea, pains in epigastric area, diarrhea, vomiting; defeat of a parenchyma of kidneys, hamaturia, crystalluria, albuminemia; allergic local reactions: reddening, skin rashes, morbidity and an itch in an injection site.
Hexamethylenetetramine, application instruction
The adult — hexamethylenetetramine solution (40%) intravenously 5-10 ml; in tablets 3-4 times a day on 0,5-1 g on reception, to children of 0,1-0,5 g.
Perhaps in rare instances emergence of dysuric frustration and allergic reactions, and also, hamaturia, irritation of urinary tract.
Drug in solutions is incompatible with alkaloid salts, acids, Pyramidon, tannins, caffeine, salicylates, salts of heavy metals, Resorcin, glucose, Salol. Loses activity at simultaneous use with streptocides.
Efficiency of Hexamethylenetetramine decreases at its joint appointment with the HP capable to alkalize urine (antiacid drugs, karboangidraza inhibitors, thiazide diuretics, hydrosodium carbonate).
Terms of sale
According to the recipe.
In the dry place in tight packaging at a temperature not above 20 °C.
Period of validity
Hexamethylenetetramine ampoules — 5 years, tablets — 10 years.
Coincidence on the ATH code of the 4th level:
- Bacteriophage Klebsiyell Pnevmonii
- Bacteriophage Proteyny
- Kolya's bacteriophage
- Bacteriophage Dysenteric
- Bacteriophage Salmonellezny
- Bacteriophage Pyocyanic
- Bacteriophage Koliproteyny
- Bacteriophage Streptococcal
- Bacteriophage Klebsiyell Polivalentny Cleared
- Bacteriophage Staphylococcal
Analogs of Hexamethylenetetramine on the ATH code are Hexamin, Methenamin, Amiinoform, Metraminum, Urotropin, Cystogenum, Urisolum, Cystaminum, Formaminum.
Analogs on clinical action — Galenofillipt, 5-HOK, Diksin, Zivoks, Kirin, the Dioxidin, Kubitsin, Nitroxoline, Monural, Ristomycinum sulfate, Urofosfabol, Sangviritrin, the Eucalyptus tincture, Fosfomitsin, Zeniks, Linezolid-Teva, Amizolid.
Responses are practically absent as in connection with emergence of more effective remedies, Hexamethylenetetramine has no broad use.
Section: Antifungal Antimicrobic
PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use Hexamethylenetetramine surely consult with the attending physician.