Yohimbine hydrochloride

Гидрохлорид Йохимбина Drug photo

The description is actual on 29.12.2014

  • Latin name: Yohimbin hydrochloride
  • ATH code: G04BE04
  • Active ingredient: Yohimbine (Yohimbine)


One tablet of Yohimbine of a hydrochloride contains 5 mg of the active ingredient of the same name.
Excipients: monohydrate of lactose, starch, gipromelloza, calcium stearate, tselaktoza.

Release form

Yohimbine a hydrochloride – tablets of white or pale yellow color. Drug is issued on 50 tablets in a plastic can or the polymeric container; one such can or the container in a pack from paper.

Pharmacological action

Stimulates a potentiality.

Pharmacodynamics and pharmacokinetics


Yohimbine the hydrochloride strengthens a potentiality (aphrodisiac) and is the alkaloid received from Corynanthe tree bark.
Action is caused by selective suppression α2-адренорецепторов. Activates adrenergic neurons in a head brain, has psychogogic effect. It is probable that it also influences dopaminergic, serotonergic and cholinergic systems.

Yohimbine the hydrochloride stimulates a sexual behavior and recovers the sexual activity lowered because of a stress and the broken erection.

The medical effect is explained by the effects of Yohimbine of a hydrochloride influencing a nervous system. Perhaps strengthens blood circulation of a penis and has direct effect on the fabrics participating in an erection.


It is completely soaked up in intestines within an hour. The greatest concentration in blood comes in 40-70 minutes. At oral administration in the recommended doses of accumulation of drug in an organism does not occur. The elimination half-life depends on the accepted dose.

82% of Yohimbine of a hydrochloride contact plasma proteins. It is metabolized in a liver. Two main metabolites are known: active 11 hydroxyyohimbine and slaboaktivny 10 hydroxyyohimbine.

Indications to use

Therapy of functional and psychogenic impotence, man's climax, bladder atony.


  • Hypersensitivity to Yohimbine to a hydrochloride or other components of drug.
  • The expressed arterial hypotension.
  • Severe damages of a liver and kidneys.
  • Therapy of an adrenomimetikama.
  • This medicine is not intended for use by women and children.

Side effects

Application instruction (Way and dosage)

The instruction orders to accept drug orally during food, washing down with water and not chewing. On 1-2 tablets from one to three times a day.

The dose is recommended to be selected individually. An initial dose – 2,5 mg 3 times a day, maximum – 1-2 tablets three times a day.
The effect in some cases comes in several weeks. Duration of therapy depends on clinic of a disease and can make 4 weeks.


Overdose symptoms. In 30-45 minutes after reception of an overdose generalized paresthesias, weakness, memory disturbances, dizziness, a headache, a tremor, increase of pressure, tachycardia, sensation of fear, increase in level of noradrenaline in blood, nausea, a mydriasis, vomiting, perspiration develop. These symptoms can will remain within 2-3 hours.

Treatment: to stop administration of drug, to make a gastric lavage, then to accept absorbent carbon. As the antidote can be used the Clonidine which levels mental effects and frustration of a sympathetic nervous system.

For therapy of hypertensive crisis β-adrenoblockers in combination with α-adrenoblockers or peripheral vazodilatator are recommended. At overdose it is forbidden to use neuroleptics fenotiazinovy a row.


At joint reception with a clonidine effects of drugs vzaimoneytralizutsya.

Klopiramin increases concentration of Yohimbine of a hydrochloride in a blood plasma.

Yohimbine the hydrochloride strengthens effect of antidepressants and increases risk of development, the side effects caused by them.

Joint reception with tranquilizers weakens activity of the last.

Terms of sale

Drug can be bought only according to the recipe.

Storage conditions

  • To store at a temperature not higher than 25 degrees.
  • To protect from children.

Period of validity

Three years.

Special instructions

The composition of drug includes lactose and to patients with intolerance of a galactose, a syndrome of glyukozo-galaktozny malabsorption or insufficiency of lactase it is forbidden to apply this means.


The closest analogs on structure: Yohimbine "Spiegel", Yokhimbe evalar, Yohimbine Forte, Super Yokhimbe Plus.

Section: For increase of a potentiality Urological
in more detail

Education: Graduated from the Vitebsk state medical university majoring in "Surgery". At university headed Council of students' scientific society. Professional development in 2010 - in "Oncology" and in 2011 - in "A mammology, visual forms of oncology".

Experience: Work in an all-medical network 3 years the surgeon (The Vitebsk hospital of an emergency medical service, Lioznensky TsRB) and in combination the regional oncologist and the traumatologist. Work farm the representative within a year in the Rubicon company.

Provided 3 improvement suggestions on the subject "Optimization of an Antibioticotherapia depending on Species Composition of Microflora", 2 works took prizes in a republican competition review of student's scientific works (1 and 3 categories).
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