Hyoxysonum

Гиоксизон Drug photo

The description is actual on 20.10.2014

  • Latin name: Hyoxysonum
  • ATH code: D07CA01
  • Active ingredient: Hydrocortisone (Hydrocortisone) + Oxytetracyclinum (Oxytetracycline)
  • Producer: NIZHPHARM, Quinacrine, Pharmaceutical factory of St. Petersburg, Murom instrument-making plant (Russia)

Structure

As a part of ointment 3 g of a hydrochloride of Oxytetracyclinum (activity of 860 PIECES/mg), 1 g of acetate of a hydrocortisone contain.

Also ointment contains excipients: a liquid paraffin, nipagin, to 100 g of medical vaseline.

Release form

Ointment is issued in aluminum tubas on 25 or 10 g. Tubas together with the application instruction of drug are packed into a cardboard pack.

Pharmacological action

Drug has antibacterial and local antiinflammatory effect.

Indications to use

Drug is shown to use at:

  • furunculosis;
  • the infected intertrigo;
  • anthrax;
  • dermatitis of newborns (exfoliative and violent);
  • folliculites;
  • impetigo;
  • contaminated wounds and eczemas;
  • to the small tortoiseshell of the newborn;
  • erysipelatous inflammation;
  • erosion;
  • seborrheas;
  • to multiformny exudative erythema;
  • allergic and simple dermatitis;
  • stings of insects;
  • burns;
  • purulent and allergic diseases of outside acoustical pass;
  • "solar" erythematic rashes;
  • varicose ulcers of a shin;
  • freezing injuries.

Pharmacodynamics and pharmacokinetics

Hyoxysonum is the combined drug oppressing developments of the inflammatory reactions on skin and which especially have an allergic origin which are complicated by a bacterial infection. The effect is reached thanks to total action of the components which are a part of Hyoxysonum.

Substance Oxytetracyclinum, being an antibiotic of tetracycline group, possesses bacteriostatic action. Proves to be actively concerning gram-negative and gram-positive bacteria, Mycoplasma spp., Rickettsia spp., Chlamydia spp., Treponema spp.

The glucocorticosteroid a hydrocortisone renders antiallergic, antipruritic, anti-exudative and antiinflammatory effects. Oppressing activity of a phospholipase of A2, substance reduces education from phospholipids of cellular covers of arachidonic acid. Release of interleykin, and also other cytokines which possess antiinflammatory action is oppressed, and also local allergic reactions and release of a histamine are slowed down. Adjournment of collagen in skin and protein synthesis decreases, also the hydrocortisone weakens proliferative processes and serves as an obstacle for development of connecting fabric.

Contraindications

Drug is contraindicated to use at:

  • existence of hypersensitivity to one or several components which are a part of drug;
  • skin tumors;
  • mycosis;
  • tuberculosis cutis;
  • precancerous states;
  • viral diseases of skin (chicken pox, herpes);
  • pregnancies;
  • the lactation period (in case of use on the extensive centers of defeat).

Side effects

Side effects at use of the drug Hyoxysonum can be shown in irritations of skin, rash, an itch, emergence of allergic reactions and superinfection is also possible.

In case of use of ointment on face skin can act as side effects an atrophy of the hypodermic cellulose which is in area of a mouth, and also a teleangiectasia.

System side effects of glucocorticoid means putting ointment on big surfaces, and also prolonged use of ointment can cause Hyoxysonum.

Ointment Hyoxysonum, application instruction (Way and dosage)

It is applied outwardly, put locally.

0,5-1 g of ointment are applied directly on affected areas with a thin layer from 1 to 3 times a day. It is also possible to apply ointment on a sterile gauze then it should be put to skin and to record bandage. Treatment duration by means of the drug Hyoxysonum is selected individually, based on localization and extent of defeat. But at the same time the maximum duration of treatment – two weeks.

In case of use of drug on face skin, Hyoxysonum is pointwise applied on affected areas with a thin layer. A course of treatment – no more than 7-10 days.

Overdose

Data on overdose by the drug Hyoxysonum are absent.

Interaction

Data on medicinal interaction of Hyoxysonum with other drugs are absent.

Terms of sale

Drug is released in drugstores according to the recipe.

Storage conditions

Drug should be stored in the place unavailable to children. The maximum temperature of storage — 20 °C.

Period of validity

3 years.

Special instructions

At treatment of GKS vaccination against smallpox, and also other types of immunization is not recommended that is connected with immunodepressive effect of glucocorticosteroids.

In case of use of ointment on face skin, duration of treatment has to be short. It is connected with the increased absorbability of drug on these sites that can serve as an origin of side effects.

Analogs

Coincidence on the ATH code of the 4th level:

Akriderm, Triderm, Oxycortum.

Zdravzona

  • Hyoxysonum of 10 g mazyakrikhin HFK of joint stock company
  • Hyoxysonum ointment 10gnizhfarm of joint stock company

Drugstore of IFC

  • Hyoxysonum ointment 10 of, Murom priborostroit.z-d (Murom) Russia
  • Hyoxysonum ointment 10 of, Nizhpharm (N. Novgorod) Russia
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Apteka24

  • Gioksizonnizhfarm (Russia, Nizhny Novgorod)

Paniapteka

  • Ointment Hyoxysonum of 10 g

BIOSPHERE

  • Hyoxysonum of 10 g ointment in tubenizhfarm (Russia)
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Section: Antibiotics
PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use Hyoxysonum surely consult with the attending physician.