Глаупрост Drug photo

The description is actual on 12.07.2016

  • Latin name: Glauprost
  • ATH code: S01EE01
  • Active ingredient: Latanoprost (Latanoprost)
  • Producer: C.O. Rompharm Company S.R.L. (Romania)


In 1 ml of drops of 50 mkg of a latanoprost.

Release form

Drops in a bottle on 2,5 ml and 5 ml.

Pharmacological action

Reduces intraocular pressure.

Pharmacodynamics and pharmacokinetics


Protivoglaukomny drug, synthetic analog of F2α prostaglandin.  On the one hand, it expands eye vessels, activates outflow of watery moisture and improves microcirculation that normalizes intraocular pressure. On the other hand — regulates a cellular metabolism, improves a trophicity of fabrics, increasing the maintenance of tsAMF. It allows to apply it at an open angle glaucoma as monotherapy drug.

Decrease in intraocular pressure is noted in 3-4 h, and the systemic effect proceeds 24 h.


Gets through a cornea, it is hydrolyzed to an active form. Cmax in watery moisture is reached in 2 h after an instillation. The metabolism occurs in a liver, in eye tissues is almost not metabolized. Metabolites possess weak activity. It is removed by kidneys. An elimination half-life — 17 min.

Indications to use

  • Increase of VGD (intraocular pressure);
  • open angle glaucoma.



With care it is appointed at an aphakia, a pseudo-aphakia with a rupture of a capsule of a crystalline lens, existence of risk of macular hypostasis, inborn glaucoma (there is no experience of use).

Side effects

  • Eye pain;
  • burning sensation in eyes;
  • sight misting;
  • feeling of sand in eyes;
  • itch;
  • the century swelled;
  • blepharitis;
  • lengthening of eyelashes and strengthening of their pigmentation;
  • conjunctiva hyperemia;
  • change of pigmentation of an iris;
  • darkening of skin century;
  • asthma;
  • dizziness;
  • attacks of bronchial asthma;
  • muscle and joints pains.

Glauprost, application instruction (Way and dosage)

Dig in in eyes on 1 drop of 1 times in the evening. If procedure is missed, then the following dose is entered in due time next day, without doubling it.

Use of drug causes discoloration of eyes in connection with increase in a brown pigment. It is noted usually at persons with the mixed coloring of an iris. At intensive change of pigmentation treatment is stopped. At patients who apply drops in one eye emergence of a heterochromia is possible. The doctor informs the patient on probability of discoloration of eyes. Changes of eyelashes in the form of lengthening and a thickening take place after the end of treatment.

If other eye drops them are appointed it is necessary to enter with an interval 5 min. Before procedure contact lenses take out and insert in 15 min.


Overdose is shown by symptoms: hyperemia, irritation mucous eyes. Symptomatic therapy is carried out.


Simultaneous use of other analogs of prostaglandins causes paradoxical increase of pressure in an eye. Pharmaceutical it is incompatible with tiomersaly (there is precipitation). At use with Timololum, Pilocarpinum, adrenomimetika the additive action concerning intraocular pressure is noted.

Terms of sale

According to the recipe.

Storage conditions

Temperature is from 2 ° to 8 °C. To store an open bottle at the room temperature and to use within a month.

Period of validity

2 years.

Glauprost's analogs

Coincidence on the ATH code of the 4th level:

Glaumaks, Ksalatan, Latanoks, Prolatan, Lanotan.

About Glauprosta

By results of researches, eye drops of Glauprost at patients with the level of the intraocular pressure of 24-25 mm of mercury. lowered it by 6-8 mm of mercury. If to compare its efficiency to Timololum solution, then one instillation of Glauprost is equivalent to 2-fold use in day of Timololum. This drug renders longer and expressed hypotensive effect what also responses of patients testify to.

  • "… Glauprost arranges with the fact that it is possible to drip only once a day. I transfer treatment well, there is no irritation of eyes".
  • "… These drops are used by the husband, help well, but in half a year noticed discoloration of eyes. The doctor did not warn us therefore we began to panic".
  • "… Help well, but are expensive if to consider that treatment of glaucoma lifelong".

In negative responses by-effects in the form of reddening and gripes in eyes, an intolerable itch and conjunctivitis because of which drug was cancelled are noted. Also its high cost is noted.


  • Glauprost 0,005% of a drop eye 2,5ml bottle-kapelnitsak.o. Romfarm of the Company of Neuter. L.
  • Glauprost 0,005% of a drop eye 2,5ml No. 3 bottle-kapelnitsyk.o. Romfarm of the Company of Neuter. L.

Drugstore of IFC

  • Glauprost 0.005% 2,5ml fl. - a cap., S.C.Rompharm Company S.r.L.Румыния
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Section: For eyes
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Education: Graduated from Sverdlovsk medical school (1968 - 1971) as "Paramedic". Graduated from the Donetsk medical institute (1975 - 1981) as "An epidemiologist, a hygienist". Passed postgraduate study in the Central scientific research institute of epidemiology Moscow (1986 - 1989). An academic degree – the candidate of medical sciences (degree is awarded in 1989, protection – the Central scientific research institute of epidemiology Moscow). Numerous advanced training courses are studied in epidemiology and infectious diseases.

Experience: Work as the manager of department of disinfection and sterilization of 1981 - 1992. Work as the manager of department of especially dangerous infections of 1992 - 2010. Teaching activity at Medical institute 2010 - 2013.

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