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Structure of IRS 19
43,27 ml of mix of lysates of the below-stated bacteria are a part of 100 ml of drug IRS 19: Klebsiella pneumonia, Streptococcus pneumoniae (types 1, 2, 3, 4), Acinetobacter calcoaceticus, Streptococcus pneumoniae (types 2, 3, 5, 8, 12), Streptococcus pyogenes A-группы, Haemophilus influenzae B-type, Staphylococcus aureus, Moraxella catarrhalis, Enterococcus faecalis, Neisseria subflava and perflava, Streptococcus dysgalactiae C-group, Enterococcus faecium, Streptococcus G-группы.
Additional substances: mertiolit sodium, glycine, water, fragrance on the basis of nerol.
Transparent, yellowish liquid without color with a slight characteristic smell.
20 ml of liquid in a glass aerosol can; one cylinder with the sprayer and a nozzle in a box from a cardboard.
Pharmacodynamics and pharmacokinetics
Drug of an immunopromoting effect on the basis of lysates of bacteria. Strengthens specific and nonspecific types of immunity.
When spraying medicine the aerosol which envelops mucous a nose that leads to active development of a local immune response is formed. Such protection is caused by locally formed antibodies like secretory immunoglobulins A interfering strengthening and reproduction of activators on a mucosal surface.
Nonspecific protection is shown in strengthening of phagocytal activity of cells macrophages and increase of maintenance of a lysozyme.
Indications to use
Use of drug is caused at following situations:
- prevention of chronic respiratory diseases;
- recovery of a local immune response after the postponed viral diseases;
- therapy of respiratory diseases of acute and chronic character (sinusitis, rhinitis, tracheitis, laryngitis, tonsillitis, pharyngitis, bronchitis);
- preparation for planned operation on ENT organs and recovery in the postoperative period.
- Autoimmune frustration.
- Hypersensitivity to medicine components.
- Pregnancy and lactation.
- Age less than 3 months.
Side effects can be both are caused, and not caused by administration of drug. At emergence of stated below signs consults to see a doctor.
- Dermatological reactions: Werlhof's disease, ekzemopodobny and eritemopodobny reactions, knotty erythema.
- Allergic reactions: Quincke's edema, small tortoiseshell.
- Frustration from respiratory system: laryngitis, nasopharyngitis, asthma attacks, sinusitis, cough, bronchitis.
- Frustration from digestion: vomiting, nausea, diarrhea, abdominal pain.
- Other frustration: a hyperthermia without the visible reasons.
Application instruction of IRS 19 (Way and dosage)
Medicine is applied intranazalno, spraying 1 dose of an aerosol by one short pressing upper part of a spray.
IRS 19 spray, application instruction
For the purpose of the prevention of infections for children and adults recommend 1 dose of medicine in each nasal pass twice a day for 2 weeks (it is recommended to begin several weeks prior to the expected epidemic rise).
For therapy of acute and persistent infections of respiratory tracts to children of 3-36 months appoint one dose of medicine in each nasal pass twice a day after preliminary cleaning of slime and so before disappearance of symptoms of an infection. To all other age categories of persons appoint on 1 dose in each nasal pass of 2-4 times a day before disappearance of symptoms of an infection.
For recovery of local immunity after respiratory viral diseases recommend to children and adults on 1 dose in each nasal course twice a day for 2 weeks.
For carrying out preparation for planned operation and at recovery in the postoperative period recommend to children and adults on 1 dose in each nostril twice a day within two weeks (it is recommended to begin therapy in 7 days prior to operation).
Rules of use of drug
For the correct work of an aerosol can it is necessary to put on a nozzle from above a cylinder and to press softly it. Then the device is ready to use.
When spraying drug the bottle needs to be held only in vertical position, the patient should not throw back the head.
At continuous use of medicine it is not recommended to disconnect a nozzle from a bottle.
The formed crystals close outlet opening of a bottle if to leave medicine for long time without use. If there was a similar obstruction of a nozzle, then it is necessary to make several pressing that under the influence of a high pressure the mouth was cleared; in the absence of effect it is recommended to lower a nozzle in warm water for several minutes.
There is no information on overdose cases.
Cases of negative interaction of drug with other medicines are unknown.
At identification of symptoms of an infection of bacterial genesis purpose of antibacterial drugs against the continuing use of IRS 19 is authorized.
Terms of sale
To protect from children. To store only in vertical position at the room temperature; not to freeze.
Bottle it is necessary to protect from heating more than 50 °C and from action of direct sunshine. It is forbidden to puncture a cylinder or to set fire to it even if it is devastated.
Period of validity
In the first week of treatment there can be a sneezing and allocations from a nose. These phenomena are usually not long-term. If these reactions amplify, then it is necessary to reduce number of introductions of medicine or to cancel it.
Also seldom in an initiation of treatment increase in body temperature over 39 °C is possible. In that case medicine needs to be cancelled.
However it is necessary to carry out differential diagnosis between such state and temperature increase, connected with development of diseases of ENT organs.
At emergence of clinical signs of a bacterial infection purpose of antibacterial drugs against the continuing use of IRS 19 is authorized.
At prescription of medicine to persons with bronchial asthma increase of attacks is not excluded. It is in that case recommended to stop treatment and not to use drugs of this type in the future.
Analogs of IRS 19: Bronkho-Vaksom.
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