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The structure of 1 tablet includes:
- kagotset (the main biologically active component) – 12 mg;
- potato starch – 10 mg;
- calcium stearate – 0,65 mg;
- ludipress (the lactose of direct pressing representing mix of monohydrate of lactose, povidone (kollidon 30) and a krospovidona (kollidon CL)) – to 100 mg.
In pharmaceutical booths medicine can be found in a form of biconvex round tablets of cream or brown color with small impregnations. The planimetric cell blister contains 10 pieces. 1 plate is put in cardboard packaging.
Kagotsel (MNN – the International unlicensed name) – antiviral drug which represents the synthetic complex organic salt of sodium received by synthesis from soluble in Karmoksimetiltselyulloza and Polifenol's water of seeds of the Cotton. That is a certain share of vegetable connections is the cornerstone of biologically active component of medicine.
As the interferon inductor, Kagotsel possesses the following therapeutic properties:
- radio tire-tread.
Wikipedia, the free encyclopedia of knowledge on Internet open spaces, claims that the mechanism of effect of pharmaceutical drug is extremely simple. It is based on ability of components of medicine to stimulate formations of different types of interferon, natural proteins defenders of an organism as specific protein structures activate enzymatic systems for oppression of harmful microflora and virus colonies. Also interferona are capable to suppress tumoral activity in its rudiment. The sphere of influence of Kagotsel extends on macrophages, T - and V-lymphocytes, granulocytes, endothelial cells and even fibroblasts.
Pharmacodynamics and pharmacokinetics
On passing of days (24 hours) from the moment of Kagotsel's introduction to an organism, the main biologically active components of medicine collect in tissues of a liver, lungs, a thymus gland, a spleen, kidneys and lymph nodes, that is bodies which in a varying degree show immune properties in relation to the harmful pathogens coming from the outside. Low concentration of the making elements of drug is observed in a myocardium of heart and other muscles, fatty tissue, seed plants, head a brain and a blood plasma.
The interferon caption in serum raises gradually and reaches the maximum figures in 48 hours after use of tablets. In intestines of the loudspeaker of accumulation of antiviral proteins is much higher – the maximum of products of interferon is noted in 4 hours. Therefore it is recommended to trace efficiency of use of medicine by means of research of contents of a gleam of a digestive tube and activity of its cellular structures.
The therapeutic effect is characterized as long as the answer of interferon remains within 4-5 days for which protective proteins continue to circulate in a blood-groove of the main and small vessels. Thanks to this property the greatest efficiency at conservative treatment by pharmaceutical drug is observed at its appointment no later than the 4th day from the beginning of an acute course of infectious process.
Indications to use
- acute respiratory viral infections;
- prevention of catarrhal diseases;
- herpes simplex at adult category of patients.
- the increased individual sensitivity to compound components of pharmaceutical drug;
- period of pregnancy and breastfeeding;
- the hereditary or acquired intolerance of medicine;
- age category of patients till 3 flyings;
- enzymatic disturbances of the alimentary system – deficit of lactase, a lactose intolerance, glyukozo-galaktozny malabsorption.
Adverse effects from use of medicine develop extremely seldom and are, as a rule, limited to allergic reactions. However if the patient observes at himself any side effects of active components of pharmaceutical drug, it is necessary to see immediately behind consultation the qualified doctor.
Application instruction of Kagotsel (Way and dosage)
Tablets Kagotsel, application instruction
The producer specifies in the summary that it is necessary to use medicine orally, without chewing a tablet, and swallowing of it entirely. It is possible to wash down with enough liquid, however not to keep it long in an oral cavity. The dosage and duration of treatment, as a rule, are selected in individually empirical way, but also there are general therapeutic schemes which have to be considered by the attending physician as practical recommendations.
How to drink for adults?
With the therapeutic purpose at acute respiratory viral infections, flu or grippopodobny diseases appoint 2 tablets 3 times a day in the first 2 days, and the next 2 days on 1 tablet 3 times a day. A course dosage – 18 tablets, and treatment duration – 4 days. How to accept – to food or after – for an adult organism has no practical value as vsasyvatelny abilities of biologically active components of pharmaceutical drug do not change with receipt of food in a digestive tract cavity.
Medicine can be used also as preventive, preventive sanitation which is carried out by 7-day cycles. The course is divided into two phases. The first, active when about 2 tablets once a day for 2 days are appointed, and the second, passive, represents a 5-day break (for which time the operating components are capable to implement the therapeutic effects). Then, if necessary, it is possible to repeat a preventive course of treatment.
The application instruction for children
In an age category from 3 to 6 years – on 1 tablet 2 times a day in the first 2 days, and in the next 2 days on 1 tablet of 1 times a day. Total the children's therapeutic course for the smallest makes reception lasting 6 tablets in 4 days.
At the age of more than 6 years appoint on 1 tablet 3 times a day in the first 2 days, and in the next 2 days – on 1 tablet 2 times a day. Respectively duration of conservative sanitation did not change and makes 4 days, and the dosage of pharmaceutical drug grew to 10 tablets.
Medicine can be used with the preventive purpose and in pediatric practice. The two-phase scheme of administration of drug remains, however the dosage decreases to 1 tablet for the first 2 days once a day.
How to accept Kagotsel at herpes?
As pharmaceutical action of Kagotsel extends to viruses and immune system, respectively medicine can be used by adult category of patients not only for treatment of catarrhal diseases of a virus etiology, but also for elimination of unpleasant herpetic rashes. How to drink tablets at herpes – about 2 tablets 3 times a day for 5 days are appointed. A course dose – 30 tablets.
As well as side effects, a clinical condition of overdose it is observed very seldom and is followed by attacks of nausea and pain in upper part of a stomach. In case of the specified symptoms it is recommended to clear a digestive tract of tablets Kagotsel by means of artificially caused vomiting. Further plentiful drink and some other elements of disintoxication therapy is appointed.
Clinically significant interactions are at the moment not revealed and not described in medical literature.
Terms of sale
The summary to medicine claims that tablets are in free access in pharmaceutical booths, that is it is possible to buy drug without the corresponding recipe.
To preserve tablets in the place, unavailable to children, at a temperature not above 25 degrees Celsius.
Period of validity
Kagotsel is an antibiotic or not?
Medicine has strong antimicrobic, antiviral and immunomodulatory therapeutic effects from what tablets can be perceived by inhabitants as an antibiotic. But from clinical pharmacology it is not absolutely right, in definition of this group of pharmaceutical products the natural or semi-natural origin of the operating components is key. Kagotsel, in turn, is a synthetic derivative of vegetable components that allowed scientists-researchers to combine the best qualities of anti-cold drugs in one tablet.
Coincidence on the ATH code of the 4th level:
Antiviral medicines – extremely big group of pharmaceutical products which, as a rule, in pharmaceutical booths occupies not one shelf respectively Kagotsel has very wide list of analogs (analogs are meant as drugs with the identical international unlicensed name or a similar code of the ATH system). For Kagotsel's replacement can be used: Aveol, Aqua Maris, Bitsiklol, Vazonat, Glitsiram and many others.
Kagotsel treats expensive antiviral tablets therefore separately it is necessary to consider a question of whether there is Kagotsel's analog cheaper or not. The answer considerably depends on the country of accommodation and acquisition of drug. So, for example, in Ukraine as medicine from respiratory diseases Abjyufen, Avioplant, Atoksil, Bronkhostop whose cost varies depending on pharmacy chain can be used, however always remains below market price of Kagotsel. In more available analog Anaferon acts.
Also as Kagotsel's analogs many pharmaceutical drugs which possess not identical therapeutic action are considered, however are similar in a net result to cold antiviral medicine.
That it is better: Kagotsel or Ingavirin?
Ingavirin is the pharmaceutical drug, popular in winter time, which is characterized by the expressed antiviral action concerning the most frequent causative agents of acute respiratory diseases such as an influenza virus of type A and B and steam of flu, respiratory and syncytial group of viruses, adenovirus and many others. The mechanism of its action is based on a possibility of biologically active components to influence processes of a reproduction and resuming of harmful agents. Also attribute to medicine in the form of capsules strong antiinflammatory influence on a human body.
Undoubtedly, pharmaceutical drug is effective during conservative sanitation of catarrhal diseases with the confirmed activator origin, however as not specific therapy when it is not possible to install an etiological component of pathology, Ingavirin's use is not rational. Kagotsel wins and in a different way to point, namely preventive measures, medicine is actively applied to prevention of development of respiratory infections during the winter period, than, unfortunately, Ingavirin cannot brag.
That it is better: Kagotsel or Arbidol?
Arbidol, as well as Kagotsel, is antiviral drug which therapeutic expediency of use consists in increase of products of the natural interferon confronting an invasion of pathological agents. In addition the operating components of medicine stimulate cellular and humoral reactions of immunity that positively affects resistance of an organism to viral respiratory infections.
The list of side effects of Arbidol so short, as well as at Kagotsel, but in difference from the last, pharmaceutical drug is included in the list B (the register of medicines which purpose has to be made with extra care as development of unexpected complications at their use without careful medical supervision is possible) that in itself guards. If the decision to pass conservative therapy or preventive sanitation "standing" (without registration of the official sick-list) is made, then unambiguously it is necessary to choose Kagotsel.
That it is better: Kagotsel or Amiksin?
Amiksin is the effective synthetic inductor of interferon, that is on the mechanism of action Kagotsel as drug increases education of the active antiviral agent intestines epithelium cells, hepatocytes, some fractions of lymphocytes is similar to tablets. Distinctive feature of Amiksin is a speed of occurrence of therapeutic effects, soft immunomodulatory action is observed in 4-24 hours after medicine reception. According to its use is more rational in urgent conservative sanitation of patients of an adult age category.
In pediatric practice pharmaceutical drug did not gain so wide popularity as in the summary there is a contraindication to use of tablets Amiksin till 7 flyings. Means, at treatment of children of a younger age segment the preference should be given to Kagotsel whose use can be begun since 3.
Kagotsel or Ergoferon — what is better?
Ergoferon is a medicine with extraordinary wide range of therapeutic action which, in addition to selective antiviral and immunomodulatory effects, includes antihistaminic and antiinflammatory components. Clinical rationality of use of pharmaceutical drug is proved on many points. So, for example, the list of causative agents of respiratory infectious diseases which are prostrate after use of tablets Ergoferon much more, than at Kagotsel.
Separately it should be noted that Ergoferon can be applied, as in therapeutic practice for adult patients, and in pediatrics, since age in 6 months. Proceeding from these facts, pharmaceutical drug it is possible to recognize better than Kagotsel, but also the price of analogs of such level, of course, higher.
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