Karsil Forte

Карсил Форте Drug photo

The description is actual on 17.03.2016

  • Latin name: Carsil forte
  • ATH code: A05BA03
  • Active ingredient: Thistles spotty fruits extract (Silybi mariani fructuum extract)
  • Producer: Sopharma AD (Bulgaria)

Structure

Extract of fruits of a thistle dry, lactoses monohydrate, cellulose microcrystallic, talc, starch wheat, povidone, glucose monohydrate, hydrosodium carbonate, magnesium stearate, sorbitol.

Release form

Capsules gelatinous 90 mg of light brown color in the blister on 6 capsules in cardboard packaging No. 30.

Pharmacological action

Gepatoprotektor.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

Drug on the basis of extract of fruits of a thistle which contains mix of isomers of flavonolignan (Silibininum, a silidianin, iso-Silibininum and a silikristin) has gepatoprotektorny effect. At the heart of the mechanism of action of Silymarinum — competitive action with toxins on receptors of hepatocytes. Silymarinum regulates a metabolism of cells and permeability of a cellular membrane and contacts free oxygen radicals. Drug stimulates synthesis of structural proteins and phospholipids in the hepatocytes affected with a virus accelerates regeneration processes. Action of flavonoids is in many respects caused by antioxidant action and improvement of processes of microcirculation. Clinically it is shown by normalization of function of a liver, improvement of the general condition of the patient.

Pharmacokinetics

Drug possesses slow absorption, does not collect in an organism. The maximum concentration of Silibininum are found in a liver and it is insignificant — in heart, kidneys, lungs. It is metabolized in a liver in the form of sulfates and glucuronides. The elimination half-life is brought about 6 hours to 80% with bile.

Indications to use

Treatment of damages of a liver of toxic genesis, not viral chronic viral hepatitis, states after an acute hepatitis, cirrhosis and a steatosis of a liver.

It is appointed also for prevention of damages of the liver at an alcohol abuse, long drug intake expressed to chronic intoxication.

Contraindications

Individual hypersensitivity to Karsil Forte, a galactosemia, insufficiency of lactase, age till 12 flyings, pregnancy and the period of a lactation.

To appoint with care in the presence of hormonal disturbances (a hysteromyoma, a cancer of ovaries, a prostatic and mammary gland).

Side effects

Dyspepsia, nausea, diarrhea, local allergic reactions, vestibular disturbances. Side effects, as a rule, after the termination of reception of Karsil completely disappear.

Application instruction Karsil Forte (Way and dosage)

To adults and children after 12 flyings for treatment of a serious illness of a liver appoint on 1 capsule inside, washing down with water 3 times a day and on 1 capsule 2 times a day at easy and moderately severe defeats. It is recommended to accept drug for 3 months.

The instruction on Karsil Forte indicates the need of preventive administration of drug on 1 capsule a day at potentiality of development of medicinal and chemical intoxication.

Overdose

About overdose of drug there are no data.

Interaction

Karsil Forte strengthens action of a number of HP (Diazepam, Vinblastine, Ketokonazol, Alprazolam, Lovastatin).

At purpose of Silymarinum together with oral contraceptives decrease in efficiency of their action is noted.

Terms of sale

According to the recipe.

Storage conditions

In the dry place at a temperature up to 25 °C.

Period of validity

2 years.

Analogs

Levasil, Legalonum, Geparsil, Silymarinum, Geksal, Siliborum.

About Karsil Forte

About drug favorable:

  • "… Excellent medicine, at the same time natural and is much cheaper than analogs. Accepted more expensive drugs, but the same effect, so why to overpay. After Karsil Forte's reception I improve health, in right the hypochondrium disappears discomfort, the bitterness vanishes in a mouth".

Many of forumites write that they accept drug with the preventive purpose after holidays which are followed plentiful meal and alcohol.

Karsil Forte, responses of doctors: drug is effective in therapy of acute and chronic hepatitis, chronic cholecystitis, dyskinesia of a gall bladder. It is appointed at cirrhoses of a liver and hepatitises for prevention of progressing of negative process.

Zdravzona

  • Karsil Forte of 90 mg No. 30 of a kapsulysofarm of the joint-stock company

Drugstore of IFC

  • Karsil forte kaps 90 mg No. 30, Sopharma Jscbolgariya
to show still

Apteka24

  • Karsil forte capsules 90 mg No. 30sofarma (Bulgaria)

Paniapteka

  • Karsil forte kaps. 90 mg No. 30
Section: For a liver
in more detail

Education: Graduated from Sverdlovsk medical school (1968 - 1971) as "Paramedic". Graduated from the Donetsk medical institute (1975 - 1981) as "An epidemiologist, a hygienist". Passed postgraduate study in the Central scientific research institute of epidemiology Moscow (1986 - 1989). An academic degree – the candidate of medical sciences (degree is awarded in 1989, protection – the Central scientific research institute of epidemiology Moscow). Numerous advanced training courses are studied in epidemiology and infectious diseases.

Experience: Work as the manager of department of disinfection and sterilization of 1981 - 1992. Work as the manager of department of especially dangerous infections of 1992 - 2010. Teaching activity at Medical institute 2010 - 2013.

PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use Karsil Forte surely consult with the attending physician.