Cavintonum Forte

Кавинтон Форте Drug photo

The description is actual on 31.08.2015

  • Latin name: Cavinton Forte
  • ATH code: N06BX18
  • Active ingredient: Vinpocetine
  • Producer: JSC Gideon Richter (Hungary)


1 tablet contains 10 m of a Vinpocetine – active drug.

Additional ingredients: talc, magnesium stearate, colloid silicon dioxide, monohydrate of lactose, starch corn.

Release form

The company Gideon Richter lets out Cavintonum Forte in the form of tablets on 30 or 90 pieces in a pack.

Pharmacological action

The improving blood circulation of a brain, vasodilating, neuroprotective, anti-hypoxemic, anti-aggregation.

Pharmacodynamics and pharmacokinetics

Cavintonum Forte is medicine which effect directionally on improvement of a brain metabolism, and also increase in consumption by tissues of a brain of oxygen and glucose. The Vinpocetine strengthens the resilience of neurons of a hypoxia, increases delivery of glucose to brain tissues through GEB, will transform glycolysis to more energetically economical process of aerobic disintegration of glucose, selectively blocks kaltsiyzavisimy FDE. Increases in a brain of concentration of tsGMF and AMF, content of ATP and a relative ratio of ATP/AMF, raises fabric an exchange of serotonin and noradrenaline, activates formations of cells of the ascending noradrenergichesky system, possesses antioxidant efficiency. Reduces ability of thrombocytes to aggregation and rarefies blood, increases the deforming properties of erythrocytes and interferes with utilization of adenosine by them, promotes increase in return by oxygen erythrocytes. Expands neuroprotective effects of adenosine. Raises a cerebral blood stream and reduces vascular resistance of a brain, at the same time, significantly without influencing system blood circulation (including the ABP, ChSS, minute volume, the general peripheral resistance). It is not characterized by effect of burglarizing, and even increases blood supply, in particular in ischemic regions of a brain with hypoperfusion.

At oral administration the Vinpocetine is soaked up by the most part in proximal departments of a gastrointestinal tract. Average Tmax equals to 60 minutes. Does not give in to metabolic transformations when passing through intestines walls. Fabric Cmax is observed after 2-4 hours. Communication with plasma proteins – 66%, bioavailability near – 7%. It is metabolized out of a liver what its clearance – 66,7 l/h, the exceeding hepatic plasma volume (50 l/h) testifies to. At further oral administration in the range of doses of 5-10 mg the linear kinetics of drug is traced. It is removed by intestines and kidneys in the ratio 2:3. T1/2 fluctuates within 4-6 hours.

Indications to use Cavintonum Forte

Indications to use of drug include conditions of insufficiency of cerebral circulation where Cavintonum is used Forte for the purpose of decrease in symptomatology of mental and neurologic disorders. Treat these states: the rehabilitation period after an ischemic stroke, a recovery stage after a hemorrhagic stroke, postinsultny complications, atherosclerosis of brain vessels, vascular dementia, tranzitorny ischemic attack, vertebrobazilyarny insufficiency, hypertensive/posttraumatic encephalopathy.

In otorhinolaryngology use of HP for therapy of idiopathic ear noise, Menyer's illness and states proceeding with decrease in hearing of perceptual character is shown.

Also drug is used at chronic vascular pathologies of organs of sight, including damages of a retina of eyes and their choroid.


Side effects

Cardiovascular system:

  • feeling of inflow;
  • changes on an ECG (lengthening of a QT interval, ST depression);
  • lability of the ABP;
  • ekstrasistoliya;
  • tachycardia.

Nervous system:

Alimentary system:

  • dryness in an oral cavity;
  • eructation/heartburn;
  • feeling of nausea.

Cavintonum Forte, application instruction

The application instruction Cavintonum Forte recommends internal (peroral) reception of tablets HP, after food.

Duration of treatment and sufficient dosages of drug are appointed by the doctor proceeding from an individual situation.

As a rule, a pill is taken three times at 24 o'clock in a dose of 5-10 mg. It is necessary to begin therapy with a daily dose in 15 mg, with its increase, if necessary, up to the most admissible daily dose in 30 mg. The therapeutic effectiveness of treatment is observed in 7 days, and the full-fledged effect of therapy demands administration of drug for 3 months.

Pathologies of livers/kidneys do not demand correction of the dosing mode.


For this time of the data on overdose are not provided in full, however in case of reasonable suspicion on reception of the overestimated doses of drug and dependent emergence of the undesirable phenomena it is necessary to undertake the standard methods / schemes of therapy used in such circumstances (induction of vomiting, clarification of a gastrointestinal tract, reception of sorbents, etc.).


The combined use with Metildopoy sometimes led to some strengthening of hypotensive effect in this connection at such combination it is required to control the ABP constantly.

At parallel use with Imipraminum, Clopamidum, Pindololum, Glibenclamidum, Atsenokumarol, Digoxin and the Hydrochlorothiazide of significant interactions it was not observed.

Judging by effects of a Vinpocetine, its joint appointment with drugs of antiarrhythmic, central and anticoagulating action should be carried out with care though today data on similar interactions are absent.

Terms of sale

Cavintonum Forte can be released only according to the recipe.

Storage conditions

Restriction of temperature condition of storage of tablets makes 15-30 °C.

Period of validity

From the moment of production – 5 years.

Special instructions

In case of diagnosing at the patient of a lactose intolerance it is necessary to pay attention to contents in 1 tablet of 83 mg of monohydrate of lactose.

When passing therapy by patients with a syndrome of the prolonged QT interval or parallel reception of the HP leading to lengthening of a QT interval it is necessary to exercise control of an ECG periodically.

Analogs Cavintonum Forte

Analogs of drug similar to it by the main efficiency:


  • Cavintonum forte 10 mg No. 30 tabletkigedeon Richter
  • Cavintonum forte 10 mg No. 90 tabletkigedeon Richter

Drugstore of IFC

  • Cavintonum forte tbl 10 mg No. 30, Gedeon Richter/Gideon-Richter-RUS Zaorossiya
  • Cavintonum forte tbl 10 mg No. 90, Gedeon Richter/Gideon-Richter-RUS Zaorossiya
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  • Cavintonum forte tablets 10 of mg No. 30 Gideon Richter (Hungary)
  • Cavintonum forte tablets 10 of mg No. 90 Gideon Richter (Hungary)


  • Cavintonum Forte 10 mg No. 30 of table.
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Section: For a nervous system Cardiovascular
in more detail

Education: Graduated from the Vinnytsia national medical university of N. I. Pirogov, pharmaceutical faculty, the higher pharmaceutical education – the specialty "Pharmacist".

Experience: Work in Koneks and Bios-Media pharmacy chains as "Druggist". Work as "Pharmacist" in Avicenna pharmacy chain of the city of Vinnytsia.

PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use Cavintonum Forte surely consult with the attending physician.