Ketoprofen

Кетопрофен Drug photo

The description is actual on 21.02.2015

  • Latin name: Ketoprofen
  • ATH code: M02AA10
  • Active ingredient: Ketoprofen (Ketoprofen)
  • Producer: Vetpry ABP (Bulgaria)

Structure

Ketoprofen contains in 100 grams of ointment 2,5 grams of the medicinal active connection of the same name, and also such auxiliary connections as ethanol, water, 940 karbopol, methylparahydroxybenzoate or nipagin and trolamin.

Release form

Medicine is let out in the form of ointment or the gel Ketoprofen having a homogeneous consistence, the transparent or light yellow shade intended for external use. Besides, there are subspecies of this drug in the form of tablets, candles, and also solution for intramuscular and intravenous administration.

2,5% package gel in specialized tubas from aluminum foil or polyethylene on 50 grams in everyone, and place in cardboard packagings on 1 piece.

Pharmacological action

Ointment Ketoprofen belongs to group of so-called NPVP of drugs, i.e. nonsteroid antiinflammatory medicines.

Pharmacodynamics and pharmacokinetics

At use ointment Ketoprofen shows the analgeziruyushchy and antiinflammatory properties. Actively operating medicinal component which is a part of drug promotes suppression of the 1, 2 cyclooxygenase activity, as a result regulating synthesis of prostaglandins.

When using gel in treatment of a joint syndrome it is possible to reduce considerably pain of patients as at the movement, and at rest, and also to lower a swelling of joints and to eliminate their morning constraint. During local use ointment is rather slowly soaked up and does not kumulirutsya in a human body.

Bioavailability of Ketoprofen is at the level of 5%. Drug does not form metabolites of active type and is metabolized at conjugation with glucuronic acid.

Indications to use

On a question from what ointment Ketoprofen is effective, it is possible to answer the next way - drug is shown to use at the following indispositions and diseases:

  • musculoskeletal system diseases, for example, rheumatism, joint syndrome, gout, arthritis (rhematoid, psoriasis types), osteoarthrosis, spondylarthritis ankylosing, osteochondrosis, radiculitis, sciatica, damage of sinews and linking of inflammatory type, lumbago;
  • pains in muscles of not rheumatic and rheumatic origin;
  • inflammations of soft tissues of posttraumatic character, for example: gaps, bruises and other injuries of ligaments and musculoskeletal system.

Contraindications

It is not recommended to apply this medicine at the dermatosis which is becoming wet, wounds and the infected grazes, eczema, at hypersensitivity, and also during pregnancy and breastfeeding. To all other, it is not necessary to use Ketoprofen in treatment of the children who did not reach 12 summer age.

Side effects

At external use of ointment side effects arise extremely seldom on condition of observance of all instructions on a drug dosage. However such side effects of medicine as meet: allergic reactions, purpura, skin dieback, hyperemia, and also photosensitization, itch and burning sensation.

Application instruction of Ketoprofen (Way and dosage)

Gel Ketoprofen, application instruction

Ointment is used only outwardly, i.e. apply on integuments with the easy massing movements by a strip about 4-6 cm in the field of an inflammation and presence of pain. The course of treatment drug (without preliminary medical consultation and inspection) should not exceed 10 days.

Ketoprofen tablets, application instruction

The dosage of drug has to be established by the attending physician individually in each case. The initial daily recommended drug dose for adult patients makes 300 mg. Ketoprofen is accepted by at most 3 times a day.

At reception drug inside there can be such side effects as: nausea, a lock, vomiting or diarrhea, a gastralgia, pain in epigastric area, headaches, disturbances of functions of kidneys and a liver, dizziness, allergic reactions, a sonitus, damages of a gastrointestinal tract of ulcer or eroziyny character.

Candles Ketoprofen, application instruction

The recommended daily dosage when using rectal suppositories should not exceed 300 mg. It is contraindicated to use candles in the presence of proctorrhagias, and also a proctitis (even in the anamnesis).

Pricks (Ketoprofen solution for intravenous or intramuscular administration) use for the emergency stopping of sharpening of chronic character, and also at treatment of acute states in the single dosage which is not exceeding 100 mg. As a rule, further treatment of patients is continued by other forms of drug.

Overdose

At external use of drug overdose is almost impossible because of low system absorption of compound components of Ketoprofen.

Interaction

Ketoprofen with other drugs is not present data on medicinal interaction of ointment.

Terms of sale

Gel can be bought in a drugstore without recipe.

Storage conditions

Ketoprofen is entered in the list of drugs B, therefore it is necessary to store medicine at a temperature of 15-25 With, it is desirable in the dark and dry place, surely hardly accessible for children.

Period of validity

2 years.

Special instructions

Ointment is strictly forbidden to be applied on wounds or the inflamed integuments. It is necessary to avoid hit of drug on mucous membranes. After putting gel Ketoprofen it is necessary to wash up hands carefully. It is strictly forbidden to use this medicine with air-tight or occlusive bandages.

Analogs of Ketoprofen

As analogs of Ketoprofen it is possible to consider such drugs as: Artrozilen, Arketal Romfarm, Artrum, Ketonal, Bystrumgel, Valusal, Ketoprofen Organic chemistry, Ketoprofen Vramed, Ketoprofen forte, MV Ketoprofen, Ketoprofen-Verte, Ketospry, Ketoprofen-ESKOM, OKA, Profenil, Oruvel, Fastum, Flamaks, Fastum gel, Fleksen, Febrofid.

Zdravzona

  • Ketoprofen-verte 2,5% gel 30gverteks of closed joint stock company
  • Ketoprofen-vramed 2,5% gel 40gsofarma of the joint-stock company
  • Ketoprofen 50mgml solution for injections of 2 ml No. 10 ampulysintez joint stock company
  • Ketoprofen-verte 2,5% gel 50gverteks of closed joint stock company
  • MV ketoprofen 150 of mg No. 20 tabletkibioky closed joint stock company

Drugstore of IFC

  • Ketoprofen-verte gel of 2.5% 50 g, Zaorossiya's Vertexum
  • Ketoprofen-verte gel of 5% 30 g, Zaorossiya's Vertexum
  • Ketoprofen gel of 2.5% 50 g, Vetpry Adrossiya
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BIOSPHERE

  • Ketoprofen of 2,5% 50 g gel for an external comment the Vetpry ABP (Bulgaria)
  • Ketoprofen Romfarm of 50 mg/ml 2 ml No. 10 solution for in oil and in/in introductions
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Section: For joints
PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use Ketoprofen surely consult with the attending physician.