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Ketotifenum
Structure
Active agent is Ketotifenum in the form of Ketotifenum of a fumarat.
The tablets Ketotifenum contain 1 mg of active ingredient. Additional substances: monohydrate of lactose, starch, magnesium stearate.
Syrup contains 1 mg / 5 ml of active ingredient.
Eye drops contain 0,25 mg/ml of active ingredient. Additional substances: sodium hydroxide, chloride a benzalkoniya, Trilonum of B, a dextran, sodium chloride, water the purified, citric acid.
Release form
Medicine is issued in the form of syrup, tablets and eye drops.
Pharmacological action
Drug has pronounced antihistaminic effect. This means from group of antiasthmatic nebronkhodilatiruyushchy medicines.
Pharmacodynamics and pharmacokinetics
Drug works as follows: it brakes release of a histamine, and also other mediators from mast cells, also it blocks histamine H1 receptors, at the same time oppressing FDE enzyme. As the result of these actions, increases in mast cells the tsAMF level. Ketotifenum affects podavlyayushche effects of a platelet activating factor. If drug is used independently, then attacks of bronchial asthma are not stopped. At the same time drug anticipates them to emergence and considerably reduces intensity and duration of these attacks. In some cases they stop completely. In a blood plasma the maximum concentration of drug is observed 2–4 hours later. Metabolization of the most part of a dose of means occurs in a liver.
Indications to use of Ketotifenum
From what these tablets, and for what syrup and eye drops?
Medicine is used as an additional tool in the course of long therapy of atopic bronchial asthma. Also the indication to use of Ketotifenum are a number of allergic states among which there is conjunctivitis and rhinitis of allergic type.
Contraindications
Cannot use drug the patients having high sensitivity to acting or to auxiliary components of Ketotifenum. Administration of drug in the first trimester of pregnancy is prohibited, and also during feeding by a breast.
Side effects
During treatment by this medicine some side effects can develop. Rather often there is a condition of drowsiness, dryness in a mouth, the increased drowsiness, dizzinesses. Problems with a gastrointestinal tract – locks, nausea, vomiting can be observed. These phenomena disappear spontaneously in the course of treatment. Also to a type of the increased appetite weight can increase. There are symptoms of irritability and excitement, hypersensitivity less often. At children emergence of spasms is possible. Rather seldom there can be hepatitis, cystitis, jaundice, dark coloring of urine. At overdose drowsiness, hypotension, dizziness, vomiting and nausea, spasms at children can be shown. In this situation the urgent gastric lavage and reception of symptomatic means is necessary.
Application instruction of Ketotifenum (Way and dosage)
Tablets Ketotifenum, application instruction
Use during reception of food, wash down with a small amount of water. One tablet contains 1 mg of drug. Adults accept on one tablet twice a day. Those patients at whom manifestation of the expressed sedation takes place have to raise a drug dose gradually. It becomes for seven days, it is necessary to begin with 0,5 mg. This dose before going to bed is accepted, and gradually the amount of drug rises to a therapeutic dose. Children are more senior than three years accept on 1 tablet twice a day – in the morning and in the evening. Administration of drug is carried out similarly to food time.
Ketotifenum of Sofarm is used similarly.
Syrup Ketotifenum, application instruction
Children from a year to three years can accept Ketotifenum only in the form of syrup which is appointed in a dose of 0,25 ml to kg of mass of the child twice a day. Children of 3 years should use 5 ml of syrup two times a day with food.
The instruction on drops eye
Since 3 years it is possible to dig in on one drop twice a day in a conjunctival sac.
Treatment by Ketotifenum takes the long period. At the same time the noticeable effect after its reception will be reached after 2-3 weeks of therapy. The general course of treatment can make two-three months. Especially long period those patients at whom the visible effect in several weeks of reception of a medicine was not observed have to accept this medicine. Treatment by this means stops gradually, for several weeks. It becomes in order to avoid recurrence of asthmatic symptoms.
Overdose
Data on overdose are absent. After the use of 20 mg of means any serious symptoms were not noticed.
Interaction
Can strengthen considerably influence of somnolent drugs, and also antihistamines and alcohol.
Terms of sale
The recipe is required.
Storage conditions
In the place, dry, dark, unavailable to children, at a temperature no more than 25 degrees Celsius.
Period of validity
No more than 3 years.
Special instructions
Drug is not used to stop asthmatic attacks. At the beginning of therapy by this means it is impossible to stop sharply treatment by other antiasthmatic drugs. Especially it concerns system GKS. At the people having steroid dependence adrenal insufficiency can develop.
This drug has a property to reduce a convulsive threshold, therefore, he is carefully appointed that patient at whom spasms are shown. During pregnancy this drug is appointed only when there are direct indications, and the advantage of its reception exceeds risk for the woman and a fruit. At administration of drug it is necessary to stop feeding by a breast. In view of possible manifestation of drowsiness Ketotifenum is recommended to apply very carefully to the drivers and people working with potentially dangerous units.
According to information of the website of Sportviki drug increases sensitivity beta-2 adrenergic receptors owing to what it is often applied in bodybuilding and to weight loss. We advise to consult at the doctor about a possibility of such use of a medicine.
For children
Instruction
Aged from a year to three drug is appointed in the form of syrup in a dose of 0,25 ml to kg of mass of the child twice a day. To children is more senior than 3 years about 5 ml of syrup or on 1 tablet and are offered to accept in the morning in the evening.
About Ketotifenum for children
Medicinal is effective when using at children. The medicine removes allergy attacks, however long reception is required. Side effects, for example, drowsiness are also possible.
Analog it is possible to call the medicine Zaditenum.
About Ketotifenum
Drug is considered an inexpensive effective remedy from allergic reactions. From minuses it should be noted duration of a course and side effects, especially — the increased drowsiness after use of a medicine.
Ketotifenum price
Ketotifenum price in tablets of 1 mg makes 50 rubles for a pack of 30 pieces.
Price of eye drops Ketotifenum of 170 rubles.
Syrup cost — 70 rubles.
It is possible to buy drug in Ukraine at the following prices:
- tablets — 10
- syrup — 20
- eye drops — 15
Zdravzona
- Ketotifenum of 1 mg No. 30 of a tabletkisofarm of the joint-stock companya class="drug-price-link" href="/javascript:if(confirm(%27medicalmed.us/goto/ad.admitad.com/g/ib5wu3w32j09dcb39bb44ff4e25399/?i=5&ulp=http%3A%2F%2Fwww.zdravzona.ru%2Fproduct%2Fketotifen-1mg-30-tab%2F \n\nThis file was not retrieved by Teleport Pro, because it is addressed on a path excluded by the site\%27s Robot Exclusion parameters. (Teleport Pro\%27s compliance with this system is optional; see the Project Properties, Netiquette page.) \n\nDo you want to open it from the server?%27))window.location=%27medicalmed.us/goto/ad.admitad.com/g/ib5wu3w32j09dcb39bb44ff4e25399/?i=5&ulp=http%3A%2F%2Fwww.zdravzona.ru%2Fproduct%2Fketotifen-1mg-30-tab%2F%27" tppabs="medicalmed.us/goto/ad.admitad.com/g/ib5wu3w32j09dcb39bb44ff4e25399/?i=5&ulp=http%3A%2F%2Fwww.zdravzona.ru%2Fproduct%2Fketotifen-1mg-30-tab%2F" target="_blank">
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Drugstore of IFC
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- Ketotifenum tbl 1 mg No. 30, Irbitsky HFZ (Irbit) Russiaa class="drug-price-link" href="/javascript:if(confirm(%27medicalmed.us/goto/ad.admitad.com/g/fa400bb23009dcb39bb46fa0457639/?i=5&ulp=http%3A%2F%2Fwww.apteka-ifk.ru%2Fart%2F54467%2F \n\nThis file was not retrieved by Teleport Pro, because it is addressed on a path excluded by the site\%27s Robot Exclusion parameters. (Teleport Pro\%27s compliance with this system is optional; see the Project Properties, Netiquette page.) \n\nDo you want to open it from the server?%27))window.location=%27medicalmed.us/goto/ad.admitad.com/g/fa400bb23009dcb39bb46fa0457639/?i=5&ulp=http%3A%2F%2Fwww.apteka-ifk.ru%2Fart%2F54467%2F%27" tppabs="medicalmed.us/goto/ad.admitad.com/g/fa400bb23009dcb39bb46fa0457639/?i=5&ulp=http%3A%2F%2Fwww.apteka-ifk.ru%2Fart%2F54467%2F" target="_blank">
- Ketotifenum tbl 1 mg No. 30, Pharmachim/Sopharmabolgariyaa class="drug-price-link" href="/javascript:if(confirm(%27medicalmed.us/goto/ad.admitad.com/g/fa400bb23009dcb39bb46fa0457639/?i=5&ulp=http%3A%2F%2Fwww.apteka-ifk.ru%2Fart%2F6936%2F \n\nThis file was not retrieved by Teleport Pro, because it is addressed on a path excluded by the site\%27s Robot Exclusion parameters. (Teleport Pro\%27s compliance with this system is optional; see the Project Properties, Netiquette page.) \n\nDo you want to open it from the server?%27))window.location=%27medicalmed.us/goto/ad.admitad.com/g/fa400bb23009dcb39bb46fa0457639/?i=5&ulp=http%3A%2F%2Fwww.apteka-ifk.ru%2Fart%2F6936%2F%27" tppabs="medicalmed.us/goto/ad.admitad.com/g/fa400bb23009dcb39bb46fa0457639/?i=5&ulp=http%3A%2F%2Fwww.apteka-ifk.ru%2Fart%2F6936%2F" target="_blank">
Apteka24
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BIOSPHERE
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Section: From an allergy
PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use Ketotifenum surely consult with the attending physician.