Klionum

Клион Drug photo

The description is actual on 21.04.2014

  • Latin name: Klion
  • ATH code: J01XD01
  • Active ingredient: Metronidazole (Metronidazole)
  • Producer: CJSC Gideon-Richter, Russia

Structure

One tablet of Klionum contains: metronidazole – 0,25 g + excipients (talc, corn starch, glitserol, srearat magnesium, colloid silicon dioxide, povidone).

Release form

Packagings with tablets on 10 pieces, on 2 in a pack.

Pharmacological action

Antiprotozoan means with antimicrobic action.

Pharmacodynamics and pharmacokinetics

The transport proteins of anaerobe bacterias which are in a cell recover 5-nitromidazol. The formed substance negatively influences DNA of cells (breaks processes of synthesis of nucleic acids). Microorganisms perish.

Shows antimicrobic activity in relation to gram-negative (Trichomonas vaginalis, Bacteroides distasonis, Giardia intestinalis, Prevotella) and to some gram-positive bacteria (naprimerpeptococcus spp. and Eubacterium spp.).

Medicine shows activity concerning anaerobic organisms. Does not influence anaerobe bacterias. But at complex treatment with antibiotics (for example amoxicillin) effectively destroys pernicious microflora.

Drug can strengthen separative processes and degree of sensitivity to radiation of new growths (tumors).

Metronidazole is well soaked up and about a half of substance is metabolized in many biological liquids. Reaches the maximum concentration within 2-3 hours, after reception.

Indications to use

  • the stomach ulcer or erosion caused by Helicobacter pylori bacterium;
  • state after operations within prevention;
  • trichomoniasis, lambliasis, skin leushmaniosis, balanthidiasis, amoebic abscess of a liver, amebiasis and other protozoan infections;
  • all types of diseases caused by Bacteroides, Peptostreptococcus, Clostridium, Peptococcus spp.;
  • colitis is pseudomembranous;
  • radiation therapy of patients with tumors.

Contraindications

  • epilepsy and other organic lesions in the central nervous system;
  • diseases of a liver and kidneys;
  • leukopenia;
  • medicinal allergy to substances as a part of Klionum;
  • pregnancy and period of breastfeeding.

Side effects

  • pancreatitis, lack of appetite, vomiting, nausea, smack of metal and dryness in an oral cavity, stomatitises;
  • headache, dizziness, weakness or opposite, excessive excitability, confusion of consciousness, ataxy, hallucinations;
  • cystitis, urine incontience, urine can get a reddish shade;
  • leukopenia;
  • allergic reactions on skin, a nose congestion;
  • candidiasis.

Application instruction of Klionum (Way and dosage)

Pill is taken orally, after food or in time, washing down with milk.

The attending physician has to appoint duration of treatment and a dosage. The maximum quantity of drug in days makes 2 grams.

The instruction at a trichomoniasis:

  • of 18 flyings – 0,5 g a day, for 2 receptions within 10 days or 0,8 g a day, for 2 inclusion in one week or 2 g once (the patient and his partner);
  • of 10 flyings – 0,5 g a day for 2 receptions, 10 days;
  • from 5 to 10 years – 0,25-0,35 in days;
  • from 2 to 5 years – 0,25 g a day.

At a lambliasis:

  • of 18 flyings – 1 grams, for 2 receptions, 5-7 days;
  • of 8 flyings – 0,5 g, for 2 receptions;
  • from 5 to 8 years – 0,375 g a day;
  • of 3 years – 0,25 g a day for 2 receptions, 5 days.

At serious violations in work baking or kidneys the daily dose should be reduced twice.

Overdose

There can be nausea, an ataxy, vomiting. Treatment – according to symptoms.

Interaction

It is not combined with ethanol.

Strengthens effect of anticoagulants and drugs of lithium.

Phenytoinum, phenobarbital and other inductors of enzymes of a microsomal oxidation of a liver reduce efficiency of drug.

Cimetidinum and streptocides, increase the level of concentration of metronidazole in a blood plasma.

Terms of sale

Existence of the recipe is required.

Storage conditions

In the dark cool place (from 15 to 25 degrees). Not to allow hit in hands to children.

Period of validity

5 years.

At pregnancy and a lactation

At pregnancy it is not applied the 1st trimester, with care in the 2 and 4. Do not appoint during feeding a breast.

About Klionum

About Klionum differ. Drug effectively helps some with fight against trichomoniasis and even candidiasis. Others complain of individual intolerance, a severe itch and sleeplessness and consider that high performance of means does not cost such victims.

Zdravzona

  • Klionum D 100 No. 10 of a tablet vaginalnyegedeon Richter
  • Klionum of 250 mg No. 20 tabletkigedeon Richter
  • Klionum of 500 mg solution for infusions of 100 ml

Drugstore of IFC

  • Klionum D tbl vaginas. 100 mg No. 10, Gedeon Richtervengriya
  • Klionum tbl 250 mg No. 20, Gedeon Richter/Gideon-Richter-RUS Zaorossiya
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Apteka24

  • Klion-D 100Gedeon Richter (Hungary)

Paniapteka

  • Klionum D tab. of levers. No. 10

BIOSPHERE

  • Klion-D 100 mg No. 10 of the tab. of levers.
  • Klionum of 0,5% 100 ml solution for inf.fl.
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Section: Antifungal
PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use Klionum surely consult with the attending physician.