Ksanaks

Ксанакс Drug photo

The description is actual on 13.02.2015

  • Latin name: Xanax
  • ATH code: N05BA12
  • Active ingredient: Alprazolam (Alprazolam)
  • Producer: Pharmacia (Belgium), Pfayzer (USA).

Structure

In 1 tablet of an alprazolam of 0,25 mg or 0,5 mg.

Release form

Tablets

Pharmacological action

Anksiolitichesky, myorelaxation, anticonvulsant, sedative, somnolent.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

Ksanaks is anksiolititik. What is it? the Tranquilizer, a psychotropic drug which action is shown in elimination of neurotic manifestations: fear, concern and emotional pressure, alarm.

Ksanaks strengthens brake action of GAMK. Stimulates benzodiazepine receptors, reduces excitability of a subcortex.

Anksiolitichesky action is combined with the somnolent moderately expressed action. At the same time, the backfilling period is shortened, the number of awakenings decreases at night, dream time increases. The mechanism of somnolent action is connected with oppression of a reticular formation of a brain. Drug has the average duration of action.

Pharmacokinetics

After reception the gastrointestinal tract is quickly soaked up and in 2 hours its maximum concentration in blood is defined. For 80%. contacts blood proteins. It is metabolized in a liver. Semi-removal time — is removed 16 hours by kidneys.

Indications to use

  • panic frustration;
  • the uneasiness connected with a depression;
  • reactive depressions with suicide thoughts;
  • the neurosises accompanied with alarm, concern, deterioration in a dream;
  • psychopathies with alarm, tension, irritability;
  • abstinence syndrome at the patients having drug addiction and alcoholism;
  • senile tremor;
  • sleeplessness.

Contraindications

Side effects

Application instruction of Ksanaks (Way and dosage)

Pill is taken inside, irrespective of meal time. At first appoint the minimum doses (to 0,5 mg a day), afterwards at good tolerance increase a dose in the evening, and then in day.

Alarming states: appoint 0,5mg three times a day and increase 3 mg to the highest daily dose.

Panic frustration: 0,5 mg three times a day, a daily dose of 6 mg.

Treatment duration at a bad attack of fear — 3 months, at alarming frustration — 6 months, at panic frustration — 8 months.

More prolonged continuous use of drug is not recommended. The sharp termination of treatment can provoke an exacerbation of a disease therefore the dose is lowered by 0,5 mg every 3 day. Perhaps and slower decrease.

Overdose

It is shown by symptoms: drowsiness, confusion of consciousness, ataxy, decrease in reflexes, lump.

Treatment: the gastric lavage is carried out, sorbents are appointed, Norepinephrinum (is entered at hypotension), in the conditions of a hospital the antidote is applied flumazenit.

Interaction

Mutual strengthening of effect at purpose of neuroleptics, somnolent, antiepileptic HP, narcotic analgetics and ethanol. Drug strengthens action of hypotensive HP. Co-administration of Clozapine oppresses breath. Increases toxicity of the Zidovudine and reduces efficiency of the Levodopa.

Terms of sale

It is released according to the recipe.

Storage conditions

At a temperature not over 250C.

Period of validity

3 years.

Analogs

Alzolam, Zolomaks, Alprazolam, Ksanaks retard, Alproks, Kassadan, Heleks of WEDNESDAY, Neurol, Frontin, Heleks.

About Ksanaks

About Ksanaks in general positive. All note good effect at panic frustration, phobic and hypochiondrial states. Drug is capable to cumulation and has the prolonged effect. So, meet that year after end of a course patients well felt.

The withdrawal, despite a 3-month course of treatment drug was not. It is noted also that tablets of Ksanaks or Alprazolam Pfayzer are several times more effective and more qualitative than drugs of other producers. The disappointment and a regret causes in patients that the last years these drugs do not meet in the pharmaceutical market of Russia, analogs which by efficiency of action concede to branded are offered.

Section: For a nervous system
in more detail

Education: Graduated from Sverdlovsk medical school (1968 - 1971) as "Paramedic". Graduated from the Donetsk medical institute (1975 - 1981) as "An epidemiologist, a hygienist". Passed postgraduate study in the Central scientific research institute of epidemiology Moscow (1986 - 1989). An academic degree – the candidate of medical sciences (degree is awarded in 1989, protection – the Central scientific research institute of epidemiology Moscow). Numerous advanced training courses are studied in epidemiology and infectious diseases.

Experience: Work as the manager of department of disinfection and sterilization of 1981 - 1992. Work as the manager of department of especially dangerous infections of 1992 - 2010. Teaching activity at Medical institute 2010 - 2013.

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