Magvit

Магвит Drug photo

The description is actual on 27.07.2016

  • Latin name: Magvit
  • ATH code: A11EC
  • Active ingredient: Pyridoxine + Magnesium citrate (Pyridoxine + Magnesium citrate)
  • Producer: Minskinterkaps unitary enterprise (Republic of Belarus); GlaxoSmithKline Pharmaceuticals SA (Poland)

Structure

Magnesium citrate, a pyridoxine a hydrochloride, potato starch, magnesium stearate, lactose, pharmaceutical gelatin, glitserol, the water purified titanium dioxide, sodium lauryl sulfate, methylparahydroxybenzoate, dye quinolinic yellow.

Release form

Magvit — solid gelatinous capsules, yellow color in planimetric to the blister packaging in a cardboard pack No. 30.

Magvit B6 — tablets in a kishechnorastvorimy cover in a polypropylene bottle in a cardboard pack No. 50.

Pharmacological action

Filling shortage of magnesium.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

Properties of drug of Magvit are caused by the pharmacological properties which are its part of magnesium and B6 vitamin (a pyridoxine a hydrochloride). The microelement Magnesium takes active part in synthesis of nucleic acids and protein, in DNA replication and RNA, transfer and storage of energy, is a cofactor of various enzymatic reactions; is responsible for balance of intracellular potassium. The lack of magnesium is shown by a tremor, muscular weakness, a tetany, irritability, increase of reflex irritability, frustration of a dream, diarrhea, disturbances of a cordial rhythm.

Pyridoxine the hydrochloride takes part in synthesis of neuromediators and protein metabolism, normalizes a lipometabolism at atherosclerosis, is a part of a set of the enzymes participating in process of decarboxylation of amino acids improves transportation through a membrane of cells of amino acids. Participates in a metabolism of methionine, tryptophane, cysteine, glutaminic acid, it is necessary for activation of phosphorylase, production of serotonin, neuromediators, folic acid, glycine, porphyrines, piperidic acid, unsaturated fatty acids.

These two active ingredients supplement and strengthen pharmacological action of each other.

Pharmacokinetics

Magnesium is poorly soaked up in a gastrointestinal tract (50% of the accepted dose), distributed in an organism mainly in intracellular space. It is allocated from an organism with urine.

Absorption of a pyridoxine of a hydrochloride happens mainly in a small intestine, is phosphorylated with participation of pyridoxal kinases and ATP. The metabolism of coenzymes is carried out in fabrics by oxidation. A key product of disintegration is piridoksilovy acid which is removed through kidneys.

Indications to use

Treatment of conditions of deficit of magnesium as a part of therapy of arrhythmia, hypertensia, stenocardia, congestive insufficiency, a myocardial infarction, the progressing atherosclerosis and osteoporosis.

Prevention of deficit of magnesium at frustration of a dream, chronic fatigue, irritability, a depression, intensive loadings, a headache, stressful situations, muscle pains, at long purpose of diuretics to patients with a hyperglycemia and a diabetes mellitus.

Contraindications

High sensitivity to drug, a renal failure, children's age, the lactation period, a fenilketonuriya. Magvit at pregnancy to accept only according to vital indications.

Side effects

Disorders of a gastrointestinal tract, allergic reactions.

Magvit, the application instruction (A way and a dosage)

To take a pill of Magvit only after consultation with the doctor. The dosage for adults makes 2 capsules during food, washing down with water 2-3 times a day for 1-2 months. At achievement in blood of normal concentration of magnesium to stop administration of drug.

Overdose

The expressed hypotonia, nausea, delay of reflexes, vomiting, respiratory depression, anury, coma, cardiac standstill.

Interaction

Joint reception with HP, calcigerous and phosphates considerably reduces absorption of magnesium in a gastrointestinal tract. Magnesium reduces tetracycline absorption, digestion of iron, reduces efficiency of peroral trombotichesky means.

Aminoglycosides, mineralokortikoida, diuretics, CycloserinumCisplatinum increase release of magnesium with urine.

The pyridoxine reduces protivoparkinsonichesky action of a levodopa. At joint reception with oral contraceptives, Cycloserinum, an isoniazid, concentration of a pyridoxine in blood decreases. At long purpose of Penicillaminum high risk of development of deficit of a pyridoxine.

Terms of sale

Nonprescription sale.

Storage conditions

At a temperature up to 25 °C.

Period of validity

24 months.

Magvit's analogs

Coincidence on the ATH code of the 4th level:

Magnefar of B6, Magnikum, Magne-B6 anti-stress, Beresh plus, Magnerot, Magnesium Plus, Magnelis B6 and others.

About Magvita

According to doctors of Magvit is an effective remedy at conditions of primary and secondary deficit of magnesium, including at decrease in level of the magnesium caused by reception in HP and inborn deficit of magnesium.

BIOSPHERE

  • Magvit No. 30 kaps.
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Section: Vitamins
in more detail

Education: Graduated from Sverdlovsk medical school (1968 - 1971) as "Paramedic". Graduated from the Donetsk medical institute (1975 - 1981) as "An epidemiologist, a hygienist". Passed postgraduate study in the Central scientific research institute of epidemiology Moscow (1986 - 1989). An academic degree – the candidate of medical sciences (degree is awarded in 1989, protection – the Central scientific research institute of epidemiology Moscow). Numerous advanced training courses are studied in epidemiology and infectious diseases.

Experience: Work as the manager of department of disinfection and sterilization of 1981 - 1992. Work as the manager of department of especially dangerous infections of 1992 - 2010. Teaching activity at Medical institute 2010 - 2013.

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