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Magnesium citrate, a pyridoxine a hydrochloride, potato starch, magnesium stearate, lactose, pharmaceutical gelatin, glitserol, the water purified titanium dioxide, sodium lauryl sulfate, methylparahydroxybenzoate, dye quinolinic yellow.
Magvit — solid gelatinous capsules, yellow color in planimetric to the blister packaging in a cardboard pack No. 30.
Magvit B6 — tablets in a kishechnorastvorimy cover in a polypropylene bottle in a cardboard pack No. 50.
Filling shortage of magnesium.
Pharmacodynamics and pharmacokinetics
Properties of drug of Magvit are caused by the pharmacological properties which are its part of magnesium and B6 vitamin (a pyridoxine a hydrochloride). The microelement Magnesium takes active part in synthesis of nucleic acids and protein, in DNA replication and RNA, transfer and storage of energy, is a cofactor of various enzymatic reactions; is responsible for balance of intracellular potassium. The lack of magnesium is shown by a tremor, muscular weakness, a tetany, irritability, increase of reflex irritability, frustration of a dream, diarrhea, disturbances of a cordial rhythm.
Pyridoxine the hydrochloride takes part in synthesis of neuromediators and protein metabolism, normalizes a lipometabolism at atherosclerosis, is a part of a set of the enzymes participating in process of decarboxylation of amino acids improves transportation through a membrane of cells of amino acids. Participates in a metabolism of methionine, tryptophane, cysteine, glutaminic acid, it is necessary for activation of phosphorylase, production of serotonin, neuromediators, folic acid, glycine, porphyrines, piperidic acid, unsaturated fatty acids.
These two active ingredients supplement and strengthen pharmacological action of each other.
Magnesium is poorly soaked up in a gastrointestinal tract (50% of the accepted dose), distributed in an organism mainly in intracellular space. It is allocated from an organism with urine.
Absorption of a pyridoxine of a hydrochloride happens mainly in a small intestine, is phosphorylated with participation of pyridoxal kinases and ATP. The metabolism of coenzymes is carried out in fabrics by oxidation. A key product of disintegration is piridoksilovy acid which is removed through kidneys.
Indications to use
Treatment of conditions of deficit of magnesium as a part of therapy of arrhythmia, hypertensia, stenocardia, congestive insufficiency, a myocardial infarction, the progressing atherosclerosis and osteoporosis.
Prevention of deficit of magnesium at frustration of a dream, chronic fatigue, irritability, a depression, intensive loadings, a headache, stressful situations, muscle pains, at long purpose of diuretics to patients with a hyperglycemia and a diabetes mellitus.
Disorders of a gastrointestinal tract, allergic reactions.
Magvit, the application instruction (A way and a dosage)
To take a pill of Magvit only after consultation with the doctor. The dosage for adults makes 2 capsules during food, washing down with water 2-3 times a day for 1-2 months. At achievement in blood of normal concentration of magnesium to stop administration of drug.
Joint reception with HP, calcigerous and phosphates considerably reduces absorption of magnesium in a gastrointestinal tract. Magnesium reduces tetracycline absorption, digestion of iron, reduces efficiency of peroral trombotichesky means.
Aminoglycosides, mineralokortikoida, diuretics, Cycloserinum, Cisplatinum increase release of magnesium with urine.
The pyridoxine reduces protivoparkinsonichesky action of a levodopa. At joint reception with oral contraceptives, Cycloserinum, an isoniazid, concentration of a pyridoxine in blood decreases. At long purpose of Penicillaminum high risk of development of deficit of a pyridoxine.
Terms of sale
At a temperature up to 25 °C.
Period of validity
According to doctors of Magvit is an effective remedy at conditions of primary and secondary deficit of magnesium, including at decrease in level of the magnesium caused by reception in HP and inborn deficit of magnesium.
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