Potassium permanganate

Марганцовка Drug photo

The description is actual on 14.03.2016

  • Latin name: Potassium permanganate
  • ATH code: D08AX06
  • Active ingredient: Potassium permanganate (Potassium permanganate)
  • Producer: Tatkhimfarmpreparata, Yaroslavl farmfabrika, PFK Updating, Tula pharmaceutical factory, Usolye-Siberian HFZ (Russia)

Structure

Active agent in pure form.

Release form

Powder for preparation of solution for topical and external use. It is packaged in well corked container (cans, banks or — if it is intended for individual use — in small packaging).

Pharmacological action

Deodorizing, antiseptic.

Pharmacodynamics and pharmacokinetics

Permanganate Potassium — what is it?

Permanganate potassium or potassium permanganate is a potassium permanganate. Drug has an appearance of small powder (crystals) of red or dark-violet color with metal gloss. In water substance is dissolved in the ratio 1:18, weak aqueous solution pinkish, strong solution is painted in dark-violet color.

Pharmacodynamics

Antiseptic agent. At potassium permanganate contact (permanganate potassium) with organic matters elemental oxygen is formed.

Oxide which is formed at drug recovery forms complex connections with proteins — albuminates. At the expense of what permanganate potassium in small concentration possesses the knitting properties, and in strong solutions shows the cauterizing, irritating and tanning action.

Shows the deodorizing properties. It is effective at treatment of ulcers and burns.

Potassium permanganate possesses ability to neutralize separate poisons, and this its property is quite often used in situations when it is necessary to make a gastric lavage at food toxicoinfections and poisoning with unknown substances.

Pharmacokinetics

At hit it is inside soaked up, can become the reason of development of a methemoglobinemia (gematotoksichesky action).

Indications to use of Permanganate potassium: for what potassium permanganate is necessary?

As an antiseptic agent aqueous solutions with concentration about 0,1% are applied.

Means is used for processing of the burned body parts, for washing of ulcers and contaminated wounds, for rinsing of a stomatopharynx and a throat at infectious and inflammatory diseases of a mucous oral cavity and stomatopharynx (including at quinsy), and also for processing of skin at hit of phenyl amine (aniline) on it and eyes in case of their defeat by poisonous insects.

As a vomitive potassium permanganate is accepted inside at poisoning with alkaloids (for example, aconitine, morphine or nicotine), quinine, phosphorus, cyanhydric acid. Optimum concentration of solution of potassium permanganate at poisoning — 0,02-1%.

With addition of permanganate potassium prepare solution for bathing of the newborn.

Whether it is possible to be washed away by Potassium permanganate solution?

Syringing by potassium permanganate in gynecology sometimes is applied at inflammatory processes and the milkwoman.

At the milkwoman and a number of urological diseases recommend to men a podmyvaniye with potassium permanganate.

Syringings at the milkwoman carry out by solution of weak-pink color (concentration not higher than 0,1%). It is necessary to remember that such means as potassium permanganate gives short-term antimicrobic effect (the pathogenic flora is destroyed only for the period of carrying out procedure) therefore it is necessary to use it only as addition to the main treatment.

Crystals of drug have property to be dissolved not at once. In this regard, not to provoke a burn mucous generative organs, for podmyvaniya / syringings prepare solution as follows: in the beginning in separate ware do concentrated (bright crimson color) solution, and then gradually pour in it in boiled water.

Potassium permanganate at a diarrhea

Aqueous solution of permanganate potassium in traditional medicine is quite often applied to treatment of a diarrhea. At diarrhea adults usually accept means inside, to children (including infantile age) more often do an enema with potassium permanganate.

At a diarrhea in a glass of water dissolve several kristallik of potassium permanganate, and then pour in the received solution in other capacity with water. A single dose for the adult — 200 ml, for the child — 100 ml. In certain cases for the termination of diarrhea it is enough to drink 1 single dose of medicine.

Potassium permanganate is a salt of manganic acid. Its efficiency at vomiting and a diarrhea is caused by the high oxidizing ability permanganate ion which provides antiseptic action of means.

Potassium permanganate at hemorrhoids

At hemorrhoids of a tray, lotion and a podmyvaniye with potassium permanganate promote reduction of hypostasis, burning and painful feelings in a rectum, thereby significantly facilitating a condition of the patient.

For preparation of a tray at hemorrhoids it is necessary to part 1,5 tablespoons of dry powder of potassium permanganate in 10 l of warm water. The specified proportions are relative.

First of all it is recommended to be guided by color of ready solution: liquid has to be gentle-pink, not bright. Too strong solution can provoke a corrosive burn of already inflamed and sensitive skin.

Procedure duration — 15 minutes. It is necessary to repeat it for achievement of lasting effect 2-3 times a day. Treatment is continued until improvement becomes noticeable.

If there is no opportunity to make a tray, the same result can be received by means of lotions (applications) with potassium permanganate.

Solution can be also used for regular hygiene of an anus. Treatment usually lasts about 1 week.

Contraindications

Hypersensitivity.

Side effects

Hypersensitivity reactions. In case of use of too strong solution the irritation and burns are possible.

Potassium permanganate: application instruction

According to the application instruction, means is applied outwardly, in the form of aqueous solutions of various concentration:

  • 0,02-1% — for a gastric lavage at poisoning, syringings and a podmyvaniye;
  • 0,01-1% — for rinsing of a throat and an oral cavity;
  • 0,1-05% solution — for processing of wounds;
  • 2-5% — for greasing of burn and ulcer surfaces.

Use of strong solutions of Potassium permanganate

Five-percent solution of permanganate potassium is considered especially concentrated therefore it cannot be used under no circumstances for internal consumption and processing of mucous: means is applied only in extreme cases and only outwardly.

Some specialists recommend to use it for treatment of a fungal infection of skin and onychomycoses, however most of mycologists prefer to appoint special antifungal drugs as they, in their opinion, are safer and effective.

There is also an opinion that 5% solution is effective at stings of poisonous insects (for example, tarantulas or scorpions) and venomous snakes. In this case it is used for washing of the struck place, however the similar measure can be regarded only as first aid to the victim, and does not cancel need of the address to the doctor and immediate (if it is necessary) hospitalization.

In traditional medicine of a lotion with the concentrated cold (!) solution of potassium permanganate sometimes are used for treatment of thermal burns. It is considered also that regular processing of decubituses of body parts, dangerous from the point of view of emergence, by strong solution of permanganate potassium, helps to prevent dystrophic or ulcer and necrotic change of fabrics.

Safety and efficiency of such treatment, however, should be discussed with the attending physician without fail.

Five-percent solution is used also for treatment of generalized damages of skin, for example, of a pyoderma.

The bathtub from spots with permanganate potassium promotes acceleration of drying of elements of rash and falling away of crusts. Procedure is repeated daily before disappearance of displays of a disease. Influence duration — no more than 15 minutes. After a bathroom it is recommended to rinse skin with cool water.

Strong solution can be used from back spots, and also for cauterization of callosities and warts. Means in the specified cases is put pointwise.

How to dissolve Potassium permanganate at chicken pox?

At chicken pox potassium permanganate is dissolved so that not too strong solution turned out. It means that liquid has to be light pink color.

Rules of cultivation following: in the beginning several grains of potassium permanganate dissolve approximately in 500 ml of warm water, and then pour the received solution in other capacity and bring water volume to necessary.

Wipe with a replaceable cotton plug in solution places of rashes. When rashes descend, for acceleration of process of drying of crusts it is possible to take baths with not strong solution of permanganate potassium.

How to make 5% Potassium permanganate solution?

For preparation of 5% solution of 5 grams of drug dissolve in 100 ml of water. Not to be mistaken with a dosage, it is necessary to use kitchen scales.

If there are no scales, in calculations of the necessary amount of potassium permanganate make a start from the fact that 1 h to its spoon holds 6 grams. Thus, for receiving 5% solution, it is necessary to add this amount of potassium permanganate to 120 ml of water.

If in a drugstore the 3-gram bottle with potassium permanganate was bought, for receiving solution of the necessary concentration potassium permanganate should be connected from 70 ml of water.

When all crystals are dissolved in water, filter ready solution through the gauze put in several layers.

How to part for bathing the newborn Margantsovka?

As skin of babies very gentle and sensitive, for bathing light pink, not strong solution for bathing has to be used.

Recommendations how to make weak solution of potassium permanganate the following: in transparent glasswares pour warm water and add small (on a knife tip) amount of potassium permanganate.

Having convinced that all kristallik were dissolved, solution is poured in other capacity and add water up to the necessary volume.

Overdose

Symptoms of overdose are shown by sharp pain in an oral cavity, on the course of a gullet and in a stomach, diarrhea, vomiting. Mucous stomatopharynxes swells (throat hypostasis is possible), changes color on dark brown or violet.

Besides, at the victim burn shock and mechanical asphyxia develop; there are spasms, motive excitement, the phenomena of parkinsonism, a nephropathy, hemorrhagic colitis, a hepatopathy.

At the lowered acidity of a stomach the methemoglobinemia with short wind and the expressed cyanosis can develop.

For the child the dose equal of 3 g is deadly. For the adult the size of a lethal dose fluctuates ranging from 0,3 to 0,5 g/kg.

Treatment: in/in introduction of 5% of solution of Ascorbic acid (30 ml), introduction of the Pyridoxine in oil of 5% (3 ml) and Cyanocobalamine (to 1 g), and also 1% of solution methylene blue (50 ml).

Interaction

Permanganate potassium is chemically incompatible with a number of organic matters (including tannin, sugar, coal).

Blows up when processing by the concentrated H2SO4 (sulphuric acid).

Even at insignificant (to room temperature) heating actively interacts with the majority of reducers (for example, with glycerin) and the easily oxidized substances. Reaction is followed by self-heating that in some cases causes self-igniting mixes and can lead to explosion.

It is very dangerous to pound crystals of permanganate potassium with powders of active metals and nonmetals (aluminum, sulfur, calcium, phosphorus, magnesium, etc.) as similar actions quite often are followed by explosion.

Terms of sale

Potassium permanganate in Russia is included in the IV list of precursors of PKKN, in Ukraine from 14.06.2013 is also recognized as a precursor and entered in the list of narcotic substances.

In the Russian drugstores, it agrees to Minzdavsotsrazvitiya approved by the Order of the Russian Federation No. 578 of 13.09.2005 "To the list of the HP which are released without recipe of the doctor" which worked till 16.10.2011, means has to be released without recipe, but no more than 2 packagings per customer.

The recipe on Latin (sample): Rp: Sol. Kalii permanganatis of 5% 10 ml DS. For processing of edges of a wound.

Storage conditions

Powder has to be stored in the dark place in well corked container.

Period of validity

It is not limited. No more than 3-4 days are recommended to store aqueous solutions.

Special instructions

Potassium permanganate — what is it?

In Wikipedia it is specified that potassium permanganate which in life more often is called potassium permanganate is potassium salt of manganic acid — strong inorganic acid which has a formula HMnO4.

As potassium permanganate looks, it is known to all — everyone at least once in life saw crystals, dark-violet with metal gloss.

Properties and use of Potassium permanganate in medicine

Permanganate potassium is a strong oxidizer and, therefore, possesses the expressed antiseptic (antimicrobic) action.

Effects of means are explained by the fact that in aqueous solution in the presence of easily oxidized elements from permanganate potassium oxygen which shows properties of very powerful antiseptic agent begins to be chipped off actively gaseous type.

In strong solutions potassium permanganate renders expressed cauterizing and an irritant action.

That it is possible to make of Potassium permanganate: alternative routes of administration

In addition to medicine, means is used:

  • for determination of permanganate oxidability at an assessment of quality of water by Kubel's method;
  • for washing of a laboratory glassware (alkaline solution of potassium permanganate well cleans the remains of fat and other organic matters);
  • in pyrotechnics (as a strong oxidizer);
  • for toning of photos (solutions with concentration of potassium permanganate of 3 g/l);
  • in space liquid and rocket engines (as the hydrogen peroxide decomposition catalyst);
  • for etching of a tree;
  • for removal of tattoos (however such way does not allow to clean completely a tattoo and leaves scars on a body);
  • for receiving carboxylic acids from paraffin;
  • for whitening of fabrics.

It is possible to find video "Potassium Permanganate and Gasoline" in which potassium permanganate is recommended to add to a car gasoline tank for fuel enrichment by oxygen in the Internet.

Chemical properties

Potassium permanganate formula — KMnO4. Molar weight — 158,03 g/mol. Substance has an appearance of dark-violet crystals, does not form crystalline hydrates, is characterized by moderate solubility in water (solubility increases at water temperature increase), not hydrolyzed, in solutions decays slowly.

Strong oxidizer at agglomeration and in solution. Reacts with typical reducers (hydrogen, ethanol, etc.). Strong solutions have intensive violet coloring, weak — are painted in pink color.

Oxidizing ability permanganate ion weakens in process of reduction of acidity of solution. In the alkaline environment under the influence of reducers it is recovered to manganate ion; MnO4 in the alkalescent, neutral and subacidic environment passes into manganese dioxide.

In the acid environment permanganate ion is transformed in akvakation.

The factor of equivalence of permanganate fэкв(KMnO4) potassium depending on acidity of the environment makes 1/5, ⅓ and 1.

The diluted aqueous solution of permanganate potassium is unstable and release of oxygen decays with formation of a deposit of manganese dioxide (flakes of brown color) also. Decomposition accelerates under the influence of sunshine.

Especially quickly potassium permanganate solution in the presence of reducers spoils.

The acidified solution becomes colourless under the influence of solution of oxalic acid. It is also used when carrying out the titrimetric analysis when determining hydrogen peroxide, salts of iron (II), oxalates.

Hydrocarbon does not decolour potassium permanganate solution (acidified). Benzene does not decolour potassium permanganate solution. Leads a transmission through the acidified hydrogen sulfide KMnO4 solution to decolorization.

Ethylene decolours potassium permanganate solution at a transmission through it (in process of oxidation of ethylene in ethylene glycol).

Ethylene oxidation reaction potassium permanganate looks so:
реакция окисления

During this reaction decolorization of violet coloring of aqueous solution of permanganate potassium therefore it is used as high-quality reaction to alkenes is noted.

Weak solution of KMnO4 in the neutral and alkaline environment provokes oxidation of alkenes to diols (reaction of a hydroxylation of alkenes or Wagner's reaction).

Acetylene oxidation by permanganate potassium in the alkalescent environment proceeds with formation of potassium oxalate. Reaction of acetylene with KMnO4 is described by the equation: 3C2H2 + 8KMnO4 = 3K2C2O4 + 2H2O + 8MnO2 + 2KOH

In the acid environment acetylene is oxidized to carbon dioxide: C2H2 + 2KMnO4 + 3H2SO4 = 2CO2 + 2MnSO4 + 4H2O + K2SO4

Oxidation of aldehydes which are strong reducers proceeds when heating and is described by a formula: 3CH3CHO + 2KMnO4 = CH3COOH + 2CH3COOK + 2MnO2 + H2O

Alcohol oxidation by potassium permanganate in the presence of concentrated sulphuric acid and when heating by a languid flame begins with solution decolorization. As a result of this reaction flakes of manganese oxide (IV) of brown color drop out. At surplus of H2SO4 solution becomes colourless, the smell of acetic aldehyde is felt.

Oxidation by permanganate potassium in the alkaline environment allows to receive 3 nitrotoluene au nitrobenzoic acid.

Decomposition of potassium permanganate when heating is one of ways of receiving oxygen. For this purpose it is necessary to fill in a test tube with a colonic tube crystals of KMnO4 and then to heat a test tube.

At the same time the emitted oxygen on a tube will come to a flask and to gradually fill it (O2 heavier than air therefore does not leave a flask). If to place the smoldering splinter in a flask, it will flash.

The equation of decomposition reaction of potassium permanganate looks so: 2 KMnO4 = K2MnO4 + MnO2 + O2 ↑

Purification of moonshine with Potassium permanganate and soda

At moonshiners the method of purification of moonshine by means of potassium permanganate, baking soda and alkali enjoys wide popularity (for example, the caustic soda). Potassium permanganate cleans fusel oils, drinking soda neutralizes acetic acids, alkali — other harmful impurity.

In the absence of alkali it is possible to be limited to use only of potassium permanganate and soda.

Sequence of actions:

  • Potassium permanganate is dissolved in water at the rate of 1,5 g on 1 l of a product.
  • Soda is dissolved in water. For cleaning of 10 l of moonshine it is necessary to prepare solution from 100 g of soda and 100 ml of water.
  • To pour in moonshine in the beginning in soda solution, to mix, and then potassium permanganate solution.
  • To insist within half an hour.
  • To dissolve the caustic soda (or other alkali) with water in equal proportions at the rate of 2 g on 1 l of moonshine (alkali is filled in with water, but do not pour out in water — it is important!).
  • Moonshine is covered and upheld in the dark place during 12-14 h, and then filtered through coal or cotton wool.

Use of Potassium permanganate in gardening

Gardeners and gardeners know about useful properties of potassium permanganate and therefore everywhere use potassium permanganate for plants.

Use on a kitchen garden is reasonable when it is necessary to pickle seeds before landing: such processing allows to destroy the causative agents of diseases wintering on seeds.

To prepare solution of the necessary concentration in 100 ml of water dissolve 0,5 g of potassium permanganate. Seeds place in the received liquid for 20 minutes, and then dry.

Processing of potatoes before landing by potassium permanganate allows to protect tubers from disease-producing fungi and a provolochnik. For soaking of tubers solution of dark pink color is used.

For processing of onions before landing use pink solution. Cloves place in it so that liquid covered them, and leave for 8-12 hours.

Means with such structure well is suitable for processing of strawberry in the spring: 1 glasses of ashes, 1-2 l of boiled water (ashes are filled in with the boiling water and allow it to cool down), 2 g of potassium permanganate, 2 g of powder of boric acid, 1 tablespoon of iodine. Mix is filtered, poured out in a bucket and added water, used for spraying.

Solution works both as fertilizer, and as means from wreckers.

Solution of potassium permanganate it is possible to spill soil for seedling, to wash boxes, pots and glasses before landing of greens or seedling, to process hotbeds and greenhouses for prevention of diseases of plants.

For processing of soils, for seedling, watering of strawberry and bushes (a gooseberry, raspberry, currant) use the solution prepared in proportions of 3 g of potassium permanganate on 10 l of water in the early spring. In particular it is good to use such means on sandy soils.

Nevertheless, to you it is not necessary to be fond of potassium permanganate for processing of the earth and watering of flowers nevertheless — the excess content of manganese in the soil can adversely affect development of plants.

Spraying of wild strawberry the solution prepared in proportions of 2 h a spoon of potassium permanganate on 10 l of water rescues wild strawberry from blueberry blossom bligth. Processing of berries should be carried out after blossoming.

Whether it is possible to water seedling with potassium permanganate? Potassium permanganate solution is usually used for disinfection of the soil in the boxes and glasses adapted for seedling, and also on beds. The seedling in glasses needs to be watered with warm pink solution of times in ten days (at will alternating to watering by cindery leach).

Before disembarkation in soil of any seeds the earth in a box is watered with solution for which preparation 3-5 g of potassium permanganate dissolve in 10 l of water.

Interests many gardeners whether it is possible to water tomatoes with potassium permanganate. Experienced specialists claim that it is even necessary as such processing prevents many blights.

Whether it is possible to water flowers with potassium permanganate? It is possible, but not too being zealous not to do much harm. The advantage of such watering by solution of potassium permanganate is huge.

First, the plant receives additional manganese and potassium. Secondly, acidity of the soil increases that favors to growth of some plants. Thirdly, soil is disinfected.

Solution for flowers has to be light pink color. For its preparation several drops of strong solution of potassium permanganate are enough to drip in a glass of water.

How to wash Potassium permanganate from hands?

To wash away the spots left potassium permanganate from hands, it is possible to use a lemon segment, alcohol or the vinegar and peroxide of hydrogen mixed in equal proportions of 5-9%.

The people advising than to wash potassium permanganate from skin, also note efficiency of universal detergent which is prepared from 100 g of soap (children's or economic, rubbed on a small grater), 100 ml of hot water, baking soda (2-3 tablespoons) and 2-3 drops of essential oil.

Potassium permanganate plus sugar: to make fire make-shifts

To make fire without matches, it is necessary to take a stick, a flat plate, potassium permanganate and sugar. A stick strongly rub potassium permanganate with sugar. As a result of a chemical change mix self-ignites.

Precautionary measures

It is not necessary to dissolve and store potassium permanganate in metal tanks as potassium permanganate will enter with them interaction and will lose part of medicinal properties. To optimum use glasswares for preparation of aqueous solutions.

If potassium permanganate provoked a burn — what to do?

At a burn of an oral cavity, a gullet and stomach strong solution of permanganate potassium the victim should wash out immediately a stomach, to give it Absorbent carbon and weak solution of peroxide of hydrogen with vinegar (a half-glass of peroxide and 1 glass of vinegar on 2 l of water).

What it is possible to replace potassium permanganate with?

Analogs of potassium permanganate: Ammonia + glitserol + ethanol, Aseptolin, Anmarin, Baktoderm, Vitaon, Dermatolo-degtyarny linimentum, Dioksizol, Zelenka, Caleflonum, Katapol, Katatsel, Naftalannaya ointment, alcohol, Protol, hydrogen Peroxide, Tambukan dirt, Formidronum, Formagel, Elekasol, Etol of 96%, Zinc and salicylic paste, Chaga.

Section: Antiseptic agents
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