Medical axon

Медаксон Drug photo

The description is actual on 22.01.2016

  • Latin name: Medaxone
  • ATH code: J01DD04
  • Active ingredient: Tseftriakson (Ceftriaxone)
  • Producer: Medochemie Ltd., Cyprus, Europe

Structure

Tseftriaksona sodium salt

Release form

Powder of white color for preparation of solution for intramuscular and intravenous use in glass bottles on 0,5 g and 1,0 g in cardboard packaging.

Pharmacological action

Bactericidal.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

Antibiotic of a tsefalosporinovy row for parenteral use. The mechanism of action is based on oppression of process of synthesis of a cellular membrane. Drug with bactericidal effect of rather large number of microorganisms, is steady concerning the enzymes produced by bacteria (penicillinases, tsefalosporinaza).

Pharmacokinetics

Tseftriakson at parenteral administration is quickly soaked up and gets on liquid Wednesday and body tissues. The elimination half-life on average — eight hours, at elderly patients — practically doubles. Bioavailability at introduction in oil — 100%. Bactericidal effect of drug to sensitive to it microorganisms remains for one days. Linkng with proteins — 85-95%. Tseftriakson in 50-60% is allocated with urine in not changed form, and 40-50% with bile.

Indications to use

  • the infectious diseases caused by the microflora sensitive to a tseftriakson (to an infection of LOR-bodies, respiratory tracts, joints, bones, skin, an abdominal cavity, urinary tract, kidneys, connecting fabric, urogenital infections, meningitis, sepsis);
  • infectious diseases at patients with the lowered immunity;
  • In the postoperative period for the purpose of prevention of infections.

Contraindications

Hypersensitivity to drug, a renal liver failure, diseases of a gastrointestinal tract and bleeding in the anamnesis (enteritis, ulcer colitis), a lactation or pregnancy.

Side effects

  • local allergic reactions: fever, urticaria, rash, an itch, is more rare — a bronchospasm, a serum disease, a polymorphic, exudative erythema, an eosinophilia, an acute anaphylaxis;
  • nausea, vomiting, meteorism, diarrhea or lock, pains in a stomach, stomatitis, taste disturbance, a coloenteritis, dysfunction, dysbacteriosis;
  • granulocytopenia, leukopenia, neutropenia, hypocoagulation, hemolitic anemia;
  • oliguria, hamaturia, azotemia, anury, increase of indicators of urea in blood;
  • morbidity on the vein course, phlebitis, a headache, nasal bleedings, dizziness, candidiasis.

Medical axon, application instruction (Way and dosage)

The drug is administered in oil and in / century. The average daily dose for adults makes 1-2 g once a day. Pricks are carried out by Medakson in 24 hours. In certain cases (severe forms of a disease, moderately sensitive microorganisms) the daily dose increases to 4 g.

To children to 12-year age the daily dose is calculated on body weight at the rate of 20-75 mg/kg; weighing more than 50 kg drug is appointed in doses for adults. Newborns are not recommended to exceed a dose of 50 mg/kg. The course of treatment depends on a type of a pathogenic microorganism, the course of a disease and can proceed from 4 to 14 days.

For prevention of infections after the operational period the drug is administered prior to operation in one hour once in a dose of 1-2 g.

Overdose

Strengthening of manifestation of side effects is possible.

Interaction

Due to the incompatibility of a tseftriakson and aminoglycosides it is necessary to appoint them separately, without exceeding the recommended doses.

Tseftriakson is incompatible with ethanol.

Because of chemical incompatibility it is impossible to mix drug in one syringe or an infusional bottle with other antibiotic.

Terms of sale

According to the recipe.

Storage conditions

At a temperature not above 25 °C.

Period of validity

2 years.

Medakson's analogs

On active ingredient treat analogs of drug: Axon, Azaran, Biotrakson, Lendatsin, Megion, Betasporin, Longatsef, Movigip, Lifakson, Rotsefin, Steritsef, Oframaks, Torotsef, Triakson, Tertsef, Hizon, Fortsef, Tsefatrin, Tsefogram, Tsefakson, Tseftriakson of sodium, Tseftriabol, Tsefson, Tseftriakson.

About Medakson

About drug favorable. Generally report about high performance of Medakson. Some patients complain of absence of due result. But, at the same time, they do not report whether they were carried out determination of sensitivity of microflora to drug, and this necessary condition of effective treatment by antibiotics.

Often ask whether drugs Medakson and Tseftriakson differ with something? These are absolutely identical drugs with similar active ingredient. A difference between them only in producers. Tseftriakson is issued in Ukraine, and Medakson is made in Europe.

Zdravzona

  • Medical axon powder for injections of 1 g No. 100medokemi of Ltd.
to show still

Apteka24

  • Medical axon powder for injections of 1 g No. 10medokhemi (Cyprus)

Paniapteka

  • Medical axon of a time. for infection. 1 g No. 10
Section: Antibiotics
in more detail

Education: Graduated from Sverdlovsk medical school (1968 - 1971) as "Paramedic". Graduated from the Donetsk medical institute (1975 - 1981) as "An epidemiologist, a hygienist". Passed postgraduate study in the Central scientific research institute of epidemiology Moscow (1986 - 1989). An academic degree – the candidate of medical sciences (degree is awarded in 1989, protection – the Central scientific research institute of epidemiology Moscow). Numerous advanced training courses are studied in epidemiology and infectious diseases.

Experience: Work as the manager of department of disinfection and sterilization of 1981 - 1992. Work as the manager of department of especially dangerous infections of 1992 - 2010. Teaching activity at Medical institute 2010 - 2013.

PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use Medakson surely consult with the attending physician.