Meksikor

Мексикор Drug photo

The description is actual on 12.08.2014

  • Latin name: Mexicor
  • ATH code: C01EB
  • Active ingredient: Etilmetilgidroksipiridina succinate (Ethylmethylhydroxypyridine succinate)
  • Producer: Ekofarminvest (Russia)

Structure

One capsule contains active agent: oxymethylethylpyridine succinate – 0, 1 g, and also excipients – succinic acid, milk sugar, potato starch and magnesium stearate.

Contains in ampoules of 2 ml succinate oxymethylethylpyridine – 100 mg, Trilonum of B and water for injections.

Release form

Medicine is let out in capsules on 0,1 g of active agent and ampoules on 2 ml which contain 50 mg/ml of the main component.

Pharmacological action

Meksikor possesses anti-hypoxemic, neuroprotective, nootropic, anksiolitichesky and antioxidant action.

Pharmacodynamics and pharmacokinetics

At treatment by this drug decreases displays of an oxidizing stress, free radical peroxide oxidation of lipids slows down and activity in antioxidant system of enzymes increases. Also the cellular power exchange improves, the power synthesizing functions of mitochondrions and compensatory activation of aerobic glycolysis are activated, extent of oppression of oxidizing processes decreases.

Besides, improvement of a brain metabolism and blood supply of a brain, microcirculation and reologicheskiy properties of blood, decrease in aggregation of thrombocytes and so on is noted.

Absorption of active agent in an organism comes from a gastrointestinal tract quickly and fully. The maximum concentration in a blood plasma is reached within an hour. At the same time drug is quickly enough distributed in fabrics and bodies.

Meksikor mainly in the form of a glyukuronokonjyugat, with urine is brought. The most active process is noted within the first 4 hours from the moment of administration of drug.

Indications to Meksikor's use

Drug in capsules is appointed in complex therapy at:

When appoint pricks Meksikor, indications to use can be similar, and also the acute period of a myocardial infarction.

Contraindications to use

  • acute disorders of activity of a liver and kidneys;
  • age of patients till 18 flyings as influence of drug is not established;
  • lactation, pregnancy;
  • sensitivity or intolerance of components of drug.

Side effects

At treatment by Meksikor the alimentary system can suffer that is followed by dyspepsia, dryness in a mouth, nausea, diarrhea. Usually these symptoms pass independently after drug withdrawal. Prolonged use of drug quite often leads to a meteorism.

Also problems with a dream and development of allergic reactions are not excluded.

Meksikor – the application instruction (A way and a dosage)

Medicine in ampoules is intended for intravenous drop or intramuscular administration. The course of treatment against the main medicamentous therapy of an acute myocardial infarction makes 14 days. To gain fast therapeutic effect in the first 5 days it is recommended to administer the drug intravenously, then to pass to intramuscular use.

It is necessary to carry out intravenous drop administration rather slowly using normal saline solution of sodium of chloride or 5% of solution of glucose volume. For example, 100-150 ml of solution should be entered within 30-90 minutes. It is also possible to put pricks, at the same time slow jet intravenous administration which is carried out by not less than 5 minutes is allowed.

As the application instruction of Meksikor in tablets reports, they need to be accepted in 8 hours on 3 times a day. The average one-time dosage makes 2-3 mg on weight kg, and daily – 6-9 mg on weight kg. An admissible maximum single dose of 0,25 g, and daily – 0,8 g. Usually capsules are appointed inside as a part of complex therapy.

For each disease the scheme of treatment and a necessary dosage of drug are defined by the doctor. At the same time the nosological form of a disease and individual sensitivity of the patient to medicine is considered. Duration of treatment by Meksikor can also be various, for example, at coronary heart disease and disturbances of cerebral circulation it makes 1,5-2 months.

Treatment by Meksikort needs to be finished gradually, lowering a daily dosage on 0,1 g.

Overdose

At overdose symptoms of sleeplessness, drowsiness, small increase of arterial pressure can be shown by this drug. Such cases does not demand special therapy as usually they pass independently.

If there is a substantial increase of arterial pressure, then tablets for its decrease, in addition with anti-anginal means are appointed.

Interaction

Reception of capsules and pricks Meksikor strengthen action protivoparkinsonichesky and anticonvulsants, and also anxiolytics of a benzodiazepine row. Besides, activity of anti-anginal drugs increases, the hypotensive effect of beta adrenoblockers, APF inhibitors and effect of antiarrhytmic drugs increases.

Terms of sale

Drug is released according to the recipe.

Storage conditions

The place of storage has to be dry, dark and protected from children, with a temperature up to 25 °C.

Period of validity

3 years.

Meksikor's analogs

It is necessary to notice that Meksikor and his analogs have identical active agent, and, therefore, and indications to use. Therefore treat them: Medomeks, Meksidant, Meksidol, Meksipridol.

Alcohol and Meksikor

As this medicine can be used for stopping of an alcoholic abstinence syndrome, the use of alcoholic drinks at treatment by Meksikor is not forbidden.

Zdravzona

  • Meksikor of 100 mg No. 20 of a kapsulymiraksbiofarm of closed joint stock company
  • Meksikor of 5% solution for injections of 2 ml No. 10 of an ampulyfirm Enzyme of Ltd company
  • Meksikor of 5% solution for injections of 5 ml No. 20 of an ampulyfirm Enzyme of Ltd company
  • Meksikor of 100 mg No. 30 of a kapsulymiraksbiofarm of closed joint stock company
  • Meksikor of 100 mg No. 60 of a kapsulymiraksbiofarm of closed joint stock company

Drugstore of IFC

  • Meksikor solution for in 5% 2 ml No. 10 *, Enzyme of Ltd company (г.Москва) Russia
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Section: Cardiological Cardiovascular
PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use Meksikor surely consult with the attending physician.