Мельдоний Drug photo

The description is actual on 04.07.2016

  • Latin name: Meldonium
  • ATH code: C01EB22
  • Active ingredient: Meldony (Meldonium)
  • Producer: Pharmstandard-Leksredstva, Ellara of Ltd company, Pharmstandard-UFAVITA, Biochemist, WHOM NPF, Farmamed of Ltd company (Russia)


In 1 ml of solutiona meldony dihydrate of 100 mg.

In 1 capsule — a meldoniya of 250 mg or 500 mg. Magnesium stearate, potato starch, silicon dioxide — as excipients.

Release form

  • capsules of 500 mg and 250 mg;
  • solution for injections.

Pharmacological action

Anti-ischemic, cardioprotective (improves a metabolism and power supply of a myocardium).

Pharmacodynamics and pharmacokinetics


Has cardioprotective effect, besides membranostabiliziruyushchy and immunotropny. Limits the speed of synthesis of a carnitine from a γ-butyrobetaine that attracts disturbance of transport of fatty acids in a mitochondrion. Under the influence of drug the level of a γ-butyrobetaine which strengthens formation of an oxide of nitrogen that attracts reduction of OPSS and a vazodilatation increases.

Meldony reduces ability of thrombocytes to aggregation and improves elasticity of membranes of erythrocytes. In the conditions of ischemia prevents disturbance of transport of ATP. At ischemic damage of a cardiac muscle slows down formation of a zone of a necrosis. At heart failure increases contractility of a myocardium and reduces quantity of attacks of stenocardia. It is effective at pathology of vessels of an eyeground. Increases working capacity. Eliminates disturbances of a nervous system at patients with an alcoholism.


It is well soaked up at intake. Bioavailability at such way of introduction of 78% and 100% at intravenous administration. Cmax is defined in blood by 1-2 h. It is metabolized with formation of two metabolites, they are removed by kidneys in not changed look.

Indications to use

Complex therapy:

  • the lowered working capacity;
  • dishormonal cardiomyopathy;
  • postoperative rehabilitation;
  • disturbances of cerebral circulation;
  • physical overstrain;
  • abstinence syndrome at an alcoholism.

Parabulbar introduction:

  • retinal apoplexy;
  • disturbance of blood circulation in a retina;
  • retina vein thrombosis;
  • retinopathies (diabetic and hypertensive).


Side effects

All side reactions meet seldom:

Meldony, application instruction (Way and dosage)

Capsules Meldony-Mick accept inside and in connection with a possibility of exciting effect they are recommended to be accepted in the morning. The dose and frequency rate of reception are selected individually.

At cardiological diseases — 500 mg-1000 of mg a day. Treatment lasts till 6 weeks.

At disturbances of cerebral circulation — 500 mg once a day, a course of 4-6 weeks.

At an abstinence syndrome — 500 mg 4 times a day.

At physical overworks — 250 mg 4 times a day, a course of 14 days.

Solution for injections

Usually the dose makes 0,5-1 g a day daily. The drug is administered on 10 ml 0,9% of NaCl solution.

Unstable stenocardia, state after the postponed myocardial infarction — enter in/in struyno 1–2 ampoules (500–1000 mg) 4 days in a row once a day. Stable stenocardia: dosage and frequency rate same introductions.

Parabulbarno is entered by 0,5 ml of solution.


Drug is a little toxic and cases of overdose do not meet or meet extremely seldom. Development of hypotension, tachycardia, headache, dizziness and the general weakness is theoretically possible. The symptomatic treatment is carried out.


Strengthens action of hypotensive, anti-anginal means, cardiac glycosides.

The combination to anti-anginal drugs, anticoagulants, antiarrhytmic means and diuretics is possible.

At simultaneous use with Nitroglycerine, alpha adrenoblockers, Nifedipine, peripheral vazodilatator there is a probability of emergence of tachycardia and arterial hypotension.

Not to apply along with the other drugs containing meldoniya.

Terms of sale

It is released according to the recipe of the doctor.

Storage conditions

Temperature of storage is up to 25 °C.

Period of validity

2 years.

Meldoniya's analogs

Mildronate, Idrinol, Midolat, Vazonat, Vazomag.

About Meldoniya

Purpose of this drug in complex treatment of cardiological pathology for 55,6% reduces quantity of attacks of stenocardia and daily need for nitroglycerine by 55,1%. Significantly improves reductions of a myocardium without influences on a cordial rhythm, limits fluctuations of the ABP. Drug malotoksichen also does not cause the expressed side reactions.

Judging by responses of patients, this means was appointed at an ischemic heart disease in a combination with anti-anginal and hypotensive drugs. Important that drug was appointed by the patient of the senior age groups and they well it transferred.

  • "... Me added a tablet Meldony at stenocardia, to other tablets. Noticed improvement in 3 weeks";
  • "… Accepted after a microinsult in capsules 2 times a day. Spent on drink one and a half months — the speech improved, cheerfulness appeared";
  • "… I accept courses three times a year. I can characterize it as vital for all. I have a stenocardia and is a little raised the ABP";
  • "… To the child year, very much I am tired. According to the recommendation of the neuropathologist I accept Meldony twice a day. I drink only week and already best of all I feel";
  • "… I was recommended by the neuropathologist (the diagnosis "chronic fatigue"). Pricked pricks. Excellent drug, quickly returns forces";
  • "… Noticed that Meldoniya's reception increases appetite a little, even recovered a little";
  • "… After 7 days of reception of this drug became the head is turned".


  • Meldony organic chemistry solution for injections 100mg/ml 5 ml No. 10 of an ampulyorganik of joint stock company
to show still
Section: Cardiological Cardiovascular
in more detail

Education: Graduated from Sverdlovsk medical school (1968 - 1971) as "Paramedic". Graduated from the Donetsk medical institute (1975 - 1981) as "An epidemiologist, a hygienist". Passed postgraduate study in the Central scientific research institute of epidemiology Moscow (1986 - 1989). An academic degree – the candidate of medical sciences (degree is awarded in 1989, protection – the Central scientific research institute of epidemiology Moscow). Numerous advanced training courses are studied in epidemiology and infectious diseases.

Experience: Work as the manager of department of disinfection and sterilization of 1981 - 1992. Work as the manager of department of especially dangerous infections of 1992 - 2010. Teaching activity at Medical institute 2010 - 2013.

PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use Meldony surely consult with the attending physician.