Миконазол Drug photo

The description is actual on 23.06.2016

  • Latin name: Miconazole
  • ATH code: D01AC02
  • Active ingredient: Miconazolum (Miconazole)
  • Producer: Elegant, India


Active component is a part of each form of drug: Miconazolum.

Additional components depend on the offered pharmacological form of Miconazolum.

Release form

Miconazolum in several dosage forms, for example, vaginal candles, cream, gel, tablets and solutions for internal use, spirit solution and liquid for external use is issued. At the same time candles are packaged in packagings on 8 or 15 pieces, cream is packed into tubas on 15 or 30 g, and gel – 40 g.

As for tablets, they are offered on 10 pieces in a pack, solution for intravenous administration is placed in ampoules on 5 pieces in packaging, spirtovy solution – in bottles from special brush 30 ml, and liquid for outside use of 30 g – in aerosol package.

Pharmacological action

The antifungal and antibacterial effect is characteristic of any form of drug.

Pharmacodynamics and pharmacokinetics

Miconazolum possesses ability to slow down cover ergosterol biosynthesis, and also plasma membranes of some mushrooms. Besides, change of lipidic structure and permeability of a cell wall is noted.

At the same time special sensitivity is shown by dermatomitseta and yeast. Most of all this drug is effective at treatment of diseases which cause mushrooms of Coccidioides immitis, Petriellidium boydii, Cryptococcus neoformans, Candida albicans, Paracoccidioides brasiliensis, Trichophyton, Malassezia furfur, Epidermophyton and some gram-positive bacteria.

When local applications of drug are used, in blood a small amount of metabolites appears. Getting into a liver, the main component is exposed to fast destruction. At system use removal happens to the help of kidneys. Drug difficult breaks gistogematichesky barriers, practically does not get into cerebrospinal fluid.

Indications to use

The main indications to use of this drug:

  • superficial and system mycoses;
  • dermatomycoses and onychomycoses;
  • mycoses of pilar part of the head;
  • vulval mycosis;
  • blastomitsetoz oral cavity, gastrointestinal tract, urinogenital bodies;
  • fungal balanitis.

Also Miconazolum can be appointed as prevention of the prevention of emergence of various fungal infections if the lowered immunological resistance is characteristic of an organism.


Tablets and solution for intravenous administration it is contraindicated to use at:

  • pregnancies;
  • inborn pathologies of functions of a liver.

Side effects

Use of Miconazolum inside can make sick, diarrhea, different types of the allergic phenomena.

At outside drawing development of local irritation and allergic reactions is not excluded.

Can be side effects as a result of intravenous administration: fever, diarrhea, dizziness, skin rash, thrombophlebitis.

The instruction on Miconazolum (A way and a dosage)

The pill Miconazolum is taken inside, at the same time intravenous administration of drug in solution can be at the same time appointed. Usually such scheme is used at treatment and prevention of mycoses of a gastrointestinal tract. For adult patients appoint on one tablet to 4-times reception. A dosage for children calculate taking into account body weight – 20mg/1 kg.

Drug in the form of gel is appointed during treatment and for the purpose of prevention of mycoses of an oral cavity of a mouth and a gastrointestinal tract. At the same time adults need to accept on a half, and little patients – on a quarter of a dosing spoon 4 times a day. Gel should not be swallowed at once, and it is better to take some time in a mouth. After elimination of symptoms about a week more is recommended to continue treatment.

Dosage forms for topical administration use for treatment of fungal infections of integuments and nails. Liquid, cream or ointment Miconazolum the application instruction recommends to inflict directly on places defeats, and then to rub them before full absorption. At daily use the medical effect is shown in 2-6 weeks. But after elimination of symptoms of an illness it is necessary to use drug not less than a week more.

During treatment of onychomycoses Miconazolum liquid nitrate is applied on the affected nails, and also adjacent skin, and then becomes covered by a bandage. Therapy proceeds is quite long – the new nail plate will not grow yet. Drug is applied at least 2 times a day.

Intravenous administration of drug is appointed at treatment of system mycoses. The average daily dosage makes 600 mg, but in need of it increase.

Introduction is carried out in one step, but slowly – for 30-60 minutes. Also perhaps drop introduction which is carried out in stages. During this procedure extra care is required. Previously ampullary solution is diluted with chloride sodium solution. It is necessary to remember that fast introduction is capable to break a cordial rhythm and to cause vomiting.

At treatment of vulval mycosis usually appoint candles Miconazolum. According to the instruction, every evening before going to bed enter on one vaginal candle as it is possible more deeply in a vagina. When symptoms of an illness disappear, it is necessary to use candles Miconazolum 2 more weeks.


Cases of overdose arise at considerable exceeding of the recommended dosing. Unpleasant effects of such situation are diarrhea and vomiting.

At the same time the symptomatic treatment is carried out, the drug dose decreases.


The tablets Miconazolum can increase activity of anticoagulants, hypoglycemic drugs which are derivatives of a sulfonilmochevina and Phenytoinum.

The combination to Carbamazepine can cause development of side effects.

Simultaneous use with Astemizol, Terfenadin and Tsizaprid quite often leads to development of arrhythmia.

Special instructions

With extra care this drug is appointed during a lactation, at a diabetes mellitus and disturbances of microcirculation.

If treatment of fungal infections of nails is carried out, then it is necessary to cut off them well. Also processing of interdigital intervals, feet is carried out, carrying the convenient and aired footwear, frequent change of socks is recommended.

For efficiency of treatment of vaginal defeats at the same time appoint therapy of the sexual partner.

At the same time it is important to consider that suppositories are capable to reduce reliability of mechanical contraception.

If during treatment local reactions develop or the long time is absent clinical improvement, then choose other treatment.

It is necessary to try that cream or gel did not get into eyes.

Terms of sale

Without recipe.

Storage conditions

Storage of any dosage form of drug requires the dark and cool place.

Period of validity

3 years.


Main analogs: Doktarin, Afloriks, Metronidazole, Dermonistat, Funginazol, Mezolitan, Mikonal, Mikostat, Neomikol, Surolan.


  • Mikonazoldarnitsa (Ukraine, Kiev)
Section: Antifungal
PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use Miconazolum surely consult with the attending physician.